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Patent code US11026923

Compile Data Set for Download or QSAR

Found 606 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B


(Homo sapiens (Human))
BDBM501501
PNG
(5-(2-ethoxy-3-pyridyl)-3-methyl-1-[1- methylpropyl...)
Show SMILES CCOc1ncccc1-c1cc(NCc2cc(C)[nH]n2)c(NC(C)CC)c(n1)C(C)=N
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n/an/a 0.0420n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...


US Patent US11026923 (2021)

More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B


(Homo sapiens (Human))
BDBM501502
PNG
(5-(2-ethoxy-3-pyridyl)-3-methyl-N-[1- methylimidaz...)
Show SMILES CCOc1ncccc1-c1cc(NCc2cn(C)cn2)c(NC(C)CC)c(n1)C(C)=N
Show InChI InChI=1S/C23H31N7O/c1-6-15(3)28-22-20(26-12-17-13-30(5)14-27-17)11-19(29-21(22)16(4)24)18-9-8-10-25-23(18)31-7-2/h8-11,13-15,24,28H,6-7,12H2,1-5H3,(H,26,29)
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n/an/a 0.0450n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...


US Patent US11026923 (2021)

More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B


(Homo sapiens (Human))
BDBM279063
PNG
(1-isopropyl-3-methyl-N-[(1-methylpyrazol-4-yl)meth...)
Show SMILES CCCOc1ncccc1-c1cc(NCc2cnn(C)c2)c2n(nc(C)c2n1)C(C)C
Show InChI InChI=1S/C23H29N7O/c1-6-10-31-23-18(8-7-9-24-23)19-11-20(25-12-17-13-26-29(5)14-17)22-21(27-19)16(4)28-30(22)15(2)3/h7-9,11,13-15H,6,10,12H2,1-5H3,(H,25,27)
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n/an/a 0.0650n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...


US Patent US11026923 (2021)

More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B


(Homo sapiens (Human))
BDBM279017
PNG
(5-(2-ethoxypyridin-3-yl)-1-isopropyl-3-methyl-N-((...)
Show SMILES CCOc1ncccc1-c1cc(NCc2cc(C)[nH]n2)c2n(nc(C)c2n1)C(C)C
Show InChI InChI=1S/C22H27N7O/c1-6-30-22-17(8-7-9-23-22)18-11-19(24-12-16-10-14(4)26-27-16)21-20(25-18)15(5)28-29(21)13(2)3/h7-11,13H,6,12H2,1-5H3,(H,24,25)(H,26,27)
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n/an/a 0.0690n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...


US Patent US11026923 (2021)

More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B


(Homo sapiens (Human))
BDBM278972
PNG
(5-(2-ethoxy-3-pyridyl)-1-isopropyl-3-methyl-N-[(5-...)
Show SMILES CCOc1ncccc1-c1cc(NCc2ncc(C)s2)c2n(nc(C)c2n1)C(C)C
Show InChI InChI=1S/C22H26N6OS/c1-6-29-22-16(8-7-9-23-22)17-10-18(24-12-19-25-11-14(4)30-19)21-20(26-17)15(5)27-28(21)13(2)3/h7-11,13H,6,12H2,1-5H3,(H,24,26)
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n/an/a 0.0710n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...


US Patent US11026923 (2021)

More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B


(Homo sapiens (Human))
BDBM501505
PNG
(3-methyl-1-[1-methylpropyl]-5-(2-propoxy-3- pyridy...)
Show SMILES CCCOc1ncccc1-c1cc(NCc2cc[nH]n2)c(NC(C)CC)c(n1)C(C)=N
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H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...


US Patent US11026923 (2021)

More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B


(Homo sapiens (Human))
BDBM279114
PNG
(1-isopropyl-3-methyl-N-[(1-methyl-1,2,4-triazol-3-...)
Show SMILES CCCOc1ncccc1-c1cc(NCc2ncn(C)n2)c2n(nc(C)c2n1)C(C)C
Show InChI InChI=1S/C22H28N8O/c1-6-10-31-22-16(8-7-9-23-22)17-11-18(24-12-19-25-13-29(5)28-19)21-20(26-17)15(4)27-30(21)14(2)3/h7-9,11,13-14H,6,10,12H2,1-5H3,(H,24,26)
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n/an/a 0.0950n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...


US Patent US11026923 (2021)

More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B


(Homo sapiens (Human))
BDBM501512
PNG
(1-isopropyl-3-methyl-N-[(1-methylimidazol-4- yl)me...)
Show SMILES CCCOc1ncccc1-c1cc(NCc2cn(C)cn2)c2n(nc(C)c2n1)C(C)CC
Show InChI InChI=1S/C24H31N7O/c1-6-11-32-24-19(9-8-10-25-24)20-12-21(26-13-18-14-30(5)15-27-18)23-22(28-20)17(4)29-31(23)16(3)7-2/h8-10,12,14-16H,6-7,11,13H2,1-5H3,(H,26,28)
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H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...


US Patent US11026923 (2021)

More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B


(Homo sapiens (Human))
BDBM278973
PNG
(5-(2-ethoxy-3-pyridyl)-1-isopropyl-3-methyl-N-[(5-...)
Show SMILES CCOc1ncccc1-c1cc(NCc2cc(C)on2)c2n(nc(C)c2n1)C(C)C
Show InChI InChI=1S/C22H26N6O2/c1-6-29-22-17(8-7-9-23-22)18-11-19(24-12-16-10-14(4)30-27-16)21-20(25-18)15(5)26-28(21)13(2)3/h7-11,13H,6,12H2,1-5H3,(H,24,25)
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n/an/a 0.110n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...


US Patent US11026923 (2021)

More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B


(Homo sapiens (Human))
BDBM279001
PNG
(5-(2-ethoxy-3-pyridyl)-1-isopropyl-3-methyl-N-[(1-...)
Show SMILES CCOc1ncccc1-c1cc(NCc2ncn(C)n2)c2n(nc(C)c2n1)C(C)C
Show InChI InChI=1S/C21H26N8O/c1-6-30-21-15(8-7-9-22-21)16-10-17(23-11-18-24-12-28(5)27-18)20-19(25-16)14(4)26-29(20)13(2)3/h7-10,12-13H,6,11H2,1-5H3,(H,23,25)
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n/an/a 0.110n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...


US Patent US11026923 (2021)

More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B


(Homo sapiens (Human))
BDBM501504
PNG
(3-methyl-1-[1-methylpropyll-N-[(1-methyl- 1,2,4-tr...)
Show SMILES CCCOc1ncccc1-c1cc(NCc2ncn(C)n2)c(NC(C)CC)c(n1)C(C)=N
Show InChI InChI=1S/C23H32N8O/c1-6-11-32-23-17(9-8-10-25-23)18-12-19(26-13-20-27-14-31(5)30-20)22(28-15(3)7-2)21(29-18)16(4)24/h8-10,12,14-15,24,28H,6-7,11,13H2,1-5H3,(H,26,29)
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H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...


US Patent US11026923 (2021)

More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B


(Homo sapiens (Human))
BDBM279002
PNG
(5-(2-ethoxy-3-pyridyl)-1-isopropyl-3-methyl-N-[(2-...)
Show SMILES CCOc1ncccc1-c1cc(NCc2cnc(C)s2)c2n(nc(C)c2n1)C(C)C
Show InChI InChI=1S/C22H26N6OS/c1-6-29-22-17(8-7-9-23-22)18-10-19(25-12-16-11-24-15(5)30-16)21-20(26-18)14(4)27-28(21)13(2)3/h7-11,13H,6,12H2,1-5H3,(H,25,26)
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n/an/a 0.140n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...


US Patent US11026923 (2021)

More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B


(Homo sapiens (Human))
BDBM501437
PNG
(3-methyl-1-[1-methylpropyl]-N-[(2- methyltetrazol-...)
Show SMILES CCCOc1ncccc1C\C=C(\NCc1nnn(C)n1)c1cc(C)nn1C(C)CC
Show InChI InChI=1S/C22H32N8O/c1-6-13-31-22-18(9-8-12-23-22)10-11-19(24-15-21-25-28-29(5)27-21)20-14-16(3)26-30(20)17(4)7-2/h8-9,11-12,14,17,24H,6-7,10,13,15H2,1-5H3/b19-11+
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H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...


US Patent US11026923 (2021)

More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent 3',5'-cyclic phosphodiesterase 1A


(Homo sapiens (Human))
BDBM501502
PNG
(5-(2-ethoxy-3-pyridyl)-3-methyl-N-[1- methylimidaz...)
Show SMILES CCOc1ncccc1-c1cc(NCc2cn(C)cn2)c(NC(C)CC)c(n1)C(C)=N
Show InChI InChI=1S/C23H31N7O/c1-6-15(3)28-22-20(26-12-17-13-30(5)14-27-17)11-19(29-21(22)16(4)24)18-9-8-10-25-23(18)31-7-2/h8-11,13-15,24,28H,6-7,12H2,1-5H3,(H,26,29)
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H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...


US Patent US11026923 (2021)

More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B


(Homo sapiens (Human))
BDBM501491
PNG
(5-(2-ethoxy-3-pyridyl)-3-methyl-1-[1- methylpropyl...)
Show SMILES CCOc1ncccc1-c1cc(NCC(=N)\N=C/N)c(NC(C)CC)c(n1)C(C)=N
Show InChI InChI=1S/C21H30N8O/c1-5-13(3)28-20-17(26-11-18(24)27-12-22)10-16(29-19(20)14(4)23)15-8-7-9-25-21(15)30-6-2/h7-10,12-13,23,28H,5-6,11H2,1-4H3,(H,26,29)(H3,22,24,27)
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H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...


US Patent US11026923 (2021)

More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B


(Homo sapiens (Human))
BDBM279073
PNG
(5-(2-ethoxy-3-pyridyl)-1-isopropyl-N-[(2-methoxy-4...)
Show SMILES CCOc1ncccc1-c1cc(NCc2ccnc(OC)c2)c2n(nc(C)c2n1)C(C)C
Show InChI InChI=1S/C24H28N6O2/c1-6-32-24-18(8-7-10-26-24)19-13-20(27-14-17-9-11-25-21(12-17)31-5)23-22(28-19)16(4)29-30(23)15(2)3/h7-13,15H,6,14H2,1-5H3,(H,27,28)
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n/an/a 0.160n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...


US Patent US11026923 (2021)

More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B


(Homo sapiens (Human))
BDBM279135
PNG
(5-(2-ethoxy-3-pyridyl)-N-[[5-(fluoromethyl)isoxazo...)
Show SMILES CCOc1ncccc1-c1cc(NCc2cc(CF)on2)c2n(nc(C)c2n1)C(C)C
Show InChI InChI=1S/C22H25FN6O2/c1-5-30-22-17(7-6-8-24-22)18-10-19(25-12-15-9-16(11-23)31-28-15)21-20(26-18)14(4)27-29(21)13(2)3/h6-10,13H,5,11-12H2,1-4H3,(H,25,26)
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H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...


US Patent US11026923 (2021)

More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B


(Homo sapiens (Human))
BDBM279022
PNG
(5-(2-ethoxy-3-pyridyl)-1-isopropyl-3-methyl-N-[(5-...)
Show SMILES CCOc1ncccc1-c1cc(NCc2noc(C)n2)c2n(nc(C)c2n1)C(C)C
Show InChI InChI=1S/C21H25N7O2/c1-6-29-21-15(8-7-9-22-21)16-10-17(23-11-18-24-14(5)30-27-18)20-19(25-16)13(4)26-28(20)12(2)3/h7-10,12H,6,11H2,1-5H3,(H,23,25)
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n/an/a 0.170n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...


US Patent US11026923 (2021)

More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B


(Homo sapiens (Human))
BDBM279028
PNG
(5-(2-ethoxypyridin-3-yl)-1-isopropyl-3-methyl-N-((...)
Show SMILES CCOc1ncccc1-c1cc(NCc2cn(C)cn2)c2n(nc(C)c2n1)C(C)C
Show InChI InChI=1S/C22H27N7O/c1-6-30-22-17(8-7-9-23-22)18-10-19(24-11-16-12-28(5)13-25-16)21-20(26-18)15(4)27-29(21)14(2)3/h7-10,12-14H,6,11H2,1-5H3,(H,24,26)
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n/an/a 0.170n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...


US Patent US11026923 (2021)

More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B


(Homo sapiens (Human))
BDBM279024
PNG
(N-[(1,5-dimethylpyrazol-3-yl)methyl]-5-(2-ethoxy-3...)
Show SMILES CCOc1ncccc1-c1cc(NCc2cc(C)n(C)n2)c2n(nc(C)c2n1)C(C)C
Show InChI InChI=1S/C23H29N7O/c1-7-31-23-18(9-8-10-24-23)19-12-20(25-13-17-11-15(4)29(6)28-17)22-21(26-19)16(5)27-30(22)14(2)3/h8-12,14H,7,13H2,1-6H3,(H,25,26)
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n/an/a 0.180n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...


US Patent US11026923 (2021)

More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B


(Homo sapiens (Human))
BDBM278976
PNG
(5-(2-ethoxy-3-pyridyl)-1-isopropyl-3-methyl-N-[(1-...)
Show SMILES CCOc1ncccc1-c1cc(NCc2cn(C)nn2)c2n(nc(C)c2n1)C(C)C
Show InChI InChI=1S/C21H26N8O/c1-6-30-21-16(8-7-9-22-21)17-10-18(23-11-15-12-28(5)27-25-15)20-19(24-17)14(4)26-29(20)13(2)3/h7-10,12-13H,6,11H2,1-5H3,(H,23,24)
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n/an/a 0.220n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...


US Patent US11026923 (2021)

More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B


(Homo sapiens (Human))
BDBM279054
PNG
(5-(2-ethoxy-3-pyridyl)-N-[(2-fluoro-3-pyridyl)meth...)
Show SMILES CCOc1ncccc1-c1cc(NCc2cccnc2F)c2n(nc(C)c2n1)C(C)C
Show InChI InChI=1S/C23H25FN6O/c1-5-31-23-17(9-7-11-26-23)18-12-19(27-13-16-8-6-10-25-22(16)24)21-20(28-18)15(4)29-30(21)14(2)3/h6-12,14H,5,13H2,1-4H3,(H,27,28)
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n/an/a 0.220n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...


US Patent US11026923 (2021)

More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B


(Homo sapiens (Human))
BDBM279047
PNG
(5-(2-ethoxy-3-pyridyl)-1-isopropyl-3-methyl-N-[[2-...)
Show SMILES CCOc1ncccc1-c1cc(NCc2cccnc2C(F)(F)F)c2n(nc(C)c2n1)C(C)C
Show InChI InChI=1S/C24H25F3N6O/c1-5-34-23-17(9-7-11-29-23)18-12-19(21-20(31-18)15(4)32-33(21)14(2)3)30-13-16-8-6-10-28-22(16)24(25,26)27/h6-12,14H,5,13H2,1-4H3,(H,30,31)
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n/an/a 0.220n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...


US Patent US11026923 (2021)

More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B


(Homo sapiens (Human))
BDBM279008
PNG
(5-(2-ethoxy-3-pyridyl)-1-isopropyl-3-methyl-N-[(5-...)
Show SMILES CCOc1ncccc1-c1cc(NCc2ncc(C)o2)c2n(nc(C)c2n1)C(C)C
Show InChI InChI=1S/C22H26N6O2/c1-6-29-22-16(8-7-9-23-22)17-10-18(24-12-19-25-11-14(4)30-19)21-20(26-17)15(5)27-28(21)13(2)3/h7-11,13H,6,12H2,1-5H3,(H,24,26)
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n/an/a 0.240n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...


US Patent US11026923 (2021)

More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B


(Homo sapiens (Human))
BDBM279050
PNG
(5-(2-ethoxy-3-pyridyl)-1-isopropyl-N-[(4-methoxy-2...)
Show SMILES CCOc1ncccc1-c1cc(NCc2cc(OC)ccn2)c2n(nc(C)c2n1)C(C)C
Show InChI InChI=1S/C24H28N6O2/c1-6-32-24-19(8-7-10-26-24)20-13-21(27-14-17-12-18(31-5)9-11-25-17)23-22(28-20)16(4)29-30(23)15(2)3/h7-13,15H,6,14H2,1-5H3,(H,27,28)
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n/an/a 0.260n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...


US Patent US11026923 (2021)

More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B


(Homo sapiens (Human))
BDBM279112
PNG
(1-isopropyl-3-methyl-5-(2-propoxy-3-pyridyl)-N-(1H...)
Show SMILES CCCOc1ncccc1-c1cc(NCc2cc[nH]n2)c2n(nc(C)c2n1)C(C)C
Show InChI InChI=1S/C22H27N7O/c1-5-11-30-22-17(7-6-9-23-22)18-12-19(24-13-16-8-10-25-27-16)21-20(26-18)15(4)28-29(21)14(2)3/h6-10,12,14H,5,11,13H2,1-4H3,(H,24,26)(H,25,27)
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n/an/a 0.260n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...


US Patent US11026923 (2021)

More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent 3',5'-cyclic phosphodiesterase 1A


(Homo sapiens (Human))
BDBM501512
PNG
(1-isopropyl-3-methyl-N-[(1-methylimidazol-4- yl)me...)
Show SMILES CCCOc1ncccc1-c1cc(NCc2cn(C)cn2)c2n(nc(C)c2n1)C(C)CC
Show InChI InChI=1S/C24H31N7O/c1-6-11-32-24-19(9-8-10-25-24)20-12-21(26-13-18-14-30(5)15-27-18)23-22(28-20)17(4)29-31(23)16(3)7-2/h8-10,12,14-16H,6-7,11,13H2,1-5H3,(H,26,28)
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n/an/a 0.260n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...


US Patent US11026923 (2021)

More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B


(Homo sapiens (Human))
BDBM501498
PNG
(5-(2-ethoxy-3-pyridyl)-3-methyl-N-[(5-methyl- 1,2,...)
Show SMILES CCOc1ncccc1-c1cc(NCc2noc(C)n2)c(NC(C)CC)c(n1)C(C)=N
Show InChI InChI=1S/C22H29N7O2/c1-6-13(3)26-21-18(25-12-19-27-15(5)31-29-19)11-17(28-20(21)14(4)23)16-9-8-10-24-22(16)30-7-2/h8-11,13,23,26H,6-7,12H2,1-5H3,(H,25,28)
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n/an/a 0.260n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...


US Patent US11026923 (2021)

More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B


(Homo sapiens (Human))
BDBM279088
PNG
(5-(2-ethoxy-3-pyridyl)-3-methyl-1-[1-methylpropyl]...)
Show SMILES CCOc1ncccc1-c1cc(NCc2cc[nH]n2)c2n(nc(C)c2n1)C(C)CC
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n/an/a 0.270n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...


US Patent US11026923 (2021)

More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B


(Homo sapiens (Human))
BDBM279068
PNG
(5-(2-ethoxy-3-pyridyl)-1-isopropyl-3-methyl-N-(2H-...)
Show SMILES CCOc1ncccc1-c1cc(NCc2nn[nH]n2)c2n(nc(C)c2n1)C(C)C
Show InChI InChI=1S/C19H23N9O/c1-5-29-19-13(7-6-8-20-19)14-9-15(21-10-16-23-26-27-24-16)18-17(22-14)12(4)25-28(18)11(2)3/h6-9,11H,5,10H2,1-4H3,(H,21,22)(H,23,24,26,27)
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n/an/a 0.310n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...


US Patent US11026923 (2021)

More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B


(Homo sapiens (Human))
BDBM501497
PNG
(5-(2-ethoxy-3-pyridyl)-3-methyl-1-[1- methylpropyl...)
Show SMILES CCOc1ncccc1-c1cc(NCc2nnn(C)n2)c(NC(C)CC)c(n1)C(C)=N
Show InChI InChI=1S/C21H29N9O/c1-6-13(3)25-20-17(24-12-18-27-29-30(5)28-18)11-16(26-19(20)14(4)22)15-9-8-10-23-21(15)31-7-2/h8-11,13,22,25H,6-7,12H2,1-5H3,(H,24,26)
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n/an/a 0.310n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...


US Patent US11026923 (2021)

More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B


(Homo sapiens (Human))
BDBM501495
PNG
(5-(2-ethoxy-3-pyridyl)-N-[(5-methoxy-3- pyridyl)me...)
Show SMILES CCOc1ncccc1-c1cc(NCc2cncc(OC)c2)c(NC(C)CC)c(n1)C(C)=N
Show InChI InChI=1S/C25H32N6O2/c1-6-16(3)30-24-22(29-14-18-11-19(32-5)15-27-13-18)12-21(31-23(24)17(4)26)20-9-8-10-28-25(20)33-7-2/h8-13,15-16,26,30H,6-7,14H2,1-5H3,(H,29,31)
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n/an/a 0.320n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...


US Patent US11026923 (2021)

More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B


(Homo sapiens (Human))
BDBM501443
PNG
(5-(2-ethoxy-3-pyridyl)-1-isopropyl-3-methyl-N- (py...)
Show SMILES CCOc1ncccc1-c1cc(NCc2ncccn2)c(NC(C)C)c(n1)C(C)=N
Show InChI InChI=1S/C22H27N7O/c1-5-30-22-16(8-6-9-26-22)17-12-18(27-13-19-24-10-7-11-25-19)21(28-14(2)3)20(29-17)15(4)23/h6-12,14,23,28H,5,13H2,1-4H3,(H,27,29)
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n/an/a 0.340n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...


US Patent US11026923 (2021)

More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B


(Homo sapiens (Human))
BDBM501373
PNG
(5-(2-ethoxy-3-pyridyl)-1-isopropyl-3-methyl-N- [(2...)
Show SMILES CCOc1ncccc1-c1cc(NCc2nnn(C)n2)c(NC(C)C)c(n1)C(C)=N
Show InChI InChI=1S/C20H27N9O/c1-6-30-20-14(8-7-9-22-20)15-10-16(23-11-17-26-28-29(5)27-17)19(24-12(2)3)18(25-15)13(4)21/h7-10,12,21,24H,6,11H2,1-5H3,(H,23,25)
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n/an/a 0.340n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...


US Patent US11026923 (2021)

More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent 3',5'-cyclic phosphodiesterase 1A


(Homo sapiens (Human))
BDBM501501
PNG
(5-(2-ethoxy-3-pyridyl)-3-methyl-1-[1- methylpropyl...)
Show SMILES CCOc1ncccc1-c1cc(NCc2cc(C)[nH]n2)c(NC(C)CC)c(n1)C(C)=N
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n/an/a 0.350n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...


US Patent US11026923 (2021)

More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B


(Homo sapiens (Human))
BDBM279055
PNG
(5-(2-ethoxy-3-pyridyl)-1-isopropyl-N-[(2-methoxy-3...)
Show SMILES CCOc1ncccc1-c1cc(NCc2cccnc2OC)c2n(nc(C)c2n1)C(C)C
Show InChI InChI=1S/C24H28N6O2/c1-6-32-24-18(10-8-12-26-24)19-13-20(27-14-17-9-7-11-25-23(17)31-5)22-21(28-19)16(4)29-30(22)15(2)3/h7-13,15H,6,14H2,1-5H3,(H,27,28)
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n/an/a 0.360n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...


US Patent US11026923 (2021)

More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B


(Homo sapiens (Human))
BDBM279077
PNG
(3-[[[5-(2-ethoxy-3-pyridyl)-1-isopropyl-3-methyl-p...)
Show SMILES CCOc1ncccc1-c1cc(NCc2cccn(C)c2=O)c2n(nc(C)c2n1)C(C)C
Show InChI InChI=1S/C24H28N6O2/c1-6-32-23-18(10-7-11-25-23)19-13-20(26-14-17-9-8-12-29(5)24(17)31)22-21(27-19)16(4)28-30(22)15(2)3/h7-13,15H,6,14H2,1-5H3,(H,26,27)
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n/an/a 0.360n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...


US Patent US11026923 (2021)

More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent 3',5'-cyclic phosphodiesterase 1A


(Homo sapiens (Human))
BDBM279024
PNG
(N-[(1,5-dimethylpyrazol-3-yl)methyl]-5-(2-ethoxy-3...)
Show SMILES CCOc1ncccc1-c1cc(NCc2cc(C)n(C)n2)c2n(nc(C)c2n1)C(C)C
Show InChI InChI=1S/C23H29N7O/c1-7-31-23-18(9-8-10-24-23)19-12-20(25-13-17-11-15(4)29(6)28-17)22-21(26-19)16(5)27-30(22)14(2)3/h8-12,14H,7,13H2,1-6H3,(H,25,26)
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n/an/a 0.390n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...


US Patent US11026923 (2021)

More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B


(Homo sapiens (Human))
BDBM279069
PNG
(5-(2-ethoxy-3-pyridyl)-1-isopropyl-3-methyl-N-(2-p...)
Show SMILES CCOc1ncccc1-c1cc(NCc2ccccn2)c2n(nc(C)c2n1)C(C)C
Show InChI InChI=1S/C23H26N6O/c1-5-30-23-18(10-8-12-25-23)19-13-20(26-14-17-9-6-7-11-24-17)22-21(27-19)16(4)28-29(22)15(2)3/h6-13,15H,5,14H2,1-4H3,(H,26,27)
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n/an/a 0.390n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...


US Patent US11026923 (2021)

More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent 3',5'-cyclic phosphodiesterase 1A


(Homo sapiens (Human))
BDBM279114
PNG
(1-isopropyl-3-methyl-N-[(1-methyl-1,2,4-triazol-3-...)
Show SMILES CCCOc1ncccc1-c1cc(NCc2ncn(C)n2)c2n(nc(C)c2n1)C(C)C
Show InChI InChI=1S/C22H28N8O/c1-6-10-31-22-16(8-7-9-23-22)17-11-18(24-12-19-25-13-29(5)28-19)21-20(26-17)15(4)27-30(21)14(2)3/h7-9,11,13-14H,6,10,12H2,1-5H3,(H,24,26)
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n/an/a 0.410n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...


US Patent US11026923 (2021)

More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B


(Homo sapiens (Human))
BDBM279003
PNG
(5-(2-ethoxy-3-pyridyl)-1-isopropyl-3-methyl-N-[(5-...)
Show SMILES CCOc1ncccc1-c1cc(NCc2nnc(C)s2)c2n(nc(C)c2n1)C(C)C
Show InChI InChI=1S/C21H25N7OS/c1-6-29-21-15(8-7-9-22-21)16-10-17(23-11-18-26-25-14(5)30-18)20-19(24-16)13(4)27-28(20)12(2)3/h7-10,12H,6,11H2,1-5H3,(H,23,24)
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n/an/a 0.410n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...


US Patent US11026923 (2021)

More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B


(Homo sapiens (Human))
BDBM279016
PNG
(5-(2-ethoxypyridin-3-yl)-1-isopropyl-3-methyl-N-((...)
Show SMILES CCOc1ncccc1-c1cc(NCc2c[nH]c(C)n2)c2n(nc(C)c2n1)C(C)C
Show InChI InChI=1S/C22H27N7O/c1-6-30-22-17(8-7-9-23-22)18-10-19(25-12-16-11-24-15(5)26-16)21-20(27-18)14(4)28-29(21)13(2)3/h7-11,13H,6,12H2,1-5H3,(H,24,26)(H,25,27)
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n/an/a 0.420n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...


US Patent US11026923 (2021)

More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B


(Homo sapiens (Human))
BDBM279087
PNG
(5-(2-ethoxy-3-pyridyl)-1-isopropyl-N-[(3-methoxy-2...)
Show SMILES CCOc1ncccc1-c1cc(NCc2ncccc2OC)c2n(nc(C)c2n1)C(C)C
Show InChI InChI=1S/C24H28N6O2/c1-6-32-24-17(9-7-12-26-24)18-13-19(27-14-20-21(31-5)10-8-11-25-20)23-22(28-18)16(4)29-30(23)15(2)3/h7-13,15H,6,14H2,1-5H3,(H,27,28)
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n/an/a 0.420n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...


US Patent US11026923 (2021)

More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B


(Homo sapiens (Human))
BDBM279009
PNG
(5-(2-ethoxy-3-pyridyl)-1-isopropyl-3-methyl-N-(1H-...)
Show SMILES CCOc1ncccc1-c1cc(NCc2cc[nH]n2)c2n(nc(C)c2n1)C(C)C
Show InChI InChI=1S/C21H25N7O/c1-5-29-21-16(7-6-9-22-21)17-11-18(23-12-15-8-10-24-26-15)20-19(25-17)14(4)27-28(20)13(2)3/h6-11,13H,5,12H2,1-4H3,(H,23,25)(H,24,26)
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n/an/a 0.430n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...


US Patent US11026923 (2021)

More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B


(Homo sapiens (Human))
BDBM279007
PNG
(5-(2-ethoxy-3-pyridyl)-1-isopropyl-3-methyl-N-[(2-...)
Show SMILES CCOc1ncccc1-c1cc(NCc2coc(C)n2)c2n(nc(C)c2n1)C(C)C
Show InChI InChI=1S/C22H26N6O2/c1-6-29-22-17(8-7-9-23-22)18-10-19(24-11-16-12-30-15(5)25-16)21-20(26-18)14(4)27-28(21)13(2)3/h7-10,12-13H,6,11H2,1-5H3,(H,24,26)
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n/an/a 0.430n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...


US Patent US11026923 (2021)

More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B


(Homo sapiens (Human))
BDBM278991
PNG
(5-(2-ethoxy-3-pyridyl)-1-isopropyl-N-[(1-methylimi...)
Show SMILES CCOc1ncccc1-c1cc(NCc2cn(C)cn2)c2n(ncc2n1)C(C)C
Show InChI InChI=1S/C21H25N7O/c1-5-29-21-16(7-6-8-22-21)17-9-18(23-10-15-12-27(4)13-24-15)20-19(26-17)11-25-28(20)14(2)3/h6-9,11-14H,5,10H2,1-4H3,(H,23,26)
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n/an/a 0.440n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...


US Patent US11026923 (2021)

More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B


(Homo sapiens (Human))
BDBM279075
PNG
(5-(2-ethoxy-3-pyridyl)-1-isopropyl-N-[(5-methoxy-3...)
Show SMILES CCOc1ncccc1-c1cc(NCc2cncc(OC)c2)c2n(nc(C)c2n1)C(C)C
Show InChI InChI=1S/C24H28N6O2/c1-6-32-24-19(8-7-9-26-24)20-11-21(27-13-17-10-18(31-5)14-25-12-17)23-22(28-20)16(4)29-30(23)15(2)3/h7-12,14-15H,6,13H2,1-5H3,(H,27,28)
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n/an/a 0.450n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...


US Patent US11026923 (2021)

More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C


(Homo sapiens (Human))
BDBM501501
PNG
(5-(2-ethoxy-3-pyridyl)-3-methyl-1-[1- methylpropyl...)
Show SMILES CCOc1ncccc1-c1cc(NCc2cc(C)[nH]n2)c(NC(C)CC)c(n1)C(C)=N
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n/an/a 0.460n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...


US Patent US11026923 (2021)

More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent 3',5'-cyclic phosphodiesterase 1A


(Homo sapiens (Human))
BDBM278972
PNG
(5-(2-ethoxy-3-pyridyl)-1-isopropyl-3-methyl-N-[(5-...)
Show SMILES CCOc1ncccc1-c1cc(NCc2ncc(C)s2)c2n(nc(C)c2n1)C(C)C
Show InChI InChI=1S/C22H26N6OS/c1-6-29-22-16(8-7-9-23-22)17-10-18(24-12-19-25-11-14(4)30-19)21-20(26-17)15(5)27-28(21)13(2)3/h7-11,13H,6,12H2,1-5H3,(H,24,26)
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n/an/a 0.460n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...


US Patent US11026923 (2021)

More data for this
Ligand-Target Pair
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B


(Homo sapiens (Human))
BDBM501491
PNG
(5-(2-ethoxy-3-pyridyl)-3-methyl-1-[1- methylpropyl...)
Show SMILES CCOc1ncccc1-c1cc(NCC(=N)\N=C/N)c(NC(C)CC)c(n1)C(C)=N
Show InChI InChI=1S/C21H30N8O/c1-5-13(3)28-20-17(26-11-18(24)27-12-22)10-16(29-19(20)14(4)23)15-8-7-9-25-21(15)30-6-2/h7-10,12-13,23,28H,5-6,11H2,1-4H3,(H,26,29)(H3,22,24,27)
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n/an/a 0.470n/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 uL samples containing a fixed amount of the PDE1 enzyme (suff...


US Patent US11026923 (2021)

More data for this
Ligand-Target Pair
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* indicates data uncertainty>20%