Compile Data Set for Download or QSAR
maximum 50k data
Found 634 Enz. Inhib. hit(s) with all data for entry = 8633
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409275(2-[6-(4-Fluoro-3-methyl-phenyl)pyrrolo[3,2-b]pyrid...)
Affinity DataIC50:  2nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409513(2-[6-(5-Chloro-2-thienyl)pyrrolo[3,2-b]pyridin-1-y...)
Affinity DataIC50:  6.31nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409512(2-[6-[3-(Difluoromethyl)phenyl]pyrrolo[3,2-b]pyrid...)
Affinity DataIC50:  10nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409515(1-(Azetidin-1-yl)-2-[6-(5-methyl-2-thienyl)pyrrolo...)
Affinity DataIC50:  10nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409623(2-[6-(3-Chlorophenyl)-3-fluoro-pyrrolo[3,2-b]pyrid...)
Affinity DataIC50:  10nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409743(2-[6-(3,5-Difluorophenyl)-3-(trifluoromethyl)pyrro...)
Affinity DataIC50:  10nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409735(2-[3-Chloro-6-(5-chloro-4-methyl-2-thienyl)pyrrolo...)
Affinity DataIC50:  10nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409470(1-[3-Fluoro-6-(4-fluoro-3-methyl-phenyl)pyrrolo[3,...)
Affinity DataIC50:  12.6nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409474(1-[3-Fluoro-6-(4-methyl-2-thienyl)pyrrolo[3,2-b]py...)
Affinity DataIC50:  12.6nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409475(4-[6-(4-Fluorophenyl)pyrrolo[3,2-b]pyridin-1-yl]bu...)
Affinity DataIC50:  12.6nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409510(N,N-Dimethyl-2-[6-(3,4,5-trifluorophenyl)pyrrolo[3...)
Affinity DataIC50:  12.6nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409638(2-[6-(3-Chloro-4-fluoro-phenyl)-3-fluoro-pyrrolo[3...)
Affinity DataIC50:  12.6nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409678(2-[3-Chloro-6-(3-chlorophenyl)pyrrolo[3,2-b]pyridi...)
Affinity DataIC50:  12.6nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409598(N-Ethyl-2-[6-[2-fluoro-3-(trifluoromethyl)phenyl]p...)
Affinity DataIC50:  12.6nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409618(1-(3-Fluoroazetidin-1-yl)-2-[3-fluoro-6-[3- | US10...)
Affinity DataIC50:  12.6nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409629(2-(3-Fluoro-6-phenyl-pyrrolo[3,2-b]pyridin-1-yl)-N...)
Affinity DataIC50:  12.6nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409670(2-[3-Chloro-6-(3,5-difluorophenyl)pyrrolo[3,2-b]py...)
Affinity DataIC50:  12.6nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409516(1-(Azetidin-1-yl)-2-[3-chloro-6-(5-chloro-2-thieny...)
Affinity DataIC50:  15.8nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409640(1-(Azetidin-1-yl)-2-[3-fluoro-6-(3-fluorophenyl)py...)
Affinity DataIC50:  15.8nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409518(1-(Azetidin-1-yl)-2-[3-fluoro-6-(3,4,5-trifluoroph...)
Affinity DataIC50:  15.8nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409472(1-[6-[3-(Difluoromethyl)phenyl]-3-fluoro-pyrrolo[3...)
Affinity DataIC50:  15.8nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409473(1-[6-(5-Chloro-2-thienyl)-3-fluoro-pyrrolo[3,2-b]p...)
Affinity DataIC50:  15.8nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409485(N-Cyclopropyl-2-[6-(3,5-difluorophenyl)pyrrolo[3,2...)
Affinity DataIC50:  15.8nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409506(1-(3-Fluoroazetidin-1-yl)-2-[6-(3,4,5-trifluorophe...)
Affinity DataIC50:  15.8nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409507(2-[6-(5-Chloro-2-thienyl)pyrrolo[3,2-b]pyridin-1-y...)
Affinity DataIC50:  15.8nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409091(2-[3-Chloro-6-(3,4-difluorophenyl)pyrrolo[3,2-b]py...)
Affinity DataIC50:  15.8nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409755(2-[6-(3,5-Difluorophenyl)-3-methyl-pyrrolo[3,2-b]p...)
Affinity DataIC50:  15.8nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409591(1-(3-Fluoroazetidin-1-yl)-2-[6-(2-fluorophenyl)pyr...)
Affinity DataIC50:  15.8nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409602(2-[6-(3-Chloro-4-fluoro-phenyl)pyrrolo[3,2-b]pyrid...)
Affinity DataIC50:  15.8nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409603(2-[6-(2,4-Difluoro-3-methyl-phenyl)pyrrolo[3,2-b]p...)
Affinity DataIC50:  15.8nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409616(1-(3-Fluoroazetidin-1-yl)-2-(3-fluoro-6-phenyl-pyr...)
Affinity DataIC50:  15.8nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409622(2-[6-(2,4-Difluoro-3-methyl-phenyl)-3-fluoro-pyrro...)
Affinity DataIC50:  15.8nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409625(2-[6-(3-Ethylphenyl)-3-fluoro-pyrrolo[3,2-b]pyridi...)
Affinity DataIC50:  15.8nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409637(2-[6-(3-Chlorophenyl)-3-fluoro-pyrrolo[3,2-b]pyrid...)
Affinity DataIC50:  15.8nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409517(1-(Azetidin-1-yl)-2-[6-(3,4-difluorophenyl)-3-fluo...)
Affinity DataIC50:  15.8nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409519(2-[3-Chloro-6-(4-fluorophenyl)pyrrolo[3,2-b]pyridi...)
Affinity DataIC50:  20nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409641(1-(3-Fluoroazetidin-1-yl)-2-[3-fluoro-6-(2- | US10...)
Affinity DataIC50:  20nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409445(2-[3-Fluoro-6-(4-fluoro-3-methyl-phenyl)pyrrolo[3,...)
Affinity DataIC50:  20nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409450(2-[6-(5-Chloro-2-thienyl)-3-fluoro-pyrrolo[3,2-b]p...)
Affinity DataIC50:  20nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409451(1-Cyclopropyl-2-[3-fluoro-6-(4-fluorophenyl)pyrrol...)
Affinity DataIC50:  20nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409453(1-Cyclopropyl-2-[6-[3-(difluoromethyl)phenyl]-3-fl...)
Affinity DataIC50:  20nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409454(1-(Azetidin-1-yl)-2-[3-fluoro-6-(4-methyl-2-thieny...)
Affinity DataIC50:  20nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409471(1-[6-(3,4-Difluorophenyl)-3-fluoro-pyrrolo[3,2-b]p...)
Affinity DataIC50:  20nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409491(1-(Azetidin-1-yl)-2-[6-(m-tolyl)pyrrolo[3,2-b]pyri...)
Affinity DataIC50:  20nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409492(1-(Azetidin-1-yl)-2-[6-(3,4-dichlorophenyl)pyrrolo...)
Affinity DataIC50:  20nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409499(1-[6-(3,5-Difluorophenyl)pyrrolo[3,2-b]pyridin-1-y...)
Affinity DataIC50:  20nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409500(1-Cyclobutyl-2-[6-(4-fluorophenyl)pyrrolo[3,2-b]py...)
Affinity DataIC50:  20nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409504(2-[6-(4-Methyl-2-thienyl)pyrrolo[3,2-b]pyridin-1-y...)
Affinity DataIC50:  20nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409508(1-(Azetidin-1-yl)-2-[6-(5-chloro-2-thienyl)pyrrolo...)
Affinity DataIC50:  20nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM409509(2-[3-Chloro-6-(2,3,4-trifluorophenyl)pyrrolo[3,2-b...)
Affinity DataIC50:  20nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
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