Compile Data Set for Download or QSAR

Found 7 hits Enz. Inhib. hit(s) with Target = 'Formyl peptide receptor 2'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Formyl peptide receptor 2 (Mus musculus)	BDBM50559829 (CHEMBL4784510) Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccccc2)c(F)c1 Show InChI InChI=1S/C18H17F2N3O3/c1-26-11-7-13(19)15(14(20)8-11)12-9-21-17(24)16(12)23-18(25)22-10-5-3-2-4-6-10/h2-8,12,16H,9H2,1H3,(H,21,24)(H2,22,23,25)/t12-,16-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar	Purchase PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	0.5	n/a	n/a	n/a	n/a
Kyorin Pharmaceutical Co. Ltd. Curated by ChEMBL					Assay Description Agonist activity at mouse FPR2 expressed in CHO cells assessed as reduction cAMP accumulation incubated for 1 hr by TR-FRET assay				J Med Chem 63: 9003-9019 (2020)
					More data for this Ligand-Target Pair
Formyl peptide receptor 2 (Mus musculus)	BDBM50559829 (CHEMBL4784510) Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccccc2)c(F)c1 Show InChI InChI=1S/C18H17F2N3O3/c1-26-11-7-13(19)15(14(20)8-11)12-9-21-17(24)16(12)23-18(25)22-10-5-3-2-4-6-10/h2-8,12,16H,9H2,1H3,(H,21,24)(H2,22,23,25)/t12-,16-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar	Purchase PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	<1	n/a	n/a	n/a	n/a
Kyorin Pharmaceutical Co. Ltd. Curated by ChEMBL					Assay Description Agonist activity at FPR2 in mouse peritoneal macrophages assessed as inhibition of stimulated phagocytosis preincubated for 15 mins followed by FITC ...				J Med Chem 63: 9003-9019 (2020)
					More data for this Ligand-Target Pair
Formyl peptide receptor 2 (Mus musculus)	BDBM50559821 (CHEMBL4781596) Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(F)cc2)c(F)c1 Show InChI InChI=1S/C18H16F3N3O3/c1-27-11-6-13(20)15(14(21)7-11)12-8-22-17(25)16(12)24-18(26)23-10-4-2-9(19)3-5-10/h2-7,12,16H,8H2,1H3,(H,22,25)(H2,23,24,26)/t12-,16-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	1.5	n/a	n/a	n/a	n/a
Kyorin Pharmaceutical Co. Ltd. Curated by ChEMBL					Assay Description Agonist activity at mouse FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...				J Med Chem 63: 9003-9019 (2020)
					More data for this Ligand-Target Pair
Formyl peptide receptor 2 (Mus musculus)	BDBM50559840 (CHEMBL4760897) Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(Cl)s2)c(F)c1 Show InChI InChI=1S/C16H14ClF2N3O3S/c1-25-7-4-9(18)13(10(19)5-7)8-6-20-15(23)14(8)22-16(24)21-12-3-2-11(17)26-12/h2-5,8,14H,6H2,1H3,(H,20,23)(H2,21,22,24)/t8-,14-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	1.40	n/a	n/a	n/a	n/a
Kyorin Pharmaceutical Co. Ltd. Curated by ChEMBL					Assay Description Agonist activity at mouse FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...				J Med Chem 63: 9003-9019 (2020)
					More data for this Ligand-Target Pair
Formyl peptide receptor 2 (Mus musculus)	BDBM50559835 (CHEMBL4762030) Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(F)c(F)c2)c(F)c1 Show InChI InChI=1S/C18H15F4N3O3/c1-28-9-5-13(21)15(14(22)6-9)10-7-23-17(26)16(10)25-18(27)24-8-2-3-11(19)12(20)4-8/h2-6,10,16H,7H2,1H3,(H,23,26)(H2,24,25,27)/t10-,16-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	8.5	n/a	n/a	n/a	n/a
Kyorin Pharmaceutical Co. Ltd. Curated by ChEMBL					Assay Description Agonist activity at mouse FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...				J Med Chem 63: 9003-9019 (2020)
					More data for this Ligand-Target Pair
Formyl peptide receptor 2 (Mus musculus)	BDBM50559838 (CHEMBL4790836) Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccc(C)c(O)c2)c(F)c1 Show InChI InChI=1S/C19H19F2N3O4/c1-9-3-4-10(5-15(9)25)23-19(27)24-17-12(8-22-18(17)26)16-13(20)6-11(28-2)7-14(16)21/h3-7,12,17,25H,8H2,1-2H3,(H,22,26)(H2,23,24,27)/t12-,17-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	0.630	n/a	n/a	n/a	n/a
Kyorin Pharmaceutical Co. Ltd. Curated by ChEMBL					Assay Description Agonist activity at mouse FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...				J Med Chem 63: 9003-9019 (2020)
					More data for this Ligand-Target Pair
Formyl peptide receptor 2 (Mus musculus)	BDBM50559829 (CHEMBL4784510) Show SMILES COc1cc(F)c([C@@H]2CNC(=O)[C@H]2NC(=O)Nc2ccccc2)c(F)c1 Show InChI InChI=1S/C18H17F2N3O3/c1-26-11-7-13(19)15(14(20)8-11)12-9-21-17(24)16(12)23-18(25)22-10-5-3-2-4-6-10/h2-8,12,16H,9H2,1H3,(H,21,24)(H2,22,23,25)/t12-,16-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar	Purchase PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	3.40	n/a	n/a	n/a	n/a
Kyorin Pharmaceutical Co. Ltd. Curated by ChEMBL					Assay Description Agonist activity at mouse FPR2 expressed in HEK 293 cells co-expressing Galpha15 measured every 1.5 sec for 80 sec by Fluo-4 NW staining based scanni...				J Med Chem 63: 9003-9019 (2020)
					More data for this Ligand-Target Pair