Compile Data Set for Download or QSAR
maximum 50k data
Found 15 Enz. Inhib. hit(s) with all data for entry = 3262
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Syros Pharmaceuticals

US Patent
LigandPNGBDBM395706((+/−)-4-amino-N-(3-(5-chloro-4-(1H-indol-3-y...)
Affinity DataIC50: <100nMAssay Description:Compounds of the invention were assayed for CDK7 activity at Life Technologies (Grand Island, N.Y.) using their commercially available Adapta kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Syros Pharmaceuticals

US Patent
LigandPNGBDBM395712(4-amino-N-((1S,3R)-3-(5-cyano-4-(1H-indol-3-yl)pyr...)
Affinity DataIC50: <100nMAssay Description:Compounds of the invention were assayed for CDK7 activity at Life Technologies (Grand Island, N.Y.) using their commercially available Adapta kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Syros Pharmaceuticals

US Patent
LigandPNGBDBM395711( (1S,3R)—N-(4-aminophenyl)-3-(5-chloro-4-(1H-indol...)
Affinity DataIC50: <100nMAssay Description:Compounds of the invention were assayed for CDK7 activity at Life Technologies (Grand Island, N.Y.) using their commercially available Adapta kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Syros Pharmaceuticals

US Patent
LigandPNGBDBM395710(N-((1S,3R)-3-((5-chloro-4-(1H-indol-3-yl)pyrimidin...)
Affinity DataIC50: <100nMAssay Description:Compounds of the invention were assayed for CDK7 activity at Life Technologies (Grand Island, N.Y.) using their commercially available Adapta kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Syros Pharmaceuticals

US Patent
LigandPNGBDBM395709(4-amino-N-(5-(5-chloro-4-(1H-indol-3-yl)pyrimidin-...)
Affinity DataIC50:  550nMAssay Description:Compounds of the invention were assayed for CDK7 activity at Life Technologies (Grand Island, N.Y.) using their commercially available Adapta kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Syros Pharmaceuticals

US Patent
LigandPNGBDBM395716(4-amino-N-(1S,3R)-3-(5-chloro-4-(4H-indol-3-yl)pyr...)
Affinity DataIC50:  550nMAssay Description:Compounds of the invention were assayed for CDK7 activity at Life Technologies (Grand Island, N.Y.) using their commercially available Adapta kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Syros Pharmaceuticals

US Patent
LigandPNGBDBM395717(4-amino-N-((1S,3R)-3-(5-chloro-4-(1H-indol-3-yl)py...)
Affinity DataIC50:  550nMAssay Description:Compounds of the invention were assayed for CDK7 activity at Life Technologies (Grand Island, N.Y.) using their commercially available Adapta kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Syros Pharmaceuticals

US Patent
LigandPNGBDBM395718(N1-(4-(((1S,3R)-3-((5-chloro-4-(1H-indol-3-yl)pyri...)
Affinity DataIC50:  550nMAssay Description:Compounds of the invention were assayed for CDK7 activity at Life Technologies (Grand Island, N.Y.) using their commercially available Adapta kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Syros Pharmaceuticals

US Patent
LigandPNGBDBM395714(US10308648, Compound 109 | US10865206, Compound 10...)
Affinity DataIC50:  550nMAssay Description:Compounds of the invention were assayed for CDK7 activity at Life Technologies (Grand Island, N.Y.) using their commercially available Adapta kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Syros Pharmaceuticals

US Patent
LigandPNGBDBM395707(4-amino-N-((1S,3R)-3-(5-chloro-4-(1H-indol-3-yl)py...)
Affinity DataIC50:  550nMAssay Description:Compounds of the invention were assayed for CDK7 activity at Life Technologies (Grand Island, N.Y.) using their commercially available Adapta kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Syros Pharmaceuticals

US Patent
LigandPNGBDBM395708(4-amino-N-((1S,3R)-3-(5-cyclopropyl-4-(1H-indol-3-...)
Affinity DataIC50:  550nMAssay Description:Compounds of the invention were assayed for CDK7 activity at Life Technologies (Grand Island, N.Y.) using their commercially available Adapta kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Syros Pharmaceuticals

US Patent
LigandPNGBDBM395715((+/−)-4-amino-N-(3-(5-chloro-4-(1H-indol-3-y...)
Affinity DataIC50:  550nMAssay Description:Compounds of the invention were assayed for CDK7 activity at Life Technologies (Grand Island, N.Y.) using their commercially available Adapta kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Syros Pharmaceuticals

US Patent
LigandPNGBDBM395719(N-((1S,3R)-3-(4-(1H-indol-3-yl)pyrimidin-2-ylamino...)
Affinity DataIC50: >1.00E+3nMAssay Description:Compounds of the invention were assayed for CDK7 activity at Life Technologies (Grand Island, N.Y.) using their commercially available Adapta kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Syros Pharmaceuticals

US Patent
LigandPNGBDBM395705(4-amino-N-(3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Compounds of the invention were assayed for CDK7 activity at Life Technologies (Grand Island, N.Y.) using their commercially available Adapta kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Syros Pharmaceuticals

US Patent
LigandPNGBDBM395713(4-amino-N-((1S,3R)-3-(5-chloro-4-(pyridin-3-yl)pyr...)
Affinity DataIC50: >1.00E+3nMAssay Description:Compounds of the invention were assayed for CDK7 activity at Life Technologies (Grand Island, N.Y.) using their commercially available Adapta kinase ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent