Compile Data Set for Download or QSAR

Found 44 hits Enz. Inhib. hit(s) with Target = 'Lactoperoxidase'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lactoperoxidase (LPO) (Bos taurus (Bovine))	BDBM217355 (4-benzyl-2-hydroxybenzenecarbohydroxamic acid (HX2...) Show SMILES ONC(=O)c1ccc(Cc2ccccc2)cc1O Show InChI InChI=1S/C14H13NO3/c16-13-9-11(6-7-12(13)14(17)15-18)8-10-4-2-1-3-5-10/h1-7,9,16,18H,8H2,(H,15,17)	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
University of Otago Christchurch					Assay Description The halogenation activities of LPO (EC 1.11.1.7) and TPO (EC 1.11.1.8) were determined using a modified method of that described previously [Ferrari ...				J Biol Chem 288: 36636-47 (2013) Article DOI: 10.1074/jbc.M113.507756 BindingDB Entry DOI: 10.7270/Q20K27DH
					More data for this Ligand-Target Pair
Lactoperoxidase (LPO) (Bos taurus (Bovine))	BDBM50015089 (2,N-Dihydroxy-benzamide | CHEMBL309339 | N,2-dihyd...) Show SMILES ONC(=O)c1ccccc1O Show InChI InChI=1S/C7H7NO3/c9-6-4-2-1-3-5(6)7(10)8-11/h1-4,9,11H,(H,8,10)	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
University of Otago Christchurch					Assay Description The halogenation activities of LPO (EC 1.11.1.7) and TPO (EC 1.11.1.8) were determined using a modified method of that described previously [Ferrari ...				J Biol Chem 288: 36636-47 (2013) Article DOI: 10.1074/jbc.M113.507756 BindingDB Entry DOI: 10.7270/Q20K27DH
					More data for this Ligand-Target Pair				3D Structure (crystal)
Lactoperoxidase (LPO) (Bos taurus (Bovine))	BDBM50238831 (CHEMBL251689) Show SMILES COc1cc(N[C@H](C)CCCN)c2ncccc2c1 Show InChI InChI=1S/C15H21N3O/c1-11(5-3-7-16)18-14-10-13(19-2)9-12-6-4-8-17-15(12)14/h4,6,8-11,18H,3,5,7,16H2,1-2H3/t11-/m1/s1	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Libre de Bruxelles Curated by ChEMBL					Assay Description Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 mins				J Med Chem 60: 6563-6586 (2017) Article DOI: 10.1021/acs.jmedchem.7b00285 BindingDB Entry DOI: 10.7270/Q27D2XD7
					More data for this Ligand-Target Pair
Lactoperoxidase (LPO) (Bos taurus (Bovine))	BDBM81461 (CAS_86-54-4 | Hydralazine | Hydralazine (HZN) | NS...) Show SMILES NNc1nncc2ccccc12 Show InChI InChI=1S/C8H8N4/c9-11-8-7-4-2-1-3-6(7)5-10-12-8/h1-5H,9H2,(H,11,12)	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	Purchase CHEBI DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Libre de Bruxelles Curated by ChEMBL					Assay Description Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 mins				J Med Chem 60: 6563-6586 (2017) Article DOI: 10.1021/acs.jmedchem.7b00285 BindingDB Entry DOI: 10.7270/Q27D2XD7
					More data for this Ligand-Target Pair
Lactoperoxidase (LPO) (Bos taurus (Bovine))	BDBM217356 (2-(benzylamino)-6-oxo-3H-pyrimidine-5-carbohydroxa...) Show SMILES ONC(=O)c1c[nH]c(NCc2ccccc2)nc1=O Show InChI InChI=1S/C12H12N4O3/c17-10-9(11(18)16-19)7-14-12(15-10)13-6-8-4-2-1-3-5-8/h1-5,7,19H,6H2,(H,16,18)(H2,13,14,15,17)	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Otago Christchurch					Assay Description The halogenation activities of LPO (EC 1.11.1.7) and TPO (EC 1.11.1.8) were determined using a modified method of that described previously [Ferrari ...				J Biol Chem 288: 36636-47 (2013) Article DOI: 10.1074/jbc.M113.507756 BindingDB Entry DOI: 10.7270/Q20K27DH
					More data for this Ligand-Target Pair
Lactoperoxidase (LPO) (Bos taurus (Bovine))	BDBM50238837 (CHEMBL581893 | GNF-Pf-3346) Show SMILES COc1ccc2c(C)nc(NC(N)=N)nc2c1 Show InChI InChI=1S/C11H13N5O/c1-6-8-4-3-7(17-2)5-9(8)15-11(14-6)16-10(12)13/h3-5H,1-2H3,(H4,12,13,14,15,16)	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Libre de Bruxelles Curated by ChEMBL					Assay Description Inhibition of cathepsin D.				J Med Chem 60: 6563-6586 (2017) Article DOI: 10.1021/acs.jmedchem.7b00285 BindingDB Entry DOI: 10.7270/Q27D2XD7
					More data for this Ligand-Target Pair
Lactoperoxidase (LPO) (Bos taurus (Bovine))	BDBM50238832 (CHEMBL4080413) Show SMILES Cc1nc(N=C(N)N)nc2cc(F)ccc12 Show InChI InChI=1S/C10H10FN5/c1-5-7-3-2-6(11)4-8(7)15-10(14-5)16-9(12)13/h2-4H,1H3,(H4,12,13,14,15,16)	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Libre de Bruxelles Curated by ChEMBL					Assay Description Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 mins				J Med Chem 60: 6563-6586 (2017) Article DOI: 10.1021/acs.jmedchem.7b00285 BindingDB Entry DOI: 10.7270/Q27D2XD7
					More data for this Ligand-Target Pair
Lactoperoxidase (LPO) (Bos taurus (Bovine))	BDBM50238841 (CHEMBL4098162) Show SMILES CC(C)NCC(=O)c1nc2cc(F)ccc2[nH]1 Show InChI InChI=1S/C12H14FN3O/c1-7(2)14-6-11(17)12-15-9-4-3-8(13)5-10(9)16-12/h3-5,7,14H,6H2,1-2H3,(H,15,16)	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Libre de Bruxelles Curated by ChEMBL					Assay Description In vitro antagonist activity against rat prostatic androgen receptor (AR)				J Med Chem 60: 6563-6586 (2017) Article DOI: 10.1021/acs.jmedchem.7b00285 BindingDB Entry DOI: 10.7270/Q27D2XD7
					More data for this Ligand-Target Pair
Lactoperoxidase (LPO) (Bos taurus (Bovine))	BDBM48320 (4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...) Show SMILES CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC Show InChI InChI=1S/C14H22ClN3O2/c1-4-18(5-2)7-6-17-14(19)10-8-11(15)12(16)9-13(10)20-3/h8-9H,4-7,16H2,1-3H3,(H,17,19)	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Libre de Bruxelles Curated by ChEMBL					Assay Description Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 mins				J Med Chem 60: 6563-6586 (2017) Article DOI: 10.1021/acs.jmedchem.7b00285 BindingDB Entry DOI: 10.7270/Q27D2XD7
					More data for this Ligand-Target Pair
Lactoperoxidase (LPO) (Bos taurus (Bovine))	BDBM50238827 (CHEMBL4064328) Show SMILES Fc1ccc2[nH]c(nc2c1)[C@@H]1CCN(CC2NC=CN2)C1 Show InChI InChI=1S/C15H18FN5/c16-11-1-2-12-13(7-11)20-15(19-12)10-3-6-21(8-10)9-14-17-4-5-18-14/h1-2,4-5,7,10,14,17-18H,3,6,8-9H2,(H,19,20)/t10-/m1/s1	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Libre de Bruxelles Curated by ChEMBL					Assay Description Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 mins				J Med Chem 60: 6563-6586 (2017) Article DOI: 10.1021/acs.jmedchem.7b00285 BindingDB Entry DOI: 10.7270/Q27D2XD7
					More data for this Ligand-Target Pair
Lactoperoxidase (LPO) (Bos taurus (Bovine))	BDBM50489048 (CHEMBL2299190) Show SMILES S=c1oc(cc2ccccc12)-c1cccc2ccccc12 Show InChI InChI=1S/C19H12OS/c21-19-16-10-4-2-7-14(16)12-18(20-19)17-11-5-8-13-6-1-3-9-15(13)17/h1-12H	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysis				Citation and Details Article DOI: 10.1007/s00044-013-0475-x BindingDB Entry DOI: 10.7270/Q28055GB
					More data for this Ligand-Target Pair
Lactoperoxidase (LPO) (Bos taurus (Bovine))	BDBM50489044 (CHEMBL2299191) Show SMILES S=c1oc(cc2ccccc12)C1CCCCC1 Show InChI InChI=1S/C15H16OS/c17-15-13-9-5-4-8-12(13)10-14(16-15)11-6-2-1-3-7-11/h4-5,8-11H,1-3,6-7H2	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysis				Citation and Details Article DOI: 10.1007/s00044-013-0475-x BindingDB Entry DOI: 10.7270/Q28055GB
					More data for this Ligand-Target Pair
Lactoperoxidase (LPO) (Bos taurus (Bovine))	BDBM7460 (2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chrome...) Show SMILES Oc1cc(O)c2c(c1)oc(-c1ccc(O)c(O)c1)c(O)c2=O Show InChI InChI=1S/C15H10O7/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6/h1-5,16-19,21H	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Libre de Bruxelles Curated by ChEMBL					Assay Description Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 mins				J Med Chem 60: 6563-6586 (2017) Article DOI: 10.1021/acs.jmedchem.7b00285 BindingDB Entry DOI: 10.7270/Q27D2XD7
					More data for this Ligand-Target Pair
Lactoperoxidase (LPO) (Bos taurus (Bovine))	BDBM50489043 (CHEMBL2299192) Show SMILES Cc1ccc(cc1)-c1cc2ccccc2c(=S)o1 Show InChI InChI=1S/C16H12OS/c1-11-6-8-12(9-7-11)15-10-13-4-2-3-5-14(13)16(18)17-15/h2-10H,1H3	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article	n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysis				Citation and Details Article DOI: 10.1007/s00044-013-0475-x BindingDB Entry DOI: 10.7270/Q28055GB
					More data for this Ligand-Target Pair
Lactoperoxidase (LPO) (Bos taurus (Bovine))	BDBM217354 (2-(3,5-bistrifluoromethylbenzylamino)-6-oxo-1H-pyr...) Show SMILES ONC(=O)c1cnc(NCc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[nH]c1=O Show InChI InChI=1S/C14H10F6N4O3/c15-13(16,17)7-1-6(2-8(3-7)14(18,19)20)4-21-12-22-5-9(10(25)23-12)11(26)24-27/h1-3,5,27H,4H2,(H,24,26)(H2,21,22,23,25)	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	Purchase PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Otago Christchurch					Assay Description The halogenation activities of LPO (EC 1.11.1.7) and TPO (EC 1.11.1.8) were determined using a modified method of that described previously [Ferrari ...				J Biol Chem 288: 36636-47 (2013) Article DOI: 10.1074/jbc.M113.507756 BindingDB Entry DOI: 10.7270/Q20K27DH
					More data for this Ligand-Target Pair
Lactoperoxidase (Homo sapiens (Human))	BDBM50507390 (CHEMBL4482878 | US10981879, Example 3) Show SMILES Nc1cc(SCc2ccccc2F)c2nn[nH]c2n1 Show InChI InChI=1S/C12H10FN5S/c13-8-4-2-1-3-7(8)6-19-9-5-10(14)15-12-11(9)16-18-17-12/h1-5H,6H2,(H3,14,15,16,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human LPO assessed as reduction in H2O2 catalyzed 3,5-iodo tyrosine formation from 3-iodotyrosine and potassium iodide preincubated for...				ACS Med Chem Lett 9: 1175-1180 (2018) Article DOI: 10.1021/acsmedchemlett.8b00308
					More data for this Ligand-Target Pair
Lactoperoxidase (LPO) (Bos taurus (Bovine))	BDBM50241361 (CHEMBL1515 | METHIMAZOLE | US9138393, Methimazole ...) Show SMILES Cn1cc[nH]c1=S Show InChI InChI=1S/C4H6N2S/c1-6-3-2-5-4(6)7/h2-3H,1H3,(H,5,7)	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents	PDB Article	n/a	n/a	8.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysis				Citation and Details Article DOI: 10.1007/s00044-013-0475-x BindingDB Entry DOI: 10.7270/Q28055GB
					More data for this Ligand-Target Pair				3D Structure (crystal)
Lactoperoxidase (LPO) (Bos taurus (Bovine))	BDBM50489045 (CHEMBL2299193) Show SMILES COc1ccc(cc1)-c1cc2ccccc2c(=S)o1 Show InChI InChI=1S/C16H12O2S/c1-17-13-8-6-11(7-9-13)15-10-12-4-2-3-5-14(12)16(19)18-15/h2-10H,1H3	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article	n/a	n/a	8.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysis				Citation and Details Article DOI: 10.1007/s00044-013-0475-x BindingDB Entry DOI: 10.7270/Q28055GB
					More data for this Ligand-Target Pair
Lactoperoxidase (Homo sapiens (Human))	BDBM50275890 (CHEMBL457523 | ethyl 2,3-dihydro-3-methyl-2-seleno...) Show SMILES CCOC(=O)n1ccn(C)[c]1=[Se] Show InChI InChI=1S/C7H10N2O2Se/c1-3-11-7(10)9-5-4-8(2)6(9)12/h4-5H,3H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science Curated by ChEMBL					Assay Description Inhibition of lactoperoxidase (unknown origin)-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLC				J Med Chem 51: 7313-7 (2009) Article DOI: 10.1021/jm800894m BindingDB Entry DOI: 10.7270/Q2Z31ZGK
					More data for this Ligand-Target Pair
Lactoperoxidase (Homo sapiens (Human))	BDBM50275889 (CHEMBL508102 | carbimazole) Show SMILES CCOC(=O)n1ccn(C)c1=S Show InChI InChI=1S/C7H10N2O2S/c1-3-11-7(10)9-5-4-8(2)6(9)12/h4-5H,3H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.04E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science Curated by ChEMBL					Assay Description Inhibition of lactoperoxidase (unknown origin)-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLC				J Med Chem 51: 7313-7 (2009) Article DOI: 10.1021/jm800894m BindingDB Entry DOI: 10.7270/Q2Z31ZGK
					More data for this Ligand-Target Pair
Lactoperoxidase (Homo sapiens (Human))	BDBM50275891 (CHEMBL444464 | methyl 3-methyl-2-thioxo-2,3-dihydr...) Show SMILES COC(=O)n1ccn(C)c1=S Show InChI InChI=1S/C6H8N2O2S/c1-7-3-4-8(5(7)11)6(9)10-2/h3-4H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.07E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science Curated by ChEMBL					Assay Description Inhibition of lactoperoxidase (unknown origin)-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLC				J Med Chem 51: 7313-7 (2009) Article DOI: 10.1021/jm800894m BindingDB Entry DOI: 10.7270/Q2Z31ZGK
					More data for this Ligand-Target Pair
Lactoperoxidase (Homo sapiens (Human))	BDBM50241361 (CHEMBL1515 | METHIMAZOLE | US9138393, Methimazole ...) Show SMILES Cn1cc[nH]c1=S Show InChI InChI=1S/C4H6N2S/c1-6-3-2-5-4(6)7/h2-3H,1H3,(H,5,7)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	1.18E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science Curated by ChEMBL					Assay Description Inhibition of lactoperoxidase (unknown origin)-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLC				J Med Chem 51: 7313-7 (2009) Article DOI: 10.1021/jm800894m BindingDB Entry DOI: 10.7270/Q2Z31ZGK
					More data for this Ligand-Target Pair
Lactoperoxidase (LPO) (Bos taurus (Bovine))	BDBM50489042 (CHEMBL2295876) Show SMILES S=c1oc(cc2ccccc12)-c1ccccc1 Show InChI InChI=1S/C15H10OS/c17-15-13-9-5-4-8-12(13)10-14(16-15)11-6-2-1-3-7-11/h1-10H	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	Purchase PC cid PC sid UniChem	Article	n/a	n/a	1.39E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysis				Citation and Details Article DOI: 10.1007/s00044-013-0475-x BindingDB Entry DOI: 10.7270/Q28055GB
					More data for this Ligand-Target Pair
Lactoperoxidase (LPO) (Bos taurus (Bovine))	BDBM50489049 (CHEMBL2299195) Show SMILES S=c1oc(cc2ccccc12)-c1cccs1 Show InChI InChI=1S/C13H8OS2/c15-13-10-5-2-1-4-9(10)8-11(14-13)12-6-3-7-16-12/h1-8H	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article	n/a	n/a	1.43E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysis				Citation and Details Article DOI: 10.1007/s00044-013-0475-x BindingDB Entry DOI: 10.7270/Q28055GB
					More data for this Ligand-Target Pair
Lactoperoxidase (LPO) (Bos taurus (Bovine))	BDBM50489046 (CHEMBL2299198) Show SMILES CCCCc1cc2ccccc2c(=S)o1 Show InChI InChI=1S/C13H14OS/c1-2-3-7-11-9-10-6-4-5-8-12(10)13(15)14-11/h4-6,8-9H,2-3,7H2,1H3	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article	n/a	n/a	1.74E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysis				Citation and Details Article DOI: 10.1007/s00044-013-0475-x BindingDB Entry DOI: 10.7270/Q28055GB
					More data for this Ligand-Target Pair
Lactoperoxidase (LPO) (Bos taurus (Bovine))	BDBM50489041 (CHEMBL2299196) Show SMILES S=c1oc(cc2ccccc12)-c1ccco1 Show InChI InChI=1S/C13H8O2S/c16-13-10-5-2-1-4-9(10)8-12(15-13)11-6-3-7-14-11/h1-8H	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article	n/a	n/a	1.78E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysis				Citation and Details Article DOI: 10.1007/s00044-013-0475-x BindingDB Entry DOI: 10.7270/Q28055GB
					More data for this Ligand-Target Pair
Lactoperoxidase (LPO) (Bos taurus (Bovine))	BDBM7458 (5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one...) Show SMILES Oc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)cc2o1 Show InChI InChI=1S/C15H10O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-7,16-18H	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.78E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Libre de Bruxelles Curated by ChEMBL					Assay Description Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 mins				J Med Chem 60: 6563-6586 (2017) Article DOI: 10.1021/acs.jmedchem.7b00285 BindingDB Entry DOI: 10.7270/Q27D2XD7
					More data for this Ligand-Target Pair
Lactoperoxidase (Homo sapiens (Human))	BDBM50275895 (CHEMBL469530 | methyl 3-ethyl-2-thioxo-2,3-dihydro...) Show SMILES CCn1ccn(C(=O)OC)c1=S Show InChI InChI=1S/C7H10N2O2S/c1-3-8-4-5-9(6(8)12)7(10)11-2/h4-5H,3H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.96E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science Curated by ChEMBL					Assay Description Inhibition of lactoperoxidase (unknown origin)-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLC				J Med Chem 51: 7313-7 (2009) Article DOI: 10.1021/jm800894m BindingDB Entry DOI: 10.7270/Q2Z31ZGK
					More data for this Ligand-Target Pair
Lactoperoxidase (Homo sapiens (Human))	BDBM50275892 (CHEMBL507966 | methyl 3-methyl-2-selenoxo-2,3-dihy...) Show SMILES COC(=O)n1ccn(C)[c]1=[Se] Show InChI InChI=1S/C6H8N2O2Se/c1-7-3-4-8(5(7)11)6(9)10-2/h3-4H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.97E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science Curated by ChEMBL					Assay Description Inhibition of lactoperoxidase (unknown origin)-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLC				J Med Chem 51: 7313-7 (2009) Article DOI: 10.1021/jm800894m BindingDB Entry DOI: 10.7270/Q2Z31ZGK
					More data for this Ligand-Target Pair
Lactoperoxidase (Homo sapiens (Human))	BDBM50275893 (CHEMBL469529 | ethyl 3-ethyl-2-thioxo-2,3-dihydro-...) Show SMILES CCOC(=O)n1ccn(CC)c1=S Show InChI InChI=1S/C8H12N2O2S/c1-3-9-5-6-10(7(9)13)8(11)12-4-2/h5-6H,3-4H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science Curated by ChEMBL					Assay Description Inhibition of lactoperoxidase (unknown origin)-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLC				J Med Chem 51: 7313-7 (2009) Article DOI: 10.1021/jm800894m BindingDB Entry DOI: 10.7270/Q2Z31ZGK
					More data for this Ligand-Target Pair
Lactoperoxidase (Homo sapiens (Human))	BDBM50275894 (CHEMBL446332 | ethyl 3-ethyl-2-selenoxo-2,3-dihydr...) Show SMILES CCOC(=O)n1ccn(CC)[c]1=[Se] Show InChI InChI=1S/C8H12N2O2Se/c1-3-9-5-6-10(7(9)13)8(11)12-4-2/h5-6H,3-4H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.13E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science Curated by ChEMBL					Assay Description Inhibition of lactoperoxidase (unknown origin)-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLC				J Med Chem 51: 7313-7 (2009) Article DOI: 10.1021/jm800894m BindingDB Entry DOI: 10.7270/Q2Z31ZGK
					More data for this Ligand-Target Pair
Lactoperoxidase (LPO) (Bos taurus (Bovine))	BDBM50489039 (CHEMBL2299199) Show SMILES CC(C)(C)c1cc2ccccc2c(=S)o1 Show InChI InChI=1S/C13H14OS/c1-13(2,3)11-8-9-6-4-5-7-10(9)12(15)14-11/h4-8H,1-3H3	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article	n/a	n/a	2.19E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysis				Citation and Details Article DOI: 10.1007/s00044-013-0475-x BindingDB Entry DOI: 10.7270/Q28055GB
					More data for this Ligand-Target Pair
Lactoperoxidase (Homo sapiens (Human))	BDBM50275944 (CHEMBL459114 | methyl 3-ethyl-2-selenoxo-2,3-dihyd...) Show SMILES CCn1ccn(C(=O)OC)[c]1=[Se] Show InChI InChI=1S/C7H10N2O2Se/c1-3-8-4-5-9(6(8)12)7(10)11-2/h4-5H,3H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.53E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Science Curated by ChEMBL					Assay Description Inhibition of lactoperoxidase (unknown origin)-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLC				J Med Chem 51: 7313-7 (2009) Article DOI: 10.1021/jm800894m BindingDB Entry DOI: 10.7270/Q2Z31ZGK
					More data for this Ligand-Target Pair
Lactoperoxidase (LPO) (Bos taurus (Bovine))	BDBM50489047 (CHEMBL2299194) Show SMILES Clc1ccc(cc1)-c1cc2ccccc2c(=S)o1 Show InChI InChI=1S/C15H9ClOS/c16-12-7-5-10(6-8-12)14-9-11-3-1-2-4-13(11)15(18)17-14/h1-9H	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article	n/a	n/a	2.64E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysis				Citation and Details Article DOI: 10.1007/s00044-013-0475-x BindingDB Entry DOI: 10.7270/Q28055GB
					More data for this Ligand-Target Pair
Lactoperoxidase (LPO) (Bos taurus (Bovine))	BDBM50489040 (CHEMBL2299197) Show SMILES S=c1oc(cc2ccccc12)-c1ccoc1 Show InChI InChI=1S/C13H8O2S/c16-13-11-4-2-1-3-9(11)7-12(15-13)10-5-6-14-8-10/h1-8H	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article	n/a	n/a	2.65E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysis				Citation and Details Article DOI: 10.1007/s00044-013-0475-x BindingDB Entry DOI: 10.7270/Q28055GB
					More data for this Ligand-Target Pair
Lactoperoxidase (LPO) (Bos taurus (Bovine))	BDBM50489038 (CHEMBL2299200) Show SMILES O=c1oc(cc2ccccc12)-c1cccc2ccccc12 Show InChI InChI=1S/C19H12O2/c20-19-16-10-4-2-7-14(16)12-18(21-19)17-11-5-8-13-6-1-3-9-15(13)17/h1-12H	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article	n/a	n/a	3.46E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysis				Citation and Details Article DOI: 10.1007/s00044-013-0475-x BindingDB Entry DOI: 10.7270/Q28055GB
					More data for this Ligand-Target Pair
Lactoperoxidase (Homo sapiens (Human))	BDBM50554034 (CHEMBL4747269) Show SMILES Nc1cc([C@H](CCN[C@H]2C[C@H](c3ccccc23)c2ccccc2)c2ccccc2)c2nn[nH]c2n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid PDB UniChem	PubMed	n/a	n/a	>6.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of LPO (unknown origin)				Bioorg Med Chem 28: (2020)
					More data for this Ligand-Target Pair
Lactoperoxidase (Homo sapiens (Human))	BDBM50554035 (CHEMBL4790231) Show SMILES Nc1cc([C@H](CCNC23CCC(CC2)(CC3)c2ccccc2)c2ccccc2)c2nn[nH]c2n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid PDB UniChem	PubMed	n/a	n/a	>6.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of LPO (unknown origin)				Bioorg Med Chem 28: (2020)
					More data for this Ligand-Target Pair
Lactoperoxidase (LPO) (Bos taurus (Bovine))	BDBM50489050 (CHEMBL2299201) Show SMILES Cc1ccc(cc1)-c1cc2ccccc2c(=O)o1 Show InChI InChI=1S/C16H12O2/c1-11-6-8-12(9-7-11)15-10-13-4-2-3-5-14(13)16(17)18-15/h2-10H,1H3	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article	n/a	n/a	9.38E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysis				Citation and Details Article DOI: 10.1007/s00044-013-0475-x BindingDB Entry DOI: 10.7270/Q28055GB
					More data for this Ligand-Target Pair
Lactoperoxidase (Homo sapiens (Human))	BDBM50106515 (7-Benzyloxy-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-y...) Show SMILES Nc1nc(OCc2ccccc2)c2[nH]nnc2n1 Show InChI InChI=1S/C11H10N6O/c12-11-13-9-8(15-17-16-9)10(14-11)18-6-7-4-2-1-3-5-7/h1-5H,6H2,(H3,12,13,14,15,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar	CHEMBL PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human LPO assessed as reduction in H2O2 catalyzed 3,5-iodo tyrosine formation from 3-iodotyrosine and potassium iodide preincubated for...				ACS Med Chem Lett 9: 1175-1180 (2018) Article DOI: 10.1021/acsmedchemlett.8b00308
					More data for this Ligand-Target Pair
Lactoperoxidase (LPO) (Bos taurus (Bovine))	BDBM50489036 (CHEMBL2299202) Show SMILES Clc1ccc(cc1)-c1cc2ccccc2c(=O)o1 Show InChI InChI=1S/C15H9ClO2/c16-12-7-5-10(6-8-12)14-9-11-3-1-2-4-13(11)15(17)18-14/h1-9H	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article	n/a	n/a	1.05E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysis				Citation and Details Article DOI: 10.1007/s00044-013-0475-x BindingDB Entry DOI: 10.7270/Q28055GB
					More data for this Ligand-Target Pair
Lactoperoxidase (LPO) (Bos taurus (Bovine))	BDBM50207306 (CHEMBL2140153) Show SMILES O=c1oc(cc2ccccc12)-c1ccccc1 Show InChI InChI=1S/C15H10O2/c16-15-13-9-5-4-8-12(13)10-14(17-15)11-6-2-1-3-7-11/h1-10H	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysis				Citation and Details Article DOI: 10.1007/s00044-013-0475-x BindingDB Entry DOI: 10.7270/Q28055GB
					More data for this Ligand-Target Pair
Lactoperoxidase (LPO) (Bos taurus (Bovine))	BDBM114830 (3-(4-methoxyphenyl)-1H-isochromen-1-one | 3-(4-met...) Show SMILES COc1ccc(cc1)-c1cc2ccccc2c(=O)o1 Show InChI InChI=1S/C16H12O3/c1-18-13-8-6-11(7-9-13)15-10-12-4-2-3-5-14(12)16(17)19-15/h2-10H,1H3	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	Purchase PC cid PC sid UniChem Similars	Article	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysis				Citation and Details Article DOI: 10.1007/s00044-013-0475-x BindingDB Entry DOI: 10.7270/Q28055GB
					More data for this Ligand-Target Pair
Lactoperoxidase (LPO) (Bos taurus (Bovine))	BDBM50489037 (CHEMBL2299203) Show SMILES O=c1oc(cc2ccccc12)-c1ccco1 Show InChI InChI=1S/C13H8O3/c14-13-10-5-2-1-4-9(10)8-12(16-13)11-6-3-7-15-11/h1-8H	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	Article	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysis				Citation and Details Article DOI: 10.1007/s00044-013-0475-x BindingDB Entry DOI: 10.7270/Q28055GB
					More data for this Ligand-Target Pair