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Found 17 Enz. Inhib. hit(s) with all data for entry = 9256
TargetD(1A) dopamine receptor(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM50373192(CHEMBL405519 | US10729710, Compound (I))
Affinity DataEC50:  3.30nMAssay Description:Dopamine D1 receptor agonism was measured using a HTRF cAMP from CisBio using the protocol developed by HD Biosciences (China). Briefly, the assay is...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM453280(US10729710, Compound (Id-ib))
Affinity DataEC50: >3.00E+4nMAssay Description:Dopamine D2 receptor agonism was measured using a calcium mobilization assay protocol developed by HD Biosciences (China). Briefly, HEK293/G15 cells ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2B(Mus musculus (Mouse))
H. Lundbeck

US Patent
LigandPNGBDBM50373192(CHEMBL405519 | US10729710, Compound (I))
Affinity DataEC50:  2.90E+3nMAssay Description:Evaluation of the agonist activity of compounds (I), (Ia) and (Ib) at the human 5-HT2B receptor was performed by Eurofins/Cerep (France) measuring th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(1A) dopamine receptor(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM453276(US10729710, Compound (Ia))
Affinity DataEC50: >1.00E+3nMAssay Description:Dopamine D1 receptor agonism was measured using a HTRF cAMP from CisBio using the protocol developed by HD Biosciences (China). Briefly, the assay is...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM453276(US10729710, Compound (Ia))
Affinity DataEC50: >1.00E+3nMAssay Description:Dopamine D2 receptor agonism was measured using a calcium mobilization assay protocol developed by HD Biosciences (China). Briefly, HEK293/G15 cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2B(Mus musculus (Mouse))
H. Lundbeck

US Patent
LigandPNGBDBM453276(US10729710, Compound (Ia))
Affinity DataEC50: >6.00E+3nMAssay Description:Evaluation of the agonist activity of compounds (I), (Ia) and (Ib) at the human 5-HT2B receptor was performed by Eurofins/Cerep (France) measuring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(1A) dopamine receptor(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM453277(US10729710, Compound (Ib))
Affinity DataEC50: >1.00E+3nMAssay Description:Dopamine D1 receptor agonism was measured using a HTRF cAMP from CisBio using the protocol developed by HD Biosciences (China). Briefly, the assay is...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM453277(US10729710, Compound (Ib))
Affinity DataEC50:  46nMAssay Description:Dopamine D2 receptor agonism was measured using a calcium mobilization assay protocol developed by HD Biosciences (China). Briefly, HEK293/G15 cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2B(Mus musculus (Mouse))
H. Lundbeck

US Patent
LigandPNGBDBM453277(US10729710, Compound (Ib))
Affinity DataEC50:  3.80nMAssay Description:Evaluation of the agonist activity of compounds (I), (Ia) and (Ib) at the human 5-HT2B receptor was performed by Eurofins/Cerep (France) measuring th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(1A) dopamine receptor(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM453278(US10729710, Compound (Id-ia))
Affinity DataEC50:  2.70E+3nMAssay Description:Dopamine D1 receptor agonism was measured using a HTRF cAMP from CisBio using the protocol developed by HD Biosciences (China). Briefly, the assay is...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM453278(US10729710, Compound (Id-ia))
Affinity DataEC50:  1.10E+3nMAssay Description:Dopamine D2 receptor agonism was measured using a calcium mobilization assay protocol developed by HD Biosciences (China). Briefly, HEK293/G15 cells ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetD(1A) dopamine receptor(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM453280(US10729710, Compound (Id-ib))
Affinity DataEC50:  1.80E+3nMAssay Description:Dopamine D1 receptor agonism was measured using a HTRF cAMP from CisBio using the protocol developed by HD Biosciences (China). Briefly, the assay is...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM453280(US10729710, Compound (Id-ib))
Affinity DataEC50:  1.30E+3nMAssay Description:Dopamine D2 receptor agonism was measured using a calcium mobilization assay protocol developed by HD Biosciences (China). Briefly, HEK293/G15 cells ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetD(1A) dopamine receptor(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM453286(US10729710, Compound (Id-iia))
Affinity DataEC50: >3.00E+4nMAssay Description:Dopamine D1 receptor agonism was measured using a HTRF cAMP from CisBio using the protocol developed by HD Biosciences (China). Briefly, the assay is...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM453286(US10729710, Compound (Id-iia))
Affinity DataEC50: >3.00E+4nMAssay Description:Dopamine D2 receptor agonism was measured using a calcium mobilization assay protocol developed by HD Biosciences (China). Briefly, HEK293/G15 cells ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetD(1A) dopamine receptor(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM453280(US10729710, Compound (Id-ib))
Affinity DataEC50: >3.00E+4nMAssay Description:Dopamine D1 receptor agonism was measured using a HTRF cAMP from CisBio using the protocol developed by HD Biosciences (China). Briefly, the assay is...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM50373192(CHEMBL405519 | US10729710, Compound (I))
Affinity DataEC50:  1.30nMAssay Description:Dopamine D2 receptor agonism was measured using a calcium mobilization assay protocol developed by HD Biosciences (China). Briefly, HEK293/G15 cells ...More data for this Ligand-Target Pair
In DepthDetails US Patent