Compile Data Set for Download or QSAR
maximum 50k data
Found 66 Enz. Inhib. hit(s) with all data for entry = 9863
TargetKappa-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM494092(US10988481, Compound 9)
Affinity DataKi:  0.149nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM494110(US10988481, Compound 11)
Affinity DataKi:  0.160nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM494139(US10988481, Compound 14)
Affinity DataKi:  0.166nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM494197(US10988481, Compound 17)
Affinity DataKi:  0.167nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM494208(US10988481, Compound 18)
Affinity DataKi:  0.175nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM494104(US10988481, Compound 10)
Affinity DataKi:  0.178nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM494161(US10988481, Compound 15)
Affinity DataKi:  0.188nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM494110(US10988481, Compound 11)
Affinity DataKi:  0.192nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM494208(US10988481, Compound 18)
Affinity DataKi:  0.203nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM494073(US10988481, Compound 6)
Affinity DataKi:  0.229nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM494127(US10988481, Compound 12)
Affinity DataKi:  0.235nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM494166(US10988481, Compound 16)
Affinity DataKi:  0.241nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM494139(US10988481, Compound 14)
Affinity DataKi:  0.25nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM494137(US10988481, Compound 13)
Affinity DataKi:  0.259nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM494003(US10988481, Compound 3)
Affinity DataKi:  0.264nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM494104(US10988481, Compound 10)
Affinity DataKi:  0.287nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM493969(US10988481, Compound 2)
Affinity DataKi:  0.288nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM494092(US10988481, Compound 9)
Affinity DataKi:  0.293nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM60212((4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(o...)
Affinity DataKi:  0.330nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
In DepthDetails US PatentDrugBank

TargetMu-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM60212((4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(o...)
Affinity DataKi:  0.330nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
In DepthDetails US PatentDrugBank

TargetMu-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM493968(US10988481, Compound 1)
Affinity DataKi:  0.363nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM494197(US10988481, Compound 17)
Affinity DataKi:  0.387nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM494043(US10988481, Compound 5)
Affinity DataKi:  0.434nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM494091(US10988481, Compound 8)
Affinity DataKi:  0.437nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM494137(US10988481, Compound 13)
Affinity DataKi:  0.512nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM494161(US10988481, Compound 15)
Affinity DataKi:  0.520nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM494004(US10988481, Compound 4)
Affinity DataKi:  0.763nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM494088(US10988481, Compound 7)
Affinity DataKi:  0.837nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM493968(US10988481, Compound 1)
Affinity DataKi:  0.926nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM494166(US10988481, Compound 16)
Affinity DataKi:  0.947nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM493969(US10988481, Compound 2)
Affinity DataKi:  0.984nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM493967(US10988481, Compound NAQ)
Affinity DataKi:  1.11nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM493967(US10988481, Compound NAQ)
Affinity DataKi:  1.11nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM494091(US10988481, Compound 8)
Affinity DataKi:  1.36nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM60212((4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(o...)
Affinity DataKi:  1.44nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
In DepthDetails US PatentDrugBank

TargetKappa-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM60212((4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(o...)
Affinity DataKi:  1.44nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
In DepthDetails US PatentDrugBank

TargetKappa-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM494003(US10988481, Compound 3)
Affinity DataKi:  1.49nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDelta-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM494104(US10988481, Compound 10)
Affinity DataKi:  1.54nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM494043(US10988481, Compound 5)
Affinity DataKi:  1.63nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM494073(US10988481, Compound 6)
Affinity DataKi:  1.69nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM494127(US10988481, Compound 12)
Affinity DataKi:  1.94nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM494088(US10988481, Compound 7)
Affinity DataKi:  3.13nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM494004(US10988481, Compound 4)
Affinity DataKi:  3.45nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDelta-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM494139(US10988481, Compound 14)
Affinity DataKi:  6.23nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDelta-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM494092(US10988481, Compound 9)
Affinity DataKi:  6.73nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDelta-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM494110(US10988481, Compound 11)
Affinity DataKi:  7.17nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDelta-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM494088(US10988481, Compound 7)
Affinity DataKi:  9.17nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDelta-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM494003(US10988481, Compound 3)
Affinity DataKi:  9.26nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDelta-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM493969(US10988481, Compound 2)
Affinity DataKi:  10.5nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDelta-type opioid receptor(Homo sapiens (Human))
Virginia Commonwealth University

US Patent
LigandPNGBDBM494073(US10988481, Compound 6)
Affinity DataKi:  10.9nMAssay Description:The competition binding assay was conducted to determine the affinity and selectivity of the synthesized compounds to MOR over KOR and DOR. The Kd an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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