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Found 13 Enz. Inhib. hit(s) with all data for entry = 9598
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
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US Patent
LigandPNGBDBM246868(US10053465, 7 | US10065963, Compound 7 | US1012515...)
Affinity DataIC50:  0.300nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
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US Patent
LigandPNGBDBM50250929(CHEMBL4066193 | US10875847, Compound 1)
Affinity DataIC50:  0.430nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
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US Patent
LigandPNGBDBM50021656(BARICITINIB | INCB-028050 | LY-3009104 | US1011290...)
Affinity DataIC50:  0.470nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
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US Patent
LigandPNGBDBM294916(US10112907, Example 00027 | US10206907, Compound 1...)
Affinity DataIC50:  0.630nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
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US Patent
LigandPNGBDBM50355501(INCB-018424 | RUXOLITINIB | RUXOLITINIB PHOSPHATE ...)
Affinity DataIC50:  1nMMore data for this Ligand-Target Pair
In DepthDetails US PatentDrugBank

TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
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US Patent
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)
Affinity DataIC50:  1.35nMMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
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US Patent
LigandPNGBDBM147798(US10875847, Reference Compound A | US8962608, 28-1...)
Affinity DataIC50:  1.67nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
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US Patent
LigandPNGBDBM185700(US10875847, Compound Oclacitinib | US9161939, 1a |...)
Affinity DataIC50:  3.40nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
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US Patent
LigandPNGBDBM50250929(CHEMBL4066193 | US10875847, Compound 1)
Affinity DataIC50:  5.89nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
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US Patent
LigandPNGBDBM476345(US10875847, Compound Enantiomer of 1)
Affinity DataIC50:  17.7nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
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US Patent
LigandPNGBDBM476345(US10875847, Compound Enantiomer of 1)
Affinity DataIC50:  216nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
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US Patent
LigandPNGBDBM50250929(CHEMBL4066193 | US10875847, Compound 1)
Affinity DataIC50:  1.13E+3nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Intervet

US Patent
LigandPNGBDBM476345(US10875847, Compound Enantiomer of 1)
Affinity DataIC50: >1.25E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent