Compile Data Set for Download or QSAR
maximum 50k data
Found 53 Enz. Inhib. hit(s) with all data for entry = 2982
TargetInterleukin-2(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387262(N-(5′- (5,5-Dimethyl-4-oxo- 4,5-dihydroisoxa...)
Affinity DataIC50: <100nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-2(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387280(N-(2,6- Difluorophenyl)-5-(2- methyl-3-(4-methyl- ...)
Affinity DataIC50: <100nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-2(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387261(N-(5′- (5,5-Dimethyl-4-oxo- 4,5-dihydroisoxa...)
Affinity DataIC50: <100nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-2(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387264(N-(3′- (5,5-Dimethyl-4-oxo- 4,5-dihydroisoxa...)
Affinity DataIC50: <100nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-2(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387265(2,6- Difluoro-N-(2′- methyl-5′-(4-meth...)
Affinity DataIC50: <100nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-2(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387266(N-(5′- (4-Ethyl-5-oxo-4,5- dihydro-1,3,4- ...)
Affinity DataIC50: <100nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-2(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387267(2,6- Difluoro-N-(2′- methoxy-5′-(4- me...)
Affinity DataIC50: <100nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-2(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387268(N-(2′- Chloro-5′-(4-methyl- 5-oxo-4,5-...)
Affinity DataIC50: <100nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-2(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387269(2- Chloro-N-(5-(5-(5,5- dimethyl-4-oxo-4,5- dihydr...)
Affinity DataIC50: <100nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-2(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387270(2,6- Difluoro-N-(5-(2- methyl-5-(4- methyl-5-oxo-4...)
Affinity DataIC50: <100nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-2(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387271(2,6- Difluoro-N-(5-(2- methoxy-5-(4- methyl-5-oxo-...)
Affinity DataIC50: <100nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-2(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387272(N-(5-(5- (5,5-dimethyl-4-oxo- 4,5-dihydroisoxazol-...)
Affinity DataIC50: <100nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-2(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387273(US10292981, Example 135)
Affinity DataIC50: <100nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-2(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387274(N-(2,6- Difluorophenyl)-5-(5- (5,5-dimethyl-4-oxo-...)
Affinity DataIC50: <100nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-2(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387276(5-(5- (5,5-Dimethyl-4-oxo- 4,5-dihydroisoxazol- 3-...)
Affinity DataIC50: <100nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-2(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387277(N-(2,6- Difluorophenyl)-5-(5- (5,5-dimethyl-4-oxo-...)
Affinity DataIC50: <100nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-2(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387278(N-(2,6- Difluorophenyl)-5-(2- ethyl-5-(4-methyl-5-...)
Affinity DataIC50: <100nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-2(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387279(5-(2- (Difluoromethoxy)-5- (4-methyl-5-oxo-4,5- di...)
Affinity DataIC50: <100nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-2(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387263(N-(2′- acetamido-5′-(5,5- dimethyl-4-o...)
Affinity DataIC50: <100nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear factor of activated T-cells, cytoplasmic 2(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387273(US10292981, Example 135)
Affinity DataIC50: <500nMAssay Description:HEK 293 cells were stably transfected with a NFAT-Luc reporter gene. 30,000-80,000 cells were seeded per well. Test compounds from this invention wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear factor of activated T-cells, cytoplasmic 2(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387280(N-(2,6- Difluorophenyl)-5-(2- methyl-3-(4-methyl- ...)
Affinity DataIC50: <500nMAssay Description:HEK 293 cells were stably transfected with a NFAT-Luc reporter gene. 30,000-80,000 cells were seeded per well. Test compounds from this invention wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear factor of activated T-cells, cytoplasmic 2(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387315(4- Methyl-N-(2′-methyl- 3′-(4-methyl-5...)
Affinity DataIC50: <500nMAssay Description:HEK 293 cells were stably transfected with a NFAT-Luc reporter gene. 30,000-80,000 cells were seeded per well. Test compounds from this invention wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear factor of activated T-cells, cytoplasmic 2(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387264(N-(3′- (5,5-Dimethyl-4-oxo- 4,5-dihydroisoxa...)
Affinity DataIC50: <500nMAssay Description:HEK 293 cells were stably transfected with a NFAT-Luc reporter gene. 30,000-80,000 cells were seeded per well. Test compounds from this invention wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-2(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387285(N-(6-(5- (5,5-dimethyl-4-oxo- 4,5-dihydroisoxazol-...)
Affinity DataIC50:  550nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-2(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387281(N-(5-(5- (5,5-Dimethyl-4-oxo- 4,5-dihydroisoxazol-...)
Affinity DataIC50:  550nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-2(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387287(2,6- Difluoro-N-(5′-(4- methoxy-5,5- dimethy...)
Affinity DataIC50:  550nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-2(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387288(N-(3′- (5,5-Dimethyl-4-oxo- 4,5-dihydroisoxa...)
Affinity DataIC50:  550nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-2(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387289(N-(5-(5- (5,5-dimethyl-4-oxo- 4,5-dihydroisoxazol-...)
Affinity DataIC50:  550nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-2(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387290(N-(5- (5,5-Dimethyl-4,5- dihydroisoxazol-3- yl)-2-...)
Affinity DataIC50:  550nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-2(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387291(2,6- Difluoro-N-(2′- methyl-5′-(4-oxo-...)
Affinity DataIC50:  550nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-2(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387292(N-(5′- (4,4-dimethyl-4,5- dihydrooxazol-2-y...)
Affinity DataIC50:  550nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-2(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387293(N-(5-(5- (5,5-Dimethyl-4-oxo- 4,5-dihydroisoxazol-...)
Affinity DataIC50:  550nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-2(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387294(US10292981, Example 78)
Affinity DataIC50:  550nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-2(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387295(3,5- Dichloro-N-(5-(5-(5,5- dimethyl-4-oxo-4,5- di...)
Affinity DataIC50:  550nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-2(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387296(N-(5-(5- (5,5-dimethyl-4-oxo- 4,5-dihydroisoxazol-...)
Affinity DataIC50:  550nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-2(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387297(US10292981, Example 121)
Affinity DataIC50:  550nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-2(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387299(N-(5-(5- (5,5-dimethyl-4-oxo- 4,5-dihydroisoxazol-...)
Affinity DataIC50:  550nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-2(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387301(N-(2′- (allyloxy)-5′-(5,5- dimethyl-4-...)
Affinity DataIC50:  550nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-2(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387306(US10292981, Example 136)
Affinity DataIC50:  550nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-2(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387307(US10292981, Example 138)
Affinity DataIC50:  550nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-2(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387286(2,6- difluoro-N-(5-(5-(4- methoxy-5,5- dimethyl-4,...)
Affinity DataIC50:  550nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-2(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387282(N-(6-(5- (5,5-dimethyl-4-oxo- 4,5-dihydroisoxazol-...)
Affinity DataIC50:  550nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-2(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387283(N-(5-(5- (5,5-dimethyl-4-oxo- 4,5-dihydroisoxazol-...)
Affinity DataIC50:  550nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-2(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387284(N-(2′- chloro-5′-(5,5- dimethyl-4-oxo-...)
Affinity DataIC50:  550nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetStore-operated calcium entry-associated regulatory factor(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387313(N-(5′- (5,5-dimethyl-4-oxo- 4,5-dihydroisox...)
Affinity DataIC50: <1.00E+3nMAssay Description:Jurkat E6.1 cells were seeded at a density of 1-2×105 cells per well in calcium-4 dye prepared in calcium free HBSS (Sigma, USA). Test compounds from...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetStore-operated calcium entry-associated regulatory factor(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387314(2- Chloro-6-fluoro-N- (2′-methoxy-5′-(...)
Affinity DataIC50: <1.00E+3nMAssay Description:Jurkat E6.1 cells were seeded at a density of 1-2×105 cells per well in calcium-4 dye prepared in calcium free HBSS (Sigma, USA). Test compounds from...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetStore-operated calcium entry-associated regulatory factor(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387273(US10292981, Example 135)
Affinity DataIC50: <1.00E+3nMAssay Description:Jurkat E6.1 cells were seeded at a density of 1-2×105 cells per well in calcium-4 dye prepared in calcium free HBSS (Sigma, USA). Test compounds from...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetStore-operated calcium entry-associated regulatory factor(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387277(N-(2,6- Difluorophenyl)-5-(5- (5,5-dimethyl-4-oxo-...)
Affinity DataIC50: <1.00E+3nMAssay Description:Jurkat E6.1 cells were seeded at a density of 1-2×105 cells per well in calcium-4 dye prepared in calcium free HBSS (Sigma, USA). Test compounds from...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-2(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387308(N-(2′- (tert-butyl)-5′-(5,5- dimethyl-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-2(Homo sapiens (Human))
Lupin

US Patent
LigandPNGBDBM387312(2,6- Difluoro-N-(5′-(5-(2- hydroxyethyl)-5- ...)
Affinity DataIC50: >1.00E+3nMAssay Description:Jurkat T cells were seeded at a density of 0.5 to 1 million cells per well in RPMI medium. Test compounds from this invention were added to the cells...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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