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Found 8 Enz. Inhib. hit(s) with all data for entry = 8921
TargetKinase suppressor of Ras 2(Human)
Icahn School Of Medicine At Mount Sinai

US Patent
LigandPNGBDBM429286(APS-2-79 | US10548897, Compound 21)
Affinity DataIC50:  120nMAssay Description:The ATP-biotin assay was performed in buffer containing 25 mM Tris pH 7.5, 150 mM NaCl, 10 mM MgCl2, and 2% DMSO. Purified hKSR2-rMEK1 was assayed at...More data for this Ligand-Target Pair
TargetKinase suppressor of Ras 2(Human)
Icahn School Of Medicine At Mount Sinai

US Patent
LigandPNGBDBM50095227((6,7-Dimethoxy-quinazolin-4-yl)-(4-phenoxy-phenyl)...)
Affinity DataIC50:  602nMAssay Description:The ATP-biotin assay was performed in buffer containing 25 mM Tris pH 7.5, 150 mM NaCl, 10 mM MgCl2, and 2% DMSO. Purified hKSR2-rMEK1 was assayed at...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKinase suppressor of Ras 2(Human)
Icahn School Of Medicine At Mount Sinai

US Patent
LigandPNGBDBM429418(APS-2-12 | US10548897, Compound 10)
Affinity DataIC50:  1.50E+3nMAssay Description:The ATP-biotin assay was performed in buffer containing 25 mM Tris pH 7.5, 150 mM NaCl, 10 mM MgCl2, and 2% DMSO. Purified hKSR2-rMEK1 was assayed at...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKinase suppressor of Ras 2(Human)
Icahn School Of Medicine At Mount Sinai

US Patent
LigandPNGBDBM429420(APS-2-16 | D3RKN_87 | US10548897, Compound 11)
Affinity DataIC50:  2.50E+3nMAssay Description:The ATP-biotin assay was performed in buffer containing 25 mM Tris pH 7.5, 150 mM NaCl, 10 mM MgCl2, and 2% DMSO. Purified hKSR2-rMEK1 was assayed at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinase suppressor of Ras 2(Human)
Icahn School Of Medicine At Mount Sinai

US Patent
LigandPNGBDBM50291090((6,7-Dimethoxy-quinazolin-4-yl)-p-tolyl-amine; hyd...)
Affinity DataIC50: >1.00E+4nMAssay Description:The ATP-biotin assay was performed in buffer containing 25 mM Tris pH 7.5, 150 mM NaCl, 10 mM MgCl2, and 2% DMSO. Purified hKSR2-rMEK1 was assayed at...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKinase suppressor of Ras 2(Human)
Icahn School Of Medicine At Mount Sinai

US Patent
LigandPNGBDBM429421(APS-3-6 | US10548897, Compound 32)
Affinity DataIC50: >1.00E+4nMAssay Description:The ATP-biotin assay was performed in buffer containing 25 mM Tris pH 7.5, 150 mM NaCl, 10 mM MgCl2, and 2% DMSO. Purified hKSR2-rMEK1 was assayed at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinase suppressor of Ras 2(Human)
Icahn School Of Medicine At Mount Sinai

US Patent
LigandPNGBDBM429415(APS-3-77 | US10548897, Compound 50)
Affinity DataIC50: >1.00E+4nMAssay Description:The ATP-biotin assay was performed in buffer containing 25 mM Tris pH 7.5, 150 mM NaCl, 10 mM MgCl2, and 2% DMSO. Purified hKSR2-rMEK1 was assayed at...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinase suppressor of Ras 2(Human)
Icahn School Of Medicine At Mount Sinai

US Patent
LigandPNGBDBM50227519(4-(6,7-dimethoxyquinazolin-4-ylamino)phenol | CHEM...)
Affinity DataIC50: >1.00E+4nMAssay Description:The ATP-biotin assay was performed in buffer containing 25 mM Tris pH 7.5, 150 mM NaCl, 10 mM MgCl2, and 2% DMSO. Purified hKSR2-rMEK1 was assayed at...More data for this Ligand-Target Pair
In DepthDetails US Patent