Compile Data Set for Download or QSAR
maximum 50k data
Found 104 Enz. Inhib. hit(s) with all data for entry = 8628
TargetBile acid receptor(Homo sapiens (Human))
Metacrine

US Patent
LigandPNGBDBM408870((E)-Methyl 3-(2-(N-((4′-(dimethylamino)-[1,1...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Metacrine

US Patent
LigandPNGBDBM408871((E)-Methyl 3-(6-(N-((4'-(dimethylamino)-[1,1'- bip...)
Affinity DataEC50: >1.00E+4nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Metacrine

US Patent
LigandPNGBDBM408872((E)-Methyl 3-(4-(N-((4'-(dimethylamino)-[1,1'- bip...)
Affinity DataEC50:  5.50E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Metacrine

US Patent
LigandPNGBDBM408873((E)-Methyl 3-(2-(N-((4'-(dimethylamino)-[1,1'- bip...)
Affinity DataEC50:  5.50E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Metacrine

US Patent
LigandPNGBDBM408874((E)-Methyl 3-(2-(N-(4-(6- (dimethylamino)pyridin-3...)
Affinity DataEC50:  5.50E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Metacrine

US Patent
LigandPNGBDBM408875((E)-Methyl 3-(2-(N-(4-(6- (dimethylamino)pyridin-3...)
Affinity DataEC50:  5.50E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Metacrine

US Patent
LigandPNGBDBM408876((E)-Methyl 3-(2-(trans-N-(4-(6- (dimethylamino) py...)
Affinity DataEC50:  5.50E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Metacrine

US Patent
LigandPNGBDBM408877(Methyl 5-(N-((4′-(dimethylamino)-[1,1′...)
Affinity DataEC50:  5.50E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Metacrine

US Patent
LigandPNGBDBM408878(N-((4'-(Dimethylamino)- [l,1'-biphenyl]-4- yl)meth...)
Affinity DataEC50: >1.00E+4nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Metacrine

US Patent
LigandPNGBDBM408879(Methyl 7-(N-((4'-(dimethylamino)-[1,1'- biphenyl]-...)
Affinity DataEC50: >1.00E+4nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Metacrine

US Patent
LigandPNGBDBM408880(Methyl 4-(N-((4'-(dimethylamino)-[1,1'- biphenyl]-...)
Affinity DataEC50: >1.00E+4nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Metacrine

US Patent
LigandPNGBDBM408881(Methyl 7-(N-((4'-(dimethylamino)-[1,1'- biphenyl]-...)
Affinity DataEC50:  5.50E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Metacrine

US Patent
LigandPNGBDBM408882(Methyl 1-(N-((4'-(dimethylamino)-[1,1'- biphenyl]-...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Metacrine

US Patent
LigandPNGBDBM408883(Ethyl 8-(N-((4'-(dimethylamino)-[1,1'- biphenyl]-4...)
Affinity DataEC50:  5.50E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Metacrine

US Patent
LigandPNGBDBM408884(Methyl 7-(N-((4'-(dimethylamino)-[1,1'- biphenyl]-...)
Affinity DataEC50: >1.00E+4nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Metacrine

US Patent
LigandPNGBDBM408885(Methyl 4-(N-((4'-(dimethylamino)-[1,1'- biphenyl]-...)
Affinity DataEC50: >1.00E+4nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Metacrine

US Patent
LigandPNGBDBM408886(Methyl 1-(N-((4'-(dimethylamino)-[1,1'- biphenyl]-...)
Affinity DataEC50:  5.50E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Metacrine

US Patent
LigandPNGBDBM408887((E)-Methyl 3-(2-(N-((trans-4-(4-methoxy-3-methylph...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Metacrine

US Patent
LigandPNGBDBM408888(Methyl 1-(N-((4′-methoxy-3′-methyl-[1,...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Metacrine

US Patent
LigandPNGBDBM408889(Methyl 1-(N-((4'-methoxy-3'-methyl-[1,1'- biphenyl...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Metacrine

US Patent
LigandPNGBDBM408890(Ethyl 1-(N-((4'-methoxy-3'-methyl-[1,1'- biphenyl]...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Metacrine

US Patent
LigandPNGBDBM408891(Isopropyl 1-(N-((4'-methoxy-3'-methyl-[1,1'- biphe...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Metacrine

US Patent
LigandPNGBDBM408892(Ethyl 5-(N-((4'-methoxy-3'-methyl-[1,1'- biphenyl]...)
Affinity DataEC50:  5.50E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Metacrine

US Patent
LigandPNGBDBM408893(Methyl 1-(N-((3'-cyano-4'-methoxy-[1,1'- biphenyl]...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Metacrine

US Patent
LigandPNGBDBM408894(Methyl 1-(N-((4'-methoxy-3'- methyl-[1,1'-biphenyl...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Metacrine

US Patent
LigandPNGBDBM408895(Methyl 1-(N-((2-cyano-4'-methoxy-3'- methyl- [1,1'...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Metacrine

US Patent
LigandPNGBDBM408896(Methyl 1-(N-((4'-methoxy-3'-methyl- [1,1'-biphenyl...)
Affinity DataEC50: >1.00E+4nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Metacrine

US Patent
LigandPNGBDBM408897(Methyl 1-(N-((4'-methoxy-3'-methyl- [1,1'-biphenyl...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Metacrine

US Patent
LigandPNGBDBM408898(Methyl 1-(N- ((2',3'-difluoro-4'-methoxy- [1,1'-bi...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Metacrine

US Patent
LigandPNGBDBM408899(Methyl 1-(N-((3'-cyano-4'-methyl-[1,1'- biphenyl]-...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Metacrine

US Patent
LigandPNGBDBM408900(Methyl 1-(N-((3'-chloro-4'-cyano-[1,1'- biphenyl]-...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Metacrine

US Patent
LigandPNGBDBM408901(Methyl 1-(N-((4'-chloro-3'-cyano-[1,1'- biphenyl]-...)
Affinity DataEC50:  5.50E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Metacrine

US Patent
LigandPNGBDBM408902(Methyl 1-(3,3-dimethyl-N-(4-(6- (trifluoromethyl)p...)
Affinity DataEC50:  5.50E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Metacrine

US Patent
LigandPNGBDBM408903(Methyl 1-(N-(4-(2,2- difluorobenzo[d][1,3] dioxol-...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Metacrine

US Patent
LigandPNGBDBM408904(Methyl 1-(N-(4-(5-fluoro-6- methoxypyridin-3- yl)b...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Metacrine

US Patent
LigandPNGBDBM408905(Methyl 1-(N-(4-(5-chloro-6- methoxypyridin-3- yl)b...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Metacrine

US Patent
LigandPNGBDBM408906(Methyl 1-(N-(4-(6-methoxy-5-methylpyridin-3- yl)be...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Metacrine

US Patent
LigandPNGBDBM408908(Methyl 1-(N-(4-(6-(dimethylamino)pyridin-3- yl)ben...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Metacrine

US Patent
LigandPNGBDBM408909(Methyl 1-(3,3-dimethyl-N-(4-(6-methylpyridin- 3-yl...)
Affinity DataEC50:  5.50E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Metacrine

US Patent
LigandPNGBDBM408910(Methyl 1-(N-((4'-cyclopropyl-[1,1'-biphenyl]-4- yl...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Metacrine

US Patent
LigandPNGBDBM408911(Methyl 1-(N-((3'-chloro-4'-(trifluoromethoxy)- [1,...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Metacrine

US Patent
LigandPNGBDBM408912(Methyl 1-(N-((4'-cyano-3'-methyl-[1,1'- biphenyl]-...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Metacrine

US Patent
LigandPNGBDBM408913(Methyl 1-(N-((4'-(hydroxymethyl)-[1,1'- biphenyl]-...)
Affinity DataEC50:  5.50E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Metacrine

US Patent
LigandPNGBDBM408914(Methyl 1-(3,3-dimethyl-N-(4-(1-methyl-1H- indol-5-...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Metacrine

US Patent
LigandPNGBDBM408915(Methyl 1-(N-((4'-methoxy-[1,1'-biphenyl]-4- yl)met...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Metacrine

US Patent
LigandPNGBDBM408916(Methyl 1-(N-(4-(2,3-dihydrobenzofuran-5- yl)benzyl...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Metacrine

US Patent
LigandPNGBDBM408917(Methyl 1-(N-(4-(2,3-dihydrobenzofuran-6- yl)benzyl...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Metacrine

US Patent
LigandPNGBDBM408918(Methyl 1-(N-(4-(2,3- dihydrobenzo[b][1,4] dioxin-6...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Metacrine

US Patent
LigandPNGBDBM408919(Methyl 1-(3,3-dimethyl-N-(4-(1-methyl-1H- pyrrolo[...)
Affinity DataEC50: <1.00E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBile acid receptor(Homo sapiens (Human))
Metacrine

US Patent
LigandPNGBDBM408920(Methyl 1-(3,3-dimethyl-N-(4-(2- methylbenzo[d]thia...)
Affinity DataEC50:  5.50E+3nMAssay Description:SeedingCV-1 cells were seeded at a density of 2,000,000 cells in a T175 flask with DMEM+10% charcoal double-stripped FBS and incubated at 37° C. in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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