Affinity Data by Patent

Patent code US11007200

Found 16 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM497388 (US11007200, Example 4a) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	US Patent	15.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
MediSynergics, LLC US Patent									US Patent US11007200 (2021)
MediSynergics, LLC US Patent					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM497384 (US11007200, Example 2a) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	17.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
MediSynergics, LLC US Patent					Assay Description Procedures employed by the PDSP as described in the NIMH-PDSP Assay Protocol Book, Version II. The standard drug used in both Sigma subtype assays is...				US Patent US11007200 (2021)
MediSynergics, LLC US Patent					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM497386 (US11007200, Example 3a) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	US Patent	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
MediSynergics, LLC US Patent									US Patent US11007200 (2021)
MediSynergics, LLC US Patent					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM497386 (US11007200, Example 3a) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	35.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
MediSynergics, LLC US Patent					Assay Description Procedures employed by the PDSP as described in the NIMH-PDSP Assay Protocol Book, Version II. The standard drug used in both Sigma subtype assays is...				US Patent US11007200 (2021)
MediSynergics, LLC US Patent					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM497391 (US11007200, Example 2b) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	37.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
MediSynergics, LLC US Patent					Assay Description Procedures employed by the PDSP as described in the NIMH-PDSP Assay Protocol Book, Version II. The standard drug used in both Sigma subtype assays is...				US Patent US11007200 (2021)
MediSynergics, LLC US Patent					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM497384 (US11007200, Example 2a) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	US Patent	59.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
MediSynergics, LLC US Patent									US Patent US11007200 (2021)
MediSynergics, LLC US Patent					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM497390 (US11007200, Example 13a) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
MediSynergics, LLC US Patent					Assay Description Procedures employed by the PDSP as described in the NIMH-PDSP Assay Protocol Book, Version II. The standard drug used in both Sigma subtype assays is...				US Patent US11007200 (2021)
MediSynergics, LLC US Patent					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM497388 (US11007200, Example 4a) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	97.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
MediSynergics, LLC US Patent					Assay Description Procedures employed by the PDSP as described in the NIMH-PDSP Assay Protocol Book, Version II. The standard drug used in both Sigma subtype assays is...				US Patent US11007200 (2021)
MediSynergics, LLC US Patent					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM497390 (US11007200, Example 13a) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	US Patent	98	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
MediSynergics, LLC US Patent									US Patent US11007200 (2021)
MediSynergics, LLC US Patent					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM497392 (US11007200, Example 13b) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	146	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
MediSynergics, LLC US Patent					Assay Description Procedures employed by the PDSP as described in the NIMH-PDSP Assay Protocol Book, Version II. The standard drug used in both Sigma subtype assays is...				US Patent US11007200 (2021)
MediSynergics, LLC US Patent					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM497387 (US11007200, Example 3b) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	217	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
MediSynergics, LLC US Patent					Assay Description Procedures employed by the PDSP as described in the NIMH-PDSP Assay Protocol Book, Version II. The standard drug used in both Sigma subtype assays is...				US Patent US11007200 (2021)
MediSynergics, LLC US Patent					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM497391 (US11007200, Example 2b) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	US Patent	305	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
MediSynergics, LLC US Patent									US Patent US11007200 (2021)
MediSynergics, LLC US Patent					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM497389 (US11007200, Example 4b) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	US Patent	426	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
MediSynergics, LLC US Patent									US Patent US11007200 (2021)
MediSynergics, LLC US Patent					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM497392 (US11007200, Example 13b) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	US Patent	435	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
MediSynergics, LLC US Patent									US Patent US11007200 (2021)
MediSynergics, LLC US Patent					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM497387 (US11007200, Example 3b) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar	PC cid PC sid UniChem	US Patent	675	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
MediSynergics, LLC US Patent									US Patent US11007200 (2021)
MediSynergics, LLC US Patent					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM497389 (US11007200, Example 4b) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	697	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
MediSynergics, LLC US Patent					Assay Description Procedures employed by the PDSP as described in the NIMH-PDSP Assay Protocol Book, Version II. The standard drug used in both Sigma subtype assays is...				US Patent US11007200 (2021)
MediSynergics, LLC US Patent					More data for this Ligand-Target Pair

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* indicates data uncertainty>20%