Compile Data Set for Download or QSAR
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Found 7 Enz. Inhib. hit(s) with all data for entry = 8640
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM410042(1-[3-(4-Cyclopropylimidazol-1-yl)cyclobutyl]-3-[6-...)
Affinity DataIC50:  1.47nMAssay Description:The assay is done using an ADP-Glo Kinase Assay Kit (Promega, Catalog #V9102) according to the manufacturer's protocol with the following modific...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM410045(1-(3-(4-(tert-Butyl)-1H-imidazol-1-yl)cyclobutyl)-...)
Affinity DataIC50:  1.84nMAssay Description:The assay is done using an ADP-Glo Kinase Assay Kit (Promega, Catalog #V9102) according to the manufacturer's protocol with the following modific...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM410046(1-[3-(1-Isopropylpyrazol-4-yl)cyclobutyl]-3-[6-(4-...)
Affinity DataIC50:  2.17nMAssay Description:The assay is done using an ADP-Glo Kinase Assay Kit (Promega, Catalog #V9102) according to the manufacturer's protocol with the following modific...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM410044(1-[3-(3-Cyclopropyl-1,2,4-triazol-1-yl)cyclobutyl]...)
Affinity DataIC50:  2.56nMAssay Description:The assay is done using an ADP-Glo Kinase Assay Kit (Promega, Catalog #V9102) according to the manufacturer's protocol with the following modific...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM410043(1-(6-(4-Isopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-...)
Affinity DataIC50:  2.80nMAssay Description:The assay is done using an ADP-Glo Kinase Assay Kit (Promega, Catalog #V9102) according to the manufacturer's protocol with the following modific...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM410047(1-[6-(4-Isopropyl-1,2,4-triazol-3-yl)-2-pyridyl]-3...)
Affinity DataIC50:  5.26nMAssay Description:The assay is done using an ADP-Glo Kinase Assay Kit (Promega, Catalog #V9102) according to the manufacturer's protocol with the following modific...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM410048(1-(6-(4-Isopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-...)
Affinity DataIC50:  6.21nMAssay Description:The assay is done using an ADP-Glo Kinase Assay Kit (Promega, Catalog #V9102) according to the manufacturer's protocol with the following modific...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent