Compile Data Set for Download or QSAR
maximum 50k data
Found 12 Enz. Inhib. hit(s) with all data for entry = 8887
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
The Rockefeller University

US Patent
LigandPNGBDBM426493(US10543183, Compound SB742881 | US10669296, Compou...)
Affinity DataEC50:  25nMAssay Description:As used herein, reference to the activity of an LXR agonist at LXRα and LXRβ refer to the activity as measured using the ligand sensing ass...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
The Rockefeller University

US Patent
LigandPNGBDBM19993(CHEMBL62136 | N-[4-(1,1,1,3,3,3-hexafluoro-2-hydro...)
Affinity DataEC50:  50nMAssay Description:As used herein, reference to the activity of an LXR agonist at LXRα and LXRβ refer to the activity as measured using the ligand sensing ass...More data for this Ligand-Target Pair
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
The Rockefeller University

US Patent
LigandPNGBDBM50204072(CHEMBL3945199 | US10543183, Compound 12 | US109459...)
Affinity DataEC50:  11nMAssay Description:As used herein, reference to the activity of an LXR agonist at LXRα and LXRβ refer to the activity as measured using the ligand sensing ass...More data for this Ligand-Target Pair
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
The Rockefeller University

US Patent
LigandPNGBDBM50034775(CHEMBL3360975 | US10543183, Compound 38 | US109459...)
Affinity DataEC50:  550nMAssay Description:As used herein, reference to the activity of an LXR agonist at LXRα and LXRβ refer to the activity as measured using the ligand sensing ass...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
The Rockefeller University

US Patent
LigandPNGBDBM50034775(CHEMBL3360975 | US10543183, Compound 38 | US109459...)
Affinity DataEC50:  630nMAssay Description:As used herein, reference to the activity of an LXR agonist at LXRα and LXRβ refer to the activity as measured using the ligand sensing ass...More data for this Ligand-Target Pair
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
The Rockefeller University

US Patent
LigandPNGBDBM26066(2-[(2-chloro-4-fluorophenyl)methyl]-3-(4-fluorophe...)
Affinity DataEC50:  24nMAssay Description:As used herein, reference to the activity of an LXR agonist at LXRα and LXRβ refer to the activity as measured using the ligand sensing ass...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
The Rockefeller University

US Patent
LigandPNGBDBM19993(CHEMBL62136 | N-[4-(1,1,1,3,3,3-hexafluoro-2-hydro...)
Affinity DataEC50:  20nMAssay Description:As used herein, reference to the activity of an LXR agonist at LXRα and LXRβ refer to the activity as measured using the ligand sensing ass...More data for this Ligand-Target Pair
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
The Rockefeller University

US Patent
LigandPNGBDBM19992(2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methy...)
Affinity DataEC50:  200nMAssay Description:As used herein, reference to the activity of an LXR agonist at LXRα and LXRβ refer to the activity as measured using the ligand sensing ass...More data for this Ligand-Target Pair
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
The Rockefeller University

US Patent
LigandPNGBDBM19992(2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methy...)
Affinity DataEC50:  40nMAssay Description:As used herein, reference to the activity of an LXR agonist at LXRα and LXRβ refer to the activity as measured using the ligand sensing ass...More data for this Ligand-Target Pair
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
The Rockefeller University

US Patent
LigandPNGBDBM426493(US10543183, Compound SB742881 | US10669296, Compou...)
Affinity DataEC50:  74nMAssay Description:As used herein, reference to the activity of an LXR agonist at LXRα and LXRβ refer to the activity as measured using the ligand sensing ass...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
The Rockefeller University

US Patent
LigandPNGBDBM26066(2-[(2-chloro-4-fluorophenyl)methyl]-3-(4-fluorophe...)
Affinity DataEC50:  179nMAssay Description:As used herein, reference to the activity of an LXR agonist at LXRα and LXRβ refer to the activity as measured using the ligand sensing ass...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
The Rockefeller University

US Patent
LigandPNGBDBM50204072(CHEMBL3945199 | US10543183, Compound 12 | US109459...)
Affinity DataEC50: <100nMAssay Description:As used herein, reference to the activity of an LXR agonist at LXRα and LXRβ refer to the activity as measured using the ligand sensing ass...More data for this Ligand-Target Pair
In DepthDetails US Patent