Compile Data Set for Download or QSAR

Found 245 hits Enz. Inhib. hit(s) with Target = 'Glutathione reductase'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50352164 (CHEMBL1824793) Show SMILES OC(=O)CC[C@H](NC(=O)c1ccc(cc1)[N+]([O-])=O)C(O)=O Show InChI InChI=1S/C12H12N2O7/c15-10(16)6-5-9(12(18)19)13-11(17)7-1-3-8(4-2-7)14(20)21/h1-4,9H,5-6H2,(H,13,17)(H,15,16)(H,18,19)/t9-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	211	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Batman University Curated by ChEMBL					Assay Description Competitive inhibition of human erythrocyte Glutathione reductase using GSSG substrate by Lineweaver-Burk plot analysis				Bioorg Med Chem Lett 21: 5398-402 (2011) Article DOI: 10.1016/j.bmcl.2011.07.002 BindingDB Entry DOI: 10.7270/Q2V69KKH
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM94597 ((Z)-2-butenedioate;10-(1-methyl-4-piperidinylidene...) Show SMILES CN1CCC(CC1)=C1c2ccsc2C(=O)Cc2ccccc12 Show InChI InChI=1S/C19H19NOS/c1-20-9-6-13(7-10-20)18-15-5-3-2-4-14(15)12-17(21)19-16(18)8-11-22-19/h2-5,8,11H,6-7,9-10,12H2,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase DrugBank MCE PC cid PC sid UniChem Similars	Article PubMed	800	-34.8	1.20E+4	n/a	n/a	n/a	n/a	8.0	25
Ataturk University					Assay Description GR activity was determined by the method of Carlberg and Mannervik [Carlberg et al., FL:Academic Press, 72:248-254] with a Shimadzu Spectrophotometer...				J Enzyme Inhib Med Chem 27: 18-23 (2012) Article DOI: 10.3109/14756366.2011.572879 BindingDB Entry DOI: 10.7270/Q20K27GD
					More data for this Ligand-Target Pair
Glutathione reductase (Plasmodium falciparum (isolate 3D7))	BDBM50096018 (6-(3-METHYL-1,4-DIOXO-1,4-DIHYDRONAPHTHALEN-2-YL)H...) Show SMILES Cc1c(O)c2ccccc2c(O)c1C=CCCCC(O)=O Show InChI InChI=1S/C17H18O4/c1-11-12(7-3-2-4-10-15(18)19)17(21)14-9-6-5-8-13(14)16(11)20/h3,5-9,20-21H,2,4,10H2,1H3,(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université Libre de Bruxelles Curated by ChEMBL					Assay Description Inhibitory concentration against Plasmodium falciparum glutathione reductase				J Med Chem 47: 5972-83 (2004) Article DOI: 10.1021/jm0497545 BindingDB Entry DOI: 10.7270/Q20R9NW4
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50096018 (6-(3-METHYL-1,4-DIOXO-1,4-DIHYDRONAPHTHALEN-2-YL)H...) Show SMILES Cc1c(O)c2ccccc2c(O)c1C=CCCCC(O)=O Show InChI InChI=1S/C17H18O4/c1-11-12(7-3-2-4-10-15(18)19)17(21)14-9-6-5-8-13(14)16(11)20/h3,5-9,20-21H,2,4,10H2,1H3,(H,18,19)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université Libre de Bruxelles Curated by ChEMBL					Assay Description Inhibitory concentration against human glutathione reductase				J Med Chem 47: 5972-83 (2004) Article DOI: 10.1021/jm0497545 BindingDB Entry DOI: 10.7270/Q20R9NW4
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50352161 (CHEMBL1824791) Show SMILES CC(C)(C)OC(=O)N[C@@H](CCCCNC(=O)OCc1ccccc1Cl)C(=O)Oc1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C25H30ClN3O8/c1-25(2,3)37-24(32)28-21(22(30)36-19-13-11-18(12-14-19)29(33)34)10-6-7-15-27-23(31)35-16-17-8-4-5-9-20(17)26/h4-5,8-9,11-14,21H,6-7,10,15-16H2,1-3H3,(H,27,31)(H,28,32)/t21-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem	Article PubMed	4.16E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Batman University Curated by ChEMBL					Assay Description Non-Competitive inhibition of human erythrocyte Glutathione reductase using GSSG substrate by Lineweaver-Burk plot analysis				Bioorg Med Chem Lett 21: 5398-402 (2011) Article DOI: 10.1016/j.bmcl.2011.07.002 BindingDB Entry DOI: 10.7270/Q2V69KKH
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50352163 (CHEMBL1824792) Show SMILES CC[C@H](CO)NCc1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C11H16N2O3/c1-2-10(8-14)12-7-9-3-5-11(6-4-9)13(15)16/h3-6,10,12,14H,2,7-8H2,1H3/t10-/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem	Article PubMed	4.57E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Batman University Curated by ChEMBL					Assay Description Competitive inhibition of human erythrocyte Glutathione reductase using GSSG substrate by Lineweaver-Burk plot analysis				Bioorg Med Chem Lett 21: 5398-402 (2011) Article DOI: 10.1016/j.bmcl.2011.07.002 BindingDB Entry DOI: 10.7270/Q2V69KKH
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50056998 (4-Hydroxy-1,1-dioxo-1,2-dihydro-1lambda*6*-benzo[e...) Show SMILES CN1C(C(=O)Nc2ncc(C)s2)=C(O)c2ccccc2S1(=O)=O Show InChI InChI=1S/C14H13N3O4S2/c1-8-7-15-14(22-8)16-13(19)11-12(18)9-5-3-4-6-10(9)23(20,21)17(11)2/h3-7,18H,1-2H3,(H,15,16,19)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	6.10E+3	-29.8	2.90E+4	n/a	n/a	n/a	n/a	8.0	25
Ataturk University					Assay Description GR activity was determined by the method of Carlberg and Mannervik [Carlberg et al., FL:Academic Press, 72:248-254] with a Shimadzu Spectrophotometer...				J Enzyme Inhib Med Chem 27: 18-23 (2012) Article DOI: 10.3109/14756366.2011.572879 BindingDB Entry DOI: 10.7270/Q20K27GD
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50422689 (640/359 | CEFUROXIME) Show SMILES CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(COC(N)=O)=C(N2C1=O)C(O)=O)c1ccco1 Show InChI InChI=1S/C16H16N4O8S/c1-26-19-9(8-3-2-4-27-8)12(21)18-10-13(22)20-11(15(23)24)7(5-28-16(17)25)6-29-14(10)20/h2-4,10,14H,5-6H2,1H3,(H2,17,25)(H,18,21)(H,23,24)/b19-9-/t10-,14-/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	1.04E+4	n/a	1.88E+4	n/a	n/a	n/a	n/a	8.0	n/a
Ondokuz Mayis University					Assay Description Enzymatic activity was measured by Beutler's method with a Shimadzu Spectrophotometer UV-(1208), at 25°C. The assay system contained 100 mM Tris-...				J Enzyme Inhib Med Chem 28: 824-9 (2013) Article DOI: 10.3109/14756366.2012.688042 BindingDB Entry DOI: 10.7270/Q21J98P4
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50316592 ((2R(S),7R(S))-7-Hydroxybicyclo[2.2.1]heptan-2-yl n...) Show SMILES O[C@@H]1C2CCC1[C@@H](C2)O[N+]([O-])=O Show InChI InChI=1S/C7H11NO4/c9-7-4-1-2-5(7)6(3-4)12-8(10)11/h4-7,9H,1-3H2/t4?,5?,6-,7-/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.17E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Atat£rk University Curated by ChEMBL					Assay Description Inhibition of human erythrocyte glutathione reductase				Bioorg Med Chem Lett 19: 3661-3 (2009) Article DOI: 10.1016/j.bmcl.2009.04.087 BindingDB Entry DOI: 10.7270/Q2930V34
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM24778 (2-methyl-1,4-dihydronaphthalene-1,4-dione | 2-meth...) Show SMILES CC1=CC(=O)c2ccccc2C1=O Show InChI InChI=1S/C11H8O2/c1-7-6-10(12)8-4-2-3-5-9(8)11(7)13/h2-6H,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.21E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université Libre de Bruxelles Curated by ChEMBL					Assay Description Inhibitory concentration against human glutathione reductase (In presence of glutathione disulfide)				J Med Chem 47: 5972-83 (2004) Article DOI: 10.1021/jm0497545 BindingDB Entry DOI: 10.7270/Q20R9NW4
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50293668 ((2S(R),7R(S))-7-Hydroxybicyclo[2.2.1]heptan-2-yl n...) Show SMILES OC1C2CCC1C(C2)O[N+]([O-])=O Show InChI InChI=1S/C7H11NO4/c9-7-4-1-2-5(7)6(3-4)12-8(10)11/h4-7,9H,1-3H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.31E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Atat£rk University Curated by ChEMBL					Assay Description Inhibition of human erythrocyte glutathione reductase				Bioorg Med Chem Lett 19: 3661-3 (2009) Article DOI: 10.1016/j.bmcl.2009.04.087 BindingDB Entry DOI: 10.7270/Q2930V34
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM24778 (2-methyl-1,4-dihydronaphthalene-1,4-dione | 2-meth...) Show SMILES CC1=CC(=O)c2ccccc2C1=O Show InChI InChI=1S/C11H8O2/c1-7-6-10(12)8-4-2-3-5-9(8)11(7)13/h2-6H,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.61E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université Libre de Bruxelles Curated by ChEMBL					Assay Description Inhibitory concentration against human glutathione reductase (In presence of NADPH)				J Med Chem 47: 5972-83 (2004) Article DOI: 10.1021/jm0497545 BindingDB Entry DOI: 10.7270/Q20R9NW4
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50049707 ((6R,7R)-7-{2-(2-Amino-thiazol-4-yl)-2-[(Z)-methoxy...) Show SMILES CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(CSc3nc(=O)c(=O)[nH]n3C)=C(N2C1=O)C(O)=O)c1csc(N)n1 Show InChI InChI=1S/C18H18N8O7S3/c1-25-18(22-12(28)13(29)23-25)36-4-6-3-34-15-9(14(30)26(15)10(6)16(31)32)21-11(27)8(24-33-2)7-5-35-17(19)20-7/h5,9,15H,3-4H2,1-2H3,(H2,19,20)(H,21,27)(H,23,29)(H,31,32)/b24-8-/t9-,15-/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	1.73E+4	n/a	2.13E+4	n/a	n/a	n/a	n/a	8.0	n/a
Ondokuz Mayis University					Assay Description Enzymatic activity was measured by Beutler's method with a Shimadzu Spectrophotometer UV-(1208), at 25°C. The assay system contained 100 mM Tris-...				J Enzyme Inhib Med Chem 28: 824-9 (2013) Article DOI: 10.3109/14756366.2012.688042 BindingDB Entry DOI: 10.7270/Q21J98P4
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50336640 ((nifedipine) 2,6-Dimethyl-4-(2-nitro-phenyl)-1,4-d...) Show SMILES COC(=O)C1C(C(C(=O)OC)=C(C)N=C1C)c1ccccc1[N+]([O-])=O Show InChI InChI=1S/C17H18N2O6/c1-9-13(16(20)24-3)15(14(10(2)18-9)17(21)25-4)11-7-5-6-8-12(11)19(22)23/h5-8,13,15H,1-4H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	CHEBI PC cid PC sid UniChem Patents Similars	Article PubMed	1.74E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Batman University Curated by ChEMBL					Assay Description Competitive inhibition of human erythrocyte Glutathione reductase using GSSG substrate by Lineweaver-Burk plot analysis				Bioorg Med Chem Lett 21: 5398-402 (2011) Article DOI: 10.1016/j.bmcl.2011.07.002 BindingDB Entry DOI: 10.7270/Q2V69KKH
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50293667 ((1R(S),2R(S),3S(R),4S(R))-2,3-Dihydroxycyclo-hexan...) Show SMILES OC1C(O)C(CCC1O[N+]([O-])=O)O[N+]([O-])=O Show InChI InChI=1S/C6H10N2O8/c9-5-3(15-7(11)12)1-2-4(6(5)10)16-8(13)14/h3-6,9-10H,1-2H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.74E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Atat£rk University Curated by ChEMBL					Assay Description Inhibition of human erythrocyte glutathione reductase				Bioorg Med Chem Lett 19: 3661-3 (2009) Article DOI: 10.1016/j.bmcl.2009.04.087 BindingDB Entry DOI: 10.7270/Q2930V34
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50293666 ((1S(R),3S(R),4S(R),6S(R))-4,6-Dihydroxycyclo-hexan...) Show SMILES OC1CC(O)C(CC1O[N+]([O-])=O)O[N+]([O-])=O Show InChI InChI=1S/C6H10N2O8/c9-3-1-4(10)6(16-8(13)14)2-5(3)15-7(11)12/h3-6,9-10H,1-2H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.79E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Atat£rk University Curated by ChEMBL					Assay Description Inhibition of human erythrocyte glutathione reductase				Bioorg Med Chem Lett 19: 3661-3 (2009) Article DOI: 10.1016/j.bmcl.2009.04.087 BindingDB Entry DOI: 10.7270/Q2930V34
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50293665 ((1R(S),2R(S),4R(S),5R(S))-2,5-Dihydroxycyclo-hexan...) Show SMILES OC1CC(O[N+]([O-])=O)C(O)CC1O[N+]([O-])=O Show InChI InChI=1S/C6H10N2O8/c9-3-1-5(15-7(11)12)4(10)2-6(3)16-8(13)14/h3-6,9-10H,1-2H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.84E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Atat£rk University Curated by ChEMBL					Assay Description Inhibition of human erythrocyte glutathione reductase				Bioorg Med Chem Lett 19: 3661-3 (2009) Article DOI: 10.1016/j.bmcl.2009.04.087 BindingDB Entry DOI: 10.7270/Q2930V34
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50293664 (9(R(S))-Hydroxy-1,2,3,4-tetrahydro-1,4-methano-nap...) Show SMILES OC1C2CC(O[N+]([O-])=O)C1c1ccccc21 Show InChI InChI=1S/C11H11NO4/c13-11-8-5-9(16-12(14)15)10(11)7-4-2-1-3-6(7)8/h1-4,8-11,13H,5H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.88E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Atat£rk University Curated by ChEMBL					Assay Description Inhibition of human erythrocyte glutathione reductase				Bioorg Med Chem Lett 19: 3661-3 (2009) Article DOI: 10.1016/j.bmcl.2009.04.087 BindingDB Entry DOI: 10.7270/Q2930V34
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50293663 ((1S(R),2S(R),5R(S),6R(S))-5-Bromo-9-oxabicyclo[4.2...) Show SMILES [O-][N+](=O)OC1CCC(Br)C2CCC1O2 Show InChI InChI=1S/C8H12BrNO4/c9-5-1-2-8(14-10(11)12)7-4-3-6(5)13-7/h5-8H,1-4H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.15E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Atat£rk University Curated by ChEMBL					Assay Description Inhibition of human erythrocyte glutathione reductase				Bioorg Med Chem Lett 19: 3661-3 (2009) Article DOI: 10.1016/j.bmcl.2009.04.087 BindingDB Entry DOI: 10.7270/Q2930V34
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50293661 (CHEMBL556256 | trans-(1S(R),2S(R))-2-Hydroxycycloo...) Show SMILES O[C@H]1CCCCCC[C@@H]1O[N+]([O-])=O Show InChI InChI=1S/C8H15NO4/c10-7-5-3-1-2-4-6-8(7)13-9(11)12/h7-8,10H,1-6H2/t7-,8-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.19E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Atat£rk University Curated by ChEMBL					Assay Description Inhibition of human erythrocyte glutathione reductase				Bioorg Med Chem Lett 19: 3661-3 (2009) Article DOI: 10.1016/j.bmcl.2009.04.087 BindingDB Entry DOI: 10.7270/Q2930V34
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM237182 (Ceftizoxime) Show SMILES CO\N=C(/C(=O)N[C@H]1[C@H]2SCC=C(N2C1=O)C(O)=O)c1csc(N)n1 Show InChI InChI=1S/C13H13N5O5S2/c1-23-17-7(5-4-25-13(14)15-5)9(19)16-8-10(20)18-6(12(21)22)2-3-24-11(8)18/h2,4,8,11H,3H2,1H3,(H2,14,15)(H,16,19)(H,21,22)/b17-7-/t8-,11-/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase DrugBank KEGG PC cid PC sid UniChem	Article PubMed	2.28E+4	n/a	3.97E+4	n/a	n/a	n/a	n/a	8.0	n/a
Ondokuz Mayis University					Assay Description Enzymatic activity was measured by Beutler's method with a Shimadzu Spectrophotometer UV-(1208), at 25°C. The assay system contained 100 mM Tris-...				J Enzyme Inhib Med Chem 28: 824-9 (2013) Article DOI: 10.3109/14756366.2012.688042 BindingDB Entry DOI: 10.7270/Q21J98P4
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50293660 (CHEMBL563619 | trans-(R(S))-2-Hydroxy-1-phenylethy...) Show SMILES OC[C@H](O[N+]([O-])=O)c1ccccc1 Show InChI InChI=1S/C8H9NO4/c10-6-8(13-9(11)12)7-4-2-1-3-5-7/h1-5,8,10H,6H2/t8-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem	Article PubMed	2.56E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Atat£rk University Curated by ChEMBL					Assay Description Inhibition of human erythrocyte glutathione reductase				Bioorg Med Chem Lett 19: 3661-3 (2009) Article DOI: 10.1016/j.bmcl.2009.04.087 BindingDB Entry DOI: 10.7270/Q2930V34
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50390999 (CEFOPERAZONE) Show SMILES CCN1CCN(C(=O)N[C@@H](C(=O)N[C@H]2[C@H]3SCC(CSc4nnnn4C)=C(N3C2=O)C(O)=O)c2ccc(O)cc2)C(=O)C1=O Show InChI InChI=1S/C25H27N9O8S2/c1-3-32-8-9-33(21(39)20(32)38)24(42)27-15(12-4-6-14(35)7-5-12)18(36)26-16-19(37)34-17(23(40)41)13(10-43-22(16)34)11-44-25-28-29-30-31(25)2/h4-7,15-16,22,35H,3,8-11H2,1-2H3,(H,26,36)(H,27,42)(H,40,41)/t15-,16-,22-/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	2.87E+4	n/a	4.84E+4	n/a	n/a	n/a	n/a	8.0	n/a
Ondokuz Mayis University					Assay Description Enzymatic activity was measured by Beutler's method with a Shimadzu Spectrophotometer UV-(1208), at 25°C. The assay system contained 100 mM Tris-...				J Enzyme Inhib Med Chem 28: 824-9 (2013) Article DOI: 10.3109/14756366.2012.688042 BindingDB Entry DOI: 10.7270/Q21J98P4
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50293658 (CHEMBL555721 | trans-(1S(R),6S(R))-6-Hydroxycycloh...) Show SMILES O[C@H]1CC=CC[C@@H]1O[N+]([O-])=O Show InChI InChI=1S/C6H9NO4/c8-5-3-1-2-4-6(5)11-7(9)10/h1-2,5-6,8H,3-4H2/t5-,6-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem	Article PubMed	3.51E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Atat£rk University Curated by ChEMBL					Assay Description Inhibition of human erythrocyte glutathione reductase				Bioorg Med Chem Lett 19: 3661-3 (2009) Article DOI: 10.1016/j.bmcl.2009.04.087 BindingDB Entry DOI: 10.7270/Q2930V34
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM17657 ((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...) Show SMILES N[C@@H](CCC(O)=O)C(O)=O Show InChI InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	4.27E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Batman University Curated by ChEMBL					Assay Description Competitive inhibition of human erythrocyte Glutathione reductase using GSSG substrate by Lineweaver-Burk plot analysis				Bioorg Med Chem Lett 21: 5398-402 (2011) Article DOI: 10.1016/j.bmcl.2011.07.002 BindingDB Entry DOI: 10.7270/Q2V69KKH
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50293659 (CHEMBL562358 | trans-(1S(R),2S(R))-2-Hydroxycycloh...) Show SMILES O[C@H]1CCCC[C@@H]1O[N+]([O-])=O Show InChI InChI=1S/C6H11NO4/c8-5-3-1-2-4-6(5)11-7(9)10/h5-6,8H,1-4H2/t5-,6-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.37E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Atat£rk University Curated by ChEMBL					Assay Description Inhibition of human erythrocyte glutathione reductase				Bioorg Med Chem Lett 19: 3661-3 (2009) Article DOI: 10.1016/j.bmcl.2009.04.087 BindingDB Entry DOI: 10.7270/Q2930V34
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50293662 (CHEMBL559615 | trans-(1S(R),8S(R),Z)-8-Hydroxycycl...) Show SMILES O[C@H]1CC\C=C/CC[C@@H]1O[N+]([O-])=O Show InChI InChI=1S/C8H13NO4/c10-7-5-3-1-2-4-6-8(7)13-9(11)12/h1-2,7-8,10H,3-6H2/b2-1-/t7-,8-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem	Article PubMed	4.43E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Atat£rk University Curated by ChEMBL					Assay Description Inhibition of human erythrocyte glutathione reductase				Bioorg Med Chem Lett 19: 3661-3 (2009) Article DOI: 10.1016/j.bmcl.2009.04.087 BindingDB Entry DOI: 10.7270/Q2930V34
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50352165 (LYSINE) Show SMILES N[C@@H](CCCC[NH3+])C(O)=O Show InChI InChI=1S/C6H14N2O2/c7-4-2-1-3-5(8)6(9)10/h5H,1-4,7-8H2,(H,9,10)/p+1/t5-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	5.46E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Batman University Curated by ChEMBL					Assay Description Competitive inhibition of human erythrocyte Glutathione reductase using GSSG substrate by Lineweaver-Burk plot analysis				Bioorg Med Chem Lett 21: 5398-402 (2011) Article DOI: 10.1016/j.bmcl.2011.07.002 BindingDB Entry DOI: 10.7270/Q2V69KKH
					More data for this Ligand-Target Pair
Glutathione reductase (Saccharomyces cerevisiae)	BDBM50171438 (2-Acetylamino-3-[4-(2-acetylamino-2-carboxy-ethyls...) Show SMILES CC(=O)NC(CSC(=O)Nc1ccc(NC(=O)SCC(NC(C)=O)C(O)=O)cc1)C(O)=O Show InChI InChI=1S/C18H22N4O8S2/c1-9(23)19-13(15(25)26)7-31-17(29)21-11-3-5-12(6-4-11)22-18(30)32-8-14(16(27)28)20-10(2)24/h3-6,13-14H,7-8H2,1-2H3,(H,19,23)(H,20,24)(H,21,29)(H,22,30)(H,25,26)(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	8.80E+4	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
South Dakota State University Curated by ChEMBL					Assay Description Inhibition of yeast glutathione reductase for 30 minutes pH 7.4 at 25 degree C at 0.2 mM				J Med Chem 48: 5224-31 (2005) Article DOI: 10.1021/jm050030i BindingDB Entry DOI: 10.7270/Q2SQ8ZW8
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50170723 (1,1'-Hexamethylene bis(5-(p-chlorophenyl)biguanide...) Show SMILES NC(NC(N)=Nc1ccc(Cl)cc1)=NCCCCCCN=C(N)N=C(N)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C22H30Cl2N10/c23-15-5-9-17(10-6-15)31-21(27)33-19(25)29-13-3-1-2-4-14-30-20(26)34-22(28)32-18-11-7-16(24)8-12-18/h5-12H,1-4,13-14H2,(H5,25,27,29,31,33)(H5,26,28,30,32,34)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	CHEBI CHEMBL PC cid PC sid UniChem Patents	Article PubMed	1.92E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t Heidelberg Curated by ChEMBL					Assay Description Inhibitory constant against human glutathione reductase				J Med Chem 48: 4793-802 (2005) Article DOI: 10.1021/jm050027z BindingDB Entry DOI: 10.7270/Q2XK8GB5
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50352162 (NITROBENZENE) Show SMILES [O-][N+](=O)c1ccccc1 Show InChI InChI=1S/C6H5NO2/c8-7(9)6-4-2-1-3-5-6/h1-5H	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEBI KEGG MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	2.74E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Batman University Curated by ChEMBL					Assay Description Competitive inhibition of human erythrocyte Glutathione reductase using GSSG substrate by Lineweaver-Burk plot analysis				Bioorg Med Chem Lett 21: 5398-402 (2011) Article DOI: 10.1016/j.bmcl.2011.07.002 BindingDB Entry DOI: 10.7270/Q2V69KKH
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM235694 (Phenyramidol-HCl) Show SMILES OC(CNc1ccccn1)c1ccccc1 Show InChI InChI=1S/C13H14N2O/c16-12(11-6-2-1-3-7-11)10-15-13-8-4-5-9-14-13/h1-9,12,16H,10H2,(H,14,15)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase PC cid PC sid UniChem	Article PubMed	4.34E+5	-19.2	9.90E+5	n/a	n/a	n/a	n/a	8.0	25
Ataturk University					Assay Description GR activity was determined by the method of Carlberg and Mannervik [Carlberg et al., FL:Academic Press, 72:248-254] with a Shimadzu Spectrophotometer...				J Enzyme Inhib Med Chem 27: 18-23 (2012) Article DOI: 10.3109/14756366.2011.572879 BindingDB Entry DOI: 10.7270/Q20K27GD
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50091152 (CHEMBL106108 | [3-(2-Chloro-phenothiazin-10-yl)-pr...) Show SMILES C[N+](C)(CCCN1c2ccccc2Sc2ccc(Cl)cc12)CC1CCCCC1 Show InChI InChI=1S/C24H32ClN2S/c1-27(2,18-19-9-4-3-5-10-19)16-8-15-26-21-11-6-7-12-23(21)28-24-14-13-20(25)17-22(24)26/h6-7,11-14,17,19H,3-5,8-10,15-16,18H2,1-2H3/q+1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Inhibitory activity against Human Erythrocyte glutathione reductase (GR).				J Med Chem 43: 3148-56 (2000) Article DOI: 10.1021/jm000156+ BindingDB Entry DOI: 10.7270/Q2R78FXC
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50091149 ((4-Chloro-benzyl)-[3-(2-chloro-phenothiazin-10-yl)...) Show SMILES C[N+](C)(CCCN1c2ccccc2Sc2ccc(Cl)cc12)Cc1ccc(Cl)cc1 Show InChI InChI=1S/C24H25Cl2N2S/c1-28(2,17-18-8-10-19(25)11-9-18)15-5-14-27-21-6-3-4-7-23(21)29-24-13-12-20(26)16-22(24)27/h3-4,6-13,16H,5,14-15,17H2,1-2H3/q+1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Inhibitory activity against Human Erythrocyte glutathione reductase (GR).				J Med Chem 43: 3148-56 (2000) Article DOI: 10.1021/jm000156+ BindingDB Entry DOI: 10.7270/Q2R78FXC
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50093207 ((E)-3-(3,4-Dihydroxy-phenyl)-N-[3-(4-{3-[(E)-3-(3,...) Show SMILES Oc1ccc(\C=C\C(=O)NCCCNCCCCNCCCNC(=O)\C=C\c2ccc(O)c(O)c2)cc1O Show InChI InChI=1S/C28H38N4O6/c33-23-9-5-21(19-25(23)35)7-11-27(37)31-17-3-15-29-13-1-2-14-30-16-4-18-32-28(38)12-8-22-6-10-24(34)26(36)20-22/h5-12,19-20,29-30,33-36H,1-4,13-18H2,(H,31,37)(H,32,38)/b11-7+,12-8+	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Southamton Curated by ChEMBL					Assay Description The compound was evaluated for inhibition of human Glutathione reductase				Bioorg Med Chem Lett 10: 2367-9 (2001) Article DOI: 10.1016/s0960-894x(00)00471-6 BindingDB Entry DOI: 10.7270/Q2HH6KKC
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM233150 (Gadopentetic acid) Show SMILES OC(=O)CN(CCN(CCN(CC(O)=O)CC([O-])=O)CC([O-])=O)CC([O-])=O Show InChI InChI=1S/C14H23N3O10/c18-10(19)5-15(1-3-16(6-11(20)21)7-12(22)23)2-4-17(8-13(24)25)9-14(26)27/h1-9H2,(H,18,19)(H,20,21)(H,22,23)(H,24,25)(H,26,27)/p-3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase DrugBank PC cid PC sid UniChem	Article PubMed	2.88E+7	-8.79	1.38E+8	n/a	n/a	n/a	n/a	8.0	25
Ataturk University					Assay Description GR activity was determined by the method of Carlberg and Mannervik [Carlberg et al., FL:Academic Press, 72:248-254] with a Shimadzu Spectrophotometer...				J Enzyme Inhib Med Chem 27: 18-23 (2012) Article DOI: 10.3109/14756366.2011.572879 BindingDB Entry DOI: 10.7270/Q20K27GD
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50176071 (2-(2-Amino-ethylamino)-N-(7-{2-[N'-(5-nitro-furan-...) Show SMILES [O-][N+](=O)c1ccc(o1)C(=O)NNC(=O)Cc1ccc2ccc(NC(=O)C[NH+]3CC[NH2+][Pt]3(Cl)Cl)cc2c1 Show InChI InChI=1S/C21H22N6O6.2ClH.Pt/c22-7-8-23-12-19(29)24-16-4-3-14-2-1-13(9-15(14)11-16)10-18(28)25-26-21(30)17-5-6-20(33-17)27(31)32;;;/h1-6,9,11,23H,7-8,10,12,22H2,(H,24,29)(H,25,28)(H,26,30);2*1H;/q;;;+4/p-2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
UMR 8525 CNRS-Université Lille II-Institut Pasteur de Lille Curated by ChEMBL					Assay Description Inhibitory concentration against human glutathione reductase				J Med Chem 48: 7024-39 (2005) Article DOI: 10.1021/jm050256l BindingDB Entry DOI: 10.7270/Q2CN73F9
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50121447 (5-Nitro-furan-2-carboxylic acid N'-(2-naphthalen-2...) Show SMILES [O-][N+](=O)c1ccc(o1)C(=O)NNC(=O)Cc1ccc2ccccc2c1 Show InChI InChI=1S/C17H13N3O5/c21-15(10-11-5-6-12-3-1-2-4-13(12)9-11)18-19-17(22)14-7-8-16(25-14)20(23)24/h1-9H,10H2,(H,18,21)(H,19,22)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
UMR 8525 CNRS-Université Lille II-Institut Pasteur de Lille Curated by ChEMBL					Assay Description Inhibitory concentration against human glutathione reductase				J Med Chem 48: 7024-39 (2005) Article DOI: 10.1021/jm050256l BindingDB Entry DOI: 10.7270/Q2CN73F9
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50352164 (CHEMBL1824793) Show SMILES OC(=O)CC[C@H](NC(=O)c1ccc(cc1)[N+]([O-])=O)C(O)=O Show InChI InChI=1S/C12H12N2O7/c15-10(16)6-5-9(12(18)19)13-11(17)7-1-3-8(4-2-7)14(20)21/h1-4,9H,5-6H2,(H,13,17)(H,15,16)(H,18,19)/t9-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	344	n/a	n/a	n/a	n/a	n/a	n/a
Batman University Curated by ChEMBL					Assay Description Inhibition of human erythrocyte Glutathione reductase				Bioorg Med Chem Lett 21: 5398-402 (2011) Article DOI: 10.1016/j.bmcl.2011.07.002 BindingDB Entry DOI: 10.7270/Q2V69KKH
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50096018 (6-(3-METHYL-1,4-DIOXO-1,4-DIHYDRONAPHTHALEN-2-YL)H...) Show SMILES Cc1c(O)c2ccccc2c(O)c1C=CCCCC(O)=O Show InChI InChI=1S/C17H18O4/c1-11-12(7-3-2-4-10-15(18)19)17(21)14-9-6-5-8-13(14)16(11)20/h3,5-9,20-21H,2,4,10H2,1H3,(H,18,19)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
UMR 8525 CNRS-Université Lille II-Institut Pasteur de Lille Curated by ChEMBL					Assay Description In vitro inhibition of Plasmodium falciparum Glutathione Reductase				J Med Chem 44: 4268-76 (2001) Article DOI: 10.1021/jm010268g BindingDB Entry DOI: 10.7270/Q20V8C2Q
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50096035 (6-(8-Hydroxy-3-methyl-1,4-dioxo-1,4-dihydro-naphth...) Show SMILES Cc1c(O)c2cccc(O)c2c(O)c1C=CCCCC(O)=O Show InChI InChI=1S/C17H18O5/c1-10-11(6-3-2-4-9-14(19)20)17(22)15-12(16(10)21)7-5-8-13(15)18/h3,5-8,18,21-22H,2,4,9H2,1H3,(H,19,20)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
UMR 8525 CNRS-Université Lille II-Institut Pasteur de Lille Curated by ChEMBL					Assay Description In vitro inhibition of human Glutathione Reductase				J Med Chem 44: 4268-76 (2001) Article DOI: 10.1021/jm010268g BindingDB Entry DOI: 10.7270/Q20V8C2Q
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50051997 (10-(4-Chloro-phenyl)-8-fluoro-3-methyl-10H-benzo[g...) Show SMILES Cn1c(=O)nc2n(-c3ccc(Cl)cc3)c3cc(F)ccc3nc2c1=O Show InChI InChI=1S/C17H10ClFN4O2/c1-22-16(24)14-15(21-17(22)25)23(11-5-2-9(18)3-6-11)13-8-10(19)4-7-12(13)20-14/h2-8H,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institut für Biochemie II der Universität Curated by ChEMBL					Assay Description Inhibitory activity against human glutathione reductase in presence of 100 microM GSSG				J Med Chem 39: 1549-54 (1996) Article DOI: 10.1021/jm950511+ BindingDB Entry DOI: 10.7270/Q2F18XTZ
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50096062 (5-(8-Hydroxy-3-methyl-1,4-dioxo-1,4-dihydro-naphth...) Show SMILES Cc1c(O)c2cccc(O)c2c(O)c1C=CCCC(O)=O Show InChI InChI=1S/C16H16O5/c1-9-10(5-2-3-8-13(18)19)16(21)14-11(15(9)20)6-4-7-12(14)17/h2,4-7,17,20-21H,3,8H2,1H3,(H,18,19)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
UMR 8525 CNRS-Université Lille II-Institut Pasteur de Lille Curated by ChEMBL					Assay Description In vitro inhibition of human Glutathione Reductase				J Med Chem 44: 4268-76 (2001) Article DOI: 10.1021/jm010268g BindingDB Entry DOI: 10.7270/Q20V8C2Q
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50052014 (3-Methyl-10-(3-trifluoromethyl-phenyl)-10H-benzo[g...) Show SMILES Cn1c(=O)nc2n(-c3cccc(c3)C(F)(F)F)c3ccccc3nc2c1=O Show InChI InChI=1S/C18H11F3N4O2/c1-24-16(26)14-15(23-17(24)27)25(13-8-3-2-7-12(13)22-14)11-6-4-5-10(9-11)18(19,20)21/h2-9H,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institut für Biochemie II der Universität Curated by ChEMBL					Assay Description Inhibitory activity against human glutathione reductase in presence of 100 microM GSSG				J Med Chem 39: 1549-54 (1996) Article DOI: 10.1021/jm950511+ BindingDB Entry DOI: 10.7270/Q2F18XTZ
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50052000 (10-(3-Trifluoromethyl-phenyl)-10H-benzo[g]pteridin...) Show SMILES FC(F)(F)c1cccc(c1)-n1c2ccccc2nc2c1nc(=O)[nH]c2=O Show InChI InChI=1S/C17H9F3N4O2/c18-17(19,20)9-4-3-5-10(8-9)24-12-7-2-1-6-11(12)21-13-14(24)22-16(26)23-15(13)25/h1-8H,(H,23,25,26)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institut für Biochemie II der Universität Curated by ChEMBL					Assay Description Inhibitory activity against human glutathione reductase in presence of 100 microM GSSG				J Med Chem 39: 1549-54 (1996) Article DOI: 10.1021/jm950511+ BindingDB Entry DOI: 10.7270/Q2F18XTZ
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50096035 (6-(8-Hydroxy-3-methyl-1,4-dioxo-1,4-dihydro-naphth...) Show SMILES Cc1c(O)c2cccc(O)c2c(O)c1C=CCCCC(O)=O Show InChI InChI=1S/C17H18O5/c1-10-11(6-3-2-4-9-14(19)20)17(22)15-12(16(10)21)7-5-8-13(15)18/h3,5-8,18,21-22H,2,4,9H2,1H3,(H,19,20)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
UMR 8525 CNRS-Université Lille II-Institut Pasteur de Lille Curated by ChEMBL					Assay Description In vitro inhibition of Plasmodium falciparum Glutathione Reductase				J Med Chem 44: 4268-76 (2001) Article DOI: 10.1021/jm010268g BindingDB Entry DOI: 10.7270/Q20V8C2Q
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50096018 (6-(3-METHYL-1,4-DIOXO-1,4-DIHYDRONAPHTHALEN-2-YL)H...) Show SMILES Cc1c(O)c2ccccc2c(O)c1C=CCCCC(O)=O Show InChI InChI=1S/C17H18O4/c1-11-12(7-3-2-4-10-15(18)19)17(21)14-9-6-5-8-13(14)16(11)20/h3,5-9,20-21H,2,4,10H2,1H3,(H,18,19)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Libre de Bruxelles Curated by ChEMBL					Assay Description Inhibitory concentration against human glutathione reductase in the the presence of 200 uM exogenous NADP				J Med Chem 47: 5972-83 (2004) Article DOI: 10.1021/jm0497545 BindingDB Entry DOI: 10.7270/Q20R9NW4
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50096018 (6-(3-METHYL-1,4-DIOXO-1,4-DIHYDRONAPHTHALEN-2-YL)H...) Show SMILES Cc1c(O)c2ccccc2c(O)c1C=CCCCC(O)=O Show InChI InChI=1S/C17H18O4/c1-11-12(7-3-2-4-10-15(18)19)17(21)14-9-6-5-8-13(14)16(11)20/h3,5-9,20-21H,2,4,10H2,1H3,(H,18,19)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Libre de Bruxelles Curated by ChEMBL					Assay Description Inhibitory concentration against human glutathione reductase in the absence of glucose-6-phosphate dehydrogenase (G6PDH)				J Med Chem 47: 5972-83 (2004) Article DOI: 10.1021/jm0497545 BindingDB Entry DOI: 10.7270/Q20R9NW4
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50051998 (3-Methyl-10-naphthalen-1-yl-10H-benzo[g]pteridine-...) Show SMILES Cn1c(=O)nc2n(-c3cccc4ccccc34)c3ccccc3nc2c1=O Show InChI InChI=1S/C21H14N4O2/c1-24-20(26)18-19(23-21(24)27)25(17-11-5-4-10-15(17)22-18)16-12-6-8-13-7-2-3-9-14(13)16/h2-12H,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institut für Biochemie II der Universität Curated by ChEMBL					Assay Description Inhibitory activity against human glutathione reductase in presence of 100 microM GSSG				J Med Chem 39: 1549-54 (1996) Article DOI: 10.1021/jm950511+ BindingDB Entry DOI: 10.7270/Q2F18XTZ
					More data for this Ligand-Target Pair
Glutathione reductase, mitochondrial (Homo sapiens (Human))	BDBM50052004 (3-Methyl-10-phenyl-10H-benzo[g]pteridine-2,4-dione...) Show SMILES Cn1c(=O)nc2n(-c3ccccc3)c3ccccc3nc2c1=O Show InChI InChI=1S/C17H12N4O2/c1-20-16(22)14-15(19-17(20)23)21(11-7-3-2-4-8-11)13-10-6-5-9-12(13)18-14/h2-10H,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institut für Biochemie II der Universität Curated by ChEMBL					Assay Description Inhibitory activity against human glutathione reductase in presence of 100 microM GSSG				J Med Chem 39: 1549-54 (1996) Article DOI: 10.1021/jm950511+ BindingDB Entry DOI: 10.7270/Q2F18XTZ
					More data for this Ligand-Target Pair

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