Compile Data Set for Download or QSAR
maximum 50k data
Found 22 Enz. Inhib. hit(s) with all data for entry = 8801
TargetToll-like receptor 7(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50241029(1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quino...)
Affinity DataEC50:  420nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) r...More data for this Ligand-Target Pair
TargetInterleukin-6(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM420042(US10487084, Compound Ic-01)
Affinity DataEC50:  365nMAssay Description:Compounds diluted in DMSO were transferred to individual wells of a Matrix Tech-nologies clear, V-bottom 384-well plate using ECHO acoustic liquid ha...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50320067(1-(4-amino-2-((ethylamino)methyl)-1H-imidazo[4,5-c...)
Affinity DataEC50:  3.34E+3nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) r...More data for this Ligand-Target Pair
TargetToll-like receptor 7(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM419191(US10457681, Compound B | US10487084, Compound B | ...)
Affinity DataEC50:  474nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM419193(US10457681, Compound Ia-01 | US10487084, Compound ...)
Affinity DataEC50:  16nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-6(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM419193(US10457681, Compound Ia-01 | US10487084, Compound ...)
Affinity DataEC50:  108nMAssay Description:Compounds diluted in DMSO were transferred to individual wells of a Matrix Tech-nologies clear, V-bottom 384-well plate using ECHO acoustic liquid ha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM419194(US10457681, Compound Ia-02 | US10487084, Compound ...)
Affinity DataEC50:  5.90nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-6(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM419194(US10457681, Compound Ia-02 | US10487084, Compound ...)
Affinity DataEC50:  12.6nMAssay Description:Compounds diluted in DMSO were transferred to individual wells of a Matrix Tech-nologies clear, V-bottom 384-well plate using ECHO acoustic liquid ha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM419208(US10457681, Compound Ia-03 | US10487084, Compound ...)
Affinity DataEC50:  26nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-6(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM419208(US10457681, Compound Ia-03 | US10487084, Compound ...)
Affinity DataEC50:  15nMAssay Description:Compounds diluted in DMSO were transferred to individual wells of a Matrix Tech-nologies clear, V-bottom 384-well plate using ECHO acoustic liquid ha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM419219(US10457681, Compound Ia-04 | US10487084, Compound ...)
Affinity DataEC50:  7.5nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-6(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM419219(US10457681, Compound Ia-04 | US10487084, Compound ...)
Affinity DataEC50:  6.90nMAssay Description:Compounds diluted in DMSO were transferred to individual wells of a Matrix Tech-nologies clear, V-bottom 384-well plate using ECHO acoustic liquid ha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM419243(US10457681, Compound Ia-05 | US10487084, Compound ...)
Affinity DataEC50:  8nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-6(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM419243(US10457681, Compound Ia-05 | US10487084, Compound ...)
Affinity DataEC50:  39.7nMAssay Description:Compounds diluted in DMSO were transferred to individual wells of a Matrix Tech-nologies clear, V-bottom 384-well plate using ECHO acoustic liquid ha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM419258(US10457681, Compound Ia-06 | US10487084, Compound ...)
Affinity DataEC50:  24nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-6(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM419258(US10457681, Compound Ia-06 | US10487084, Compound ...)
Affinity DataEC50:  88.7nMAssay Description:Compounds diluted in DMSO were transferred to individual wells of a Matrix Tech-nologies clear, V-bottom 384-well plate using ECHO acoustic liquid ha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM420040(US10487084, Compound Ib-01)
Affinity DataEC50:  59nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) r...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetInterleukin-6(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM420040(US10487084, Compound Ib-01)
Affinity DataEC50:  106nMAssay Description:Compounds diluted in DMSO were transferred to individual wells of a Matrix Tech-nologies clear, V-bottom 384-well plate using ECHO acoustic liquid ha...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM420041(US10487084, Compound Ib-02)
Affinity DataEC50:  52nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) r...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetInterleukin-6(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM420041(US10487084, Compound Ib-02)
Affinity DataEC50:  7.55nMAssay Description:Compounds diluted in DMSO were transferred to individual wells of a Matrix Tech-nologies clear, V-bottom 384-well plate using ECHO acoustic liquid ha...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM420042(US10487084, Compound Ic-01)
Affinity DataEC50:  99nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) r...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50440284(CHEMBL2424780 | US10457681, Compound Vesatolimod |...)
Affinity DataEC50:  1.20E+3nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) r...More data for this Ligand-Target Pair