Compile Data Set for Download or QSAR
maximum 50k data
Found 133 Enz. Inhib. hit(s) with all data for entry = 8905
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427143(1-({[(1R)-2-[(4-chloro-2-methanesulfonylphenyl)met...)
Affinity DataIC50:  0.490nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427127(1-({[(1R)-2-[(4-chloro-2-methanesulfonylphenyl)met...)
Affinity DataIC50:  0.5nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427196(US10544132, Example 137)
Affinity DataIC50:  0.570nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427156(4-{[(1R)-1-(4-chlorophenyl)-7-fluoro-5-[I-hydroxy-...)
Affinity DataIC50:  0.640nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427122(US10544132, Example 69 | US10981898, Example 70)
Affinity DataIC50:  0.700nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427147((3S)-3-(4-chlorophenyl)-3-[(1R)-1-(4-chlorophenyl)...)
Affinity DataIC50:  0.790nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427158((3S)-3-(4-chlorophenyl)-3-[(1R)-1-(4-chlorophenyl)...)
Affinity DataIC50:  0.800nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427098(US10544132, Example 50 | US10981898, Example 62 | ...)
Affinity DataIC50:  0.800nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427136((3R)-2-[(4-chloro-2-methanesulfonylphenyl)methyl]-...)
Affinity DataIC50:  1nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427193(US10544132, Example 134 | US11236047, Example 135)
Affinity DataIC50:  1.10nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427195(US10544132, Example 136 | US10981898, Example 137 ...)
Affinity DataIC50:  1.30nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427125(US10544132, Example 72 | US10981898, Example 72 | ...)
Affinity DataIC50:  1.5nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427086((3R)-2-[(4-chloro-2-methanesulfonylphenyl)methyl]-...)
Affinity DataIC50:  1.60nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427080(US10544132, Example 35)
Affinity DataIC50:  1.80nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427118((3R)-2-[(4-Chloro-2-methanesulfonylphenyl)methyl]-...)
Affinity DataIC50:  1.80nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427078(US10544132, Example 33 | US11236047, Example 33 | ...)
Affinity DataIC50:  1.90nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427185(US10544132, Example 126)
Affinity DataIC50:  1.90nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427081( (3R)-2-[(4-chloro-2-methanesulfonylphenyl)methyl]...)
Affinity DataIC50:  1.90nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427124(US10544132, Example 71 | US10981898, Example 71 | ...)
Affinity DataIC50:  2nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427117((3R)-2-[(4-Chloro-2-methanesulfonylphenyl)methyl]-...)
Affinity DataIC50:  2.10nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427132(US10544132, Example 79 | US11236047, Example 79 | ...)
Affinity DataIC50:  2.20nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427115((3R)-2-[(4-Chloro-2-methanesulfinylphenyl)methyl]-...)
Affinity DataIC50:  2.30nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427135(US10544132, Example 82 | US10981898, Example 82 | ...)
Affinity DataIC50:  2.5nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427134((3R)-2-[(4-chloro-2-methanesulfonylphenyl)methyl]-...)
Affinity DataIC50:  2.60nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427119((3R)-2-[(4-Chloro-2-methanesulfonylphenyl)methyl]-...)
Affinity DataIC50:  3nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427056((3R)-3-(4-chlorophenyl)-2-[(1S)-1-(4-chlorophenyl)...)
Affinity DataIC50:  3.70nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427110(2-[(1R)-1-(4-Chlorophenyl)-2-[(4-chlorophenyl)meth...)
Affinity DataIC50:  4.10nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427186((3S)-3-(4-chlorophenyl)-3-[(1R)-1-(4-chlorophenyl)...)
Affinity DataIC50:  4.5nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427131((3R)-2-[(4-chloro-2-methanesulfonylphenyl)methyl]-...)
Affinity DataIC50:  4.60nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427047(US10544132, Example 2 | US10981898, Example 2 | US...)
Affinity DataIC50:  4.60nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427079(US10544132, Example 34 | US11236047, Example 34 | ...)
Affinity DataIC50:  4.60nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427054((3R)-3-(4-chlorophenyl)-2-[(4-chlorophenyl)methyl]...)
Affinity DataIC50:  4.70nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427061(US10544132, Example 14 | US10981898, Example 14 | ...)
Affinity DataIC50:  5nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427069((3R)-3-(4-chlorophenyl)-6-(1,2-dihydroxypropan-2-y...)
Affinity DataIC50:  5.20nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427123(US10544132, Example 70 | US10981898, Example 69)
Affinity DataIC50:  5.70nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427089((3R)-2-[(4-chloro-2-methanesulfonylphenyl)methyl]-...)
Affinity DataIC50:  5.80nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427058((3R)-3-(4-chlorophenyl)-2-[(4-chlorophenyl)methyl]...)
Affinity DataIC50:  5.80nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427168(US10544132, Example 108 | US10981898, Example 108 ...)
Affinity DataIC50:  6.10nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427160(US10544132, Example 100 | US10981898, Example 100 ...)
Affinity DataIC50:  6.30nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427053(US10544132, Example 7 | US10981898, Example 7 | US...)
Affinity DataIC50:  6.60nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427121(US10544132, Example 68)
Affinity DataIC50:  7nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427071(US10544132, Example 25 | US10981898, Example 25 | ...)
Affinity DataIC50:  7.20nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427023(US10544132, Example 1 | US10544132, Example 48 | U...)
Affinity DataIC50:  7.30nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427068(US10544132, Example 21 | US10544132, Example 24 | ...)
Affinity DataIC50:  7.5nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427068(US10544132, Example 21 | US10544132, Example 24 | ...)
Affinity DataIC50:  7.80nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427129((3R)-2-[(4-chloro-2-methanesulfonylphenyl)methyl]-...)
Affinity DataIC50:  9.5nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427055((3R)-3-(4-chlorophenyl)-2-[(4-chlorophenyl)methyl]...)
Affinity DataIC50:  11nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427067(US10544132, Example 20 | US11236047, Example 20 | ...)
Affinity DataIC50:  11nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427159((3S)-3-(4-chlorophenyl)-3-[(1R)-1-(4-chlorophenyl)...)
Affinity DataIC50:  12nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM427148((3S)-3-(4-chlorophenyl)-3-[(1R)-1-(4-chlorophenyl)...)
Affinity DataIC50:  12nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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