Compile Data Set for Download or QSAR
maximum 50k data
Found 46 Enz. Inhib. hit(s) with all data for entry = 9107
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM442057(24(1-acetylpiperidin-4-yl)amino)-N-(4-(3,4-dihydro...)
Affinity DataIC50:  186nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM442031(US10647708, Compound 20)
Affinity DataIC50:  214nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM442030(US10647708, Compound 19)
Affinity DataIC50:  319nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM441959(4-Chloro-N-(4-(3,4-dihydroisoquinolin-2(1H)-yl)-3-...)
Affinity DataIC50:  359nMAssay Description:The κ uL assay reactions are run in Greiner brand black 384-well low volume plates. All reactions contained assay buffer (phosphate buffered sa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM442032(US10647708, Compound 21)
Affinity DataIC50:  415nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM442051(US10647708, Compound 40)
Affinity DataIC50:  769nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM442024(US10647708, Compound 14)
Affinity DataIC50:  910nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM442012(US10647708, Compound 3)
Affinity DataIC50:  925nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM442011(US10647708, Compound 2)
Affinity DataIC50:  1.13E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM442048(US10647708, Compound 37)
Affinity DataIC50:  1.19E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM442047(US10647708, Compound 36)
Affinity DataIC50:  1.20E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM442046(US10647708, Compound 35)
Affinity DataIC50:  1.21E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM442050(US10647708, Compound 39)
Affinity DataIC50:  1.22E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM442014(US10647708, Compound 5)
Affinity DataIC50:  1.33E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM442022(US10647708, Compound 12)
Affinity DataIC50:  1.60E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM442034(US10647708, Compound 23)
Affinity DataIC50:  1.69E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM442017(US10647708, Compound 7)
Affinity DataIC50:  1.94E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM442053(US10647708, Compound 42)
Affinity DataIC50:  2.83E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM442049(US10647708, Compound 38)
Affinity DataIC50:  2.88E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM442018(US10647708, Compound 8)
Affinity DataIC50:  3.09E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM442041(US10647708, Compound 30)
Affinity DataIC50:  3.12E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM442042(US10647708, Compound 31)
Affinity DataIC50:  3.16E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM442043(US10647708, Compound 32)
Affinity DataIC50:  3.54E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM442037(US10647708, Compound 26)
Affinity DataIC50:  3.75E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM442026(US10647708, Compound 15)
Affinity DataIC50:  3.98E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM442020(US10647708, Compound 10)
Affinity DataIC50:  3.98E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM442019(US10647708, Compound 9)
Affinity DataIC50:  4.35E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM442056(N-(4-(3,4-dihydroisoquinolin-2(1H)-yl)-3-hydroxybu...)
Affinity DataIC50:  5.23E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM442052(US10647708, Compound 41)
Affinity DataIC50:  5.29E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM442038(US10647708, Compound 27)
Affinity DataIC50:  5.62E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM442036(US10647708, Compound 25)
Affinity DataIC50:  6.35E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM442033(US10647708, Compound 22)
Affinity DataIC50:  7.02E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM442023(US10647708, Compound 13)
Affinity DataIC50:  7.09E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM442044(US10647708, Compound 33)
Affinity DataIC50:  7.45E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM442029(US10647708, Compound 18)
Affinity DataIC50:  9.79E+3nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM442040(US10647708, Compound 29)
Affinity DataIC50:  1.08E+4nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM442039(US10647708, Compound 28)
Affinity DataIC50:  1.23E+4nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM442027(US10647708, Compound 16)
Affinity DataIC50:  1.30E+4nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM442015(US10647708, Compound 6)
Affinity DataIC50:  1.31E+4nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM442055(2-Chloro-N-(4-(3,4-dihydroisoquinolin-2(1H)-yl)-3-...)
Affinity DataIC50:  1.37E+4nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM442028(US10647708, Compound 17)
Affinity DataIC50:  1.50E+4nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM442035(US10647708, Compound 24)
Affinity DataIC50:  2.54E+4nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM442021(US10647708, Compound 11)
Affinity DataIC50:  3.92E+4nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM442013(US10647708, Compound 4)
Affinity DataIC50:  5.17E+4nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM442045(US10647708, Compound 34)
Affinity DataIC50:  5.61E+4nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM442054(US10647708, Compound 43)
Affinity DataIC50:  1.06E+5nMAssay Description:Full-length PRMT5 enzyme (NCBI Reference sequence NP_006100.2) was co-expressed with Hiss-MEP50 in insect cells and purified via Nickel immobilized m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent