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Found 204 Enz. Inhib. hit(s) with all data for entry = 9133
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444416(US10662159, Example 1)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444474(US10662159, Example 67 | US10662159, Example 68)
Affinity DataIC50:  55nMAssay Description:Rat/homo FAAH:Procedure was followed as described for hMGL, except that arachidonoyl-methyl coumarin (was used as fluorigenic substrate. Compounds we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444423(US10662159, Example 8)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444424(US10662159, Example 9)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444431(US10662159, Example 16)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444432(US10662159, Example 17)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444434(US10662159, Example 19)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444436(US10662159, Example 21)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444437(US10662159, Example 22)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444438(US10662159, Example 23)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444440(US10662159, Example 25)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444441(US10662159, Example 26)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444445(US10662159, Example 30)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444446(US10662159, Example 31)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444447(US10662159, Example 32)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444448(US10662159, Example 35)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444451(US10662159, Example 39)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444452(US10662159, Example 40)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444453(US10662159, Example 41)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444454(US10662159, Example 42)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444455(US10662159, Example 43)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444457(US10662159, Example 45)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444457(US10662159, Example 45)
Affinity DataIC50:  55nMAssay Description:MGL: Compound inhibition of hMGL activity was assessed by a fluorometric assay recently developed in our laboratory (Makriyannis et al WO Patent Appl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444458(US10662159, Example 46)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444458(US10662159, Example 46)
Affinity DataIC50:  55nMAssay Description:MGL: Compound inhibition of hMGL activity was assessed by a fluorometric assay recently developed in our laboratory (Makriyannis et al WO Patent Appl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444459(US10662159, Example 47)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444460(US10662159, Example 48)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444460(US10662159, Example 48)
Affinity DataIC50:  55nMAssay Description:MGL: Compound inhibition of hMGL activity was assessed by a fluorometric assay recently developed in our laboratory (Makriyannis et al WO Patent Appl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444461(US10662159, Example 49)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444461(US10662159, Example 49)
Affinity DataIC50:  55nMAssay Description:MGL: Compound inhibition of hMGL activity was assessed by a fluorometric assay recently developed in our laboratory (Makriyannis et al WO Patent Appl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444462(US10662159, Example 50)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444462(US10662159, Example 50)
Affinity DataIC50:  55nMAssay Description:MGL: Compound inhibition of hMGL activity was assessed by a fluorometric assay recently developed in our laboratory (Makriyannis et al WO Patent Appl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444463(US10662159, Example 52)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444463(US10662159, Example 52)
Affinity DataIC50:  55nMAssay Description:MGL: Compound inhibition of hMGL activity was assessed by a fluorometric assay recently developed in our laboratory (Makriyannis et al WO Patent Appl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444464(US10662159, Example 53)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444464(US10662159, Example 53)
Affinity DataIC50:  55nMAssay Description:MGL: Compound inhibition of hMGL activity was assessed by a fluorometric assay recently developed in our laboratory (Makriyannis et al WO Patent Appl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444465(US10662159, Example 54)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444466(US10662159, Example 55)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444467(US10662159, Example 56)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444476(US10662159, Example 57)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444468(US10662159, Example 58)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444469(US10662159, Example 59)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444469(US10662159, Example 59)
Affinity DataIC50:  55nMAssay Description:MGL: Compound inhibition of hMGL activity was assessed by a fluorometric assay recently developed in our laboratory (Makriyannis et al WO Patent Appl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444469(US10662159, Example 59)
Affinity DataIC50:  55nMAssay Description:Rat/homo FAAH:Procedure was followed as described for hMGL, except that arachidonoyl-methyl coumarin (was used as fluorigenic substrate. Compounds we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444470(US10662159, Example 60)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444471(US10662159, Example 61)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444472(US10662159, Example 63)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444473(US10662159, Example 64)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444474(US10662159, Example 67 | US10662159, Example 68)
Affinity DataIC50:  55nMAssay Description:ABHD6: Certain compounds were tested for their ABHD6 and dual ABHD6/MGL inhibitory activity, which is expressed as % of inhibition or IC50 values. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Makscientific

US Patent
LigandPNGBDBM444474(US10662159, Example 67 | US10662159, Example 68)
Affinity DataIC50:  55nMAssay Description:MGL: Compound inhibition of hMGL activity was assessed by a fluorometric assay recently developed in our laboratory (Makriyannis et al WO Patent Appl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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