Compile Data Set for Download or QSAR
maximum 50k data
Found 33 Enz. Inhib. hit(s) with all data for entry = 9235
TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM451155(US10676499, Example 49)
Affinity DataKi:  20nMAssay Description:Dual histidine and Avi tagged human EIF4E (His6-3C-avi-eIF4E) was expressed in 8 L of TB Media. Induction by 0.4 mM IPTG occurred at 2.0 OD600, and c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM451148(US10676499, Example 29)
Affinity DataKi:  30nMAssay Description:Dual histidine and Avi tagged human EIF4E (His6-3C-avi-eIF4E) was expressed in 8 L of TB Media. Induction by 0.4 mM IPTG occurred at 2.0 OD600, and c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM451145(US10676499, Example 17)
Affinity DataKi:  30nMAssay Description:Dual histidine and Avi tagged human EIF4E (His6-3C-avi-eIF4E) was expressed in 8 L of TB Media. Induction by 0.4 mM IPTG occurred at 2.0 OD600, and c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM451159(US10676499, Example 57)
Affinity DataKi:  30nMAssay Description:Dual histidine and Avi tagged human EIF4E (His6-3C-avi-eIF4E) was expressed in 8 L of TB Media. Induction by 0.4 mM IPTG occurred at 2.0 OD600, and c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM451158(US10676499, Example 55)
Affinity DataKi:  40nMAssay Description:Dual histidine and Avi tagged human EIF4E (His6-3C-avi-eIF4E) was expressed in 8 L of TB Media. Induction by 0.4 mM IPTG occurred at 2.0 OD600, and c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM451147(US10676499, Example 26)
Affinity DataKi:  50nMAssay Description:Dual histidine and Avi tagged human EIF4E (His6-3C-avi-eIF4E) was expressed in 8 L of TB Media. Induction by 0.4 mM IPTG occurred at 2.0 OD600, and c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM451144(US10676499, Example 1)
Affinity DataKi:  100nMAssay Description:Dual histidine and Avi tagged human EIF4E (His6-3C-avi-eIF4E) was expressed in 8 L of TB Media. Induction by 0.4 mM IPTG occurred at 2.0 OD600, and c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM451150(US10676499, Example 33)
Affinity DataKi:  170nMAssay Description:Dual histidine and Avi tagged human EIF4E (His6-3C-avi-eIF4E) was expressed in 8 L of TB Media. Induction by 0.4 mM IPTG occurred at 2.0 OD600, and c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM451146(US10676499, Example 18)
Affinity DataKi:  180nMAssay Description:Dual histidine and Avi tagged human EIF4E (His6-3C-avi-eIF4E) was expressed in 8 L of TB Media. Induction by 0.4 mM IPTG occurred at 2.0 OD600, and c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM451156(US10676499, Example 53)
Affinity DataKi:  190nMAssay Description:Dual histidine and Avi tagged human EIF4E (His6-3C-avi-eIF4E) was expressed in 8 L of TB Media. Induction by 0.4 mM IPTG occurred at 2.0 OD600, and c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM451160(US10676499, Example 58)
Affinity DataKi:  1.00E+3nMAssay Description:Dual histidine and Avi tagged human EIF4E (His6-3C-avi-eIF4E) was expressed in 8 L of TB Media. Induction by 0.4 mM IPTG occurred at 2.0 OD600, and c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM451151(US10676499, Example 40)
Affinity DataKi:  2.36E+3nMAssay Description:Dual histidine and Avi tagged human EIF4E (His6-3C-avi-eIF4E) was expressed in 8 L of TB Media. Induction by 0.4 mM IPTG occurred at 2.0 OD600, and c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM451157(US10676499, Example 54)
Affinity DataKi:  2.78E+3nMAssay Description:Dual histidine and Avi tagged human EIF4E (His6-3C-avi-eIF4E) was expressed in 8 L of TB Media. Induction by 0.4 mM IPTG occurred at 2.0 OD600, and c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM451154(US10676499, Example 43)
Affinity DataKi:  3.17E+3nMAssay Description:Dual histidine and Avi tagged human EIF4E (His6-3C-avi-eIF4E) was expressed in 8 L of TB Media. Induction by 0.4 mM IPTG occurred at 2.0 OD600, and c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM451153(US10676499, Example 42)
Affinity DataKi:  4.90E+3nMAssay Description:Dual histidine and Avi tagged human EIF4E (His6-3C-avi-eIF4E) was expressed in 8 L of TB Media. Induction by 0.4 mM IPTG occurred at 2.0 OD600, and c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM451152(US10676499, Example 41)
Affinity DataKi:  8.82E+3nMAssay Description:Dual histidine and Avi tagged human EIF4E (His6-3C-avi-eIF4E) was expressed in 8 L of TB Media. Induction by 0.4 mM IPTG occurred at 2.0 OD600, and c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM451149(US10676499, Example 32)
Affinity DataKi:  9.36E+4nMAssay Description:Dual histidine and Avi tagged human EIF4E (His6-3C-avi-eIF4E) was expressed in 8 L of TB Media. Induction by 0.4 mM IPTG occurred at 2.0 OD600, and c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM451159(US10676499, Example 57)
Affinity DataKd:  6.50E+3nMAssay Description:A subset of compounds was further characterized to determine dissociation constants using thermodynamic (Steady State Affinity) binding analysis.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM451158(US10676499, Example 55)
Affinity DataKd:  110nMAssay Description:A subset of compounds was further characterized to determine dissociation constants using thermodynamic (Steady State Affinity) binding analysis.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM451157(US10676499, Example 54)
Affinity DataKd:  6.00E+3nMAssay Description:A subset of compounds was further characterized to determine dissociation constants using thermodynamic (Steady State Affinity) binding analysis.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM451156(US10676499, Example 53)
Affinity DataKd:  6.00E+3nMAssay Description:A subset of compounds was further characterized to determine dissociation constants using thermodynamic (Steady State Affinity) binding analysis.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM451155(US10676499, Example 49)
Affinity DataKd:  6.50E+3nMAssay Description:A subset of compounds was further characterized to determine dissociation constants using thermodynamic (Steady State Affinity) binding analysis.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM451154(US10676499, Example 43)
Affinity DataKd:  580nMAssay Description:A subset of compounds was further characterized to determine dissociation constants using thermodynamic (Steady State Affinity) binding analysis.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM451153(US10676499, Example 42)
Affinity DataKd:  6.50E+3nMAssay Description:A subset of compounds was further characterized to determine dissociation constants using thermodynamic (Steady State Affinity) binding analysis.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM451152(US10676499, Example 41)
Affinity DataKd:  20nMAssay Description:A subset of compounds was further characterized to determine dissociation constants using thermodynamic (Steady State Affinity) binding analysis.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM451151(US10676499, Example 40)
Affinity DataKd:  6.50E+3nMAssay Description:A subset of compounds was further characterized to determine dissociation constants using thermodynamic (Steady State Affinity) binding analysis.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM451150(US10676499, Example 33)
Affinity DataKd:  220nMAssay Description:A subset of compounds was further characterized to determine dissociation constants using thermodynamic (Steady State Affinity) binding analysis.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM451149(US10676499, Example 32)
Affinity DataKd:  30nMAssay Description:A subset of compounds was further characterized to determine dissociation constants using thermodynamic (Steady State Affinity) binding analysis.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM451148(US10676499, Example 29)
Affinity DataKd:  6.50E+3nMAssay Description:A subset of compounds was further characterized to determine dissociation constants using thermodynamic (Steady State Affinity) binding analysis.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM451147(US10676499, Example 26)
Affinity DataKd:  6.50E+3nMAssay Description:A subset of compounds was further characterized to determine dissociation constants using thermodynamic (Steady State Affinity) binding analysis.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM451146(US10676499, Example 18)
Affinity DataKd:  160nMAssay Description:A subset of compounds was further characterized to determine dissociation constants using thermodynamic (Steady State Affinity) binding analysis.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM451160(US10676499, Example 58)
Affinity DataKd:  410nMAssay Description:A subset of compounds was further characterized to determine dissociation constants using thermodynamic (Steady State Affinity) binding analysis.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM451144(US10676499, Example 1)
Affinity DataKd:  300nMAssay Description:A subset of compounds was further characterized to determine dissociation constants using thermodynamic (Steady State Affinity) binding analysis.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent