Compile Data Set for Download or QSAR
maximum 50k data
Found 7 Enz. Inhib. hit(s) with all data for entry = 1378
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Homo sapiens (Human))
Teligene

US Patent
LigandPNGBDBM318958(N-(5-(2,6-dimorpholinopyrimidin-4-yl)-4-(trifluoro...)
Affinity DataIC50:  0.400nMAssay Description:An in vitro assay which determines the ability of a test compound to inhibit PI3K alpha activity: PI3 alpha (PIK3CA) kinase-tagged T7 phage strains w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Homo sapiens (Human))
Teligene

US Patent
LigandPNGBDBM319549(US10173995, Compound 9)
Affinity DataIC50:  0.840nMAssay Description:An in vitro assay which determines the ability of a test compound to inhibit PI3K alpha activity: PI3 alpha (PIK3CA) kinase-tagged T7 phage strains w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Homo sapiens (Human))
Teligene

US Patent
LigandPNGBDBM318959(5-(2,6-dimorpholinopyrimidin-4-yl)-N-methyl-4-(tri...)
Affinity DataIC50:  1.90nMAssay Description:An in vitro assay which determines the ability of a test compound to inhibit PI3K alpha activity: PI3 alpha (PIK3CA) kinase-tagged T7 phage strains w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Homo sapiens (Human))
Teligene

US Patent
LigandPNGBDBM318960(5-(2,6-dimorpholinopyrimidin-4-yl)-N-ethyl-4-(trif...)
Affinity DataIC50:  10nMAssay Description:An in vitro assay which determines the ability of a test compound to inhibit PI3K alpha activity: PI3 alpha (PIK3CA) kinase-tagged T7 phage strains w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Homo sapiens (Human))
Teligene

US Patent
LigandPNGBDBM318958(N-(5-(2,6-dimorpholinopyrimidin-4-yl)-4-(trifluoro...)
Affinity DataIC50:  32nMAssay Description:An in vitro assay which determines the ability of a test compound to inhibit PI3K alpha activity: PI3 delta (PIK3CD) kinase-tagged T7 phage strains w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Homo sapiens (Human))
Teligene

US Patent
LigandPNGBDBM319548(US10173995, Compound 6)
Affinity DataIC50:  60nMAssay Description:An in vitro assay which determines the ability of a test compound to inhibit PI3K alpha activity: PI3 alpha (PIK3CA) kinase-tagged T7 phage strains w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Homo sapiens (Human))
Teligene

US Patent
LigandPNGBDBM50380363(CHEMBL2017974 | US10173995, Compound 1)
Affinity DataIC50:  310nMAssay Description:An in vitro assay which determines the ability of a test compound to inhibit PI3K alpha activity: PI3 delta (PIK3CD) kinase-tagged T7 phage strains w...More data for this Ligand-Target Pair
In DepthDetails US Patent