Compile Data Set for Download or QSAR
maximum 50k data
Found 14 Enz. Inhib. hit(s) with all data for entry = 9941
TargetBromodomain-containing protein 2 [74-94](Homo sapiens (Human))
St. Jude Children'S Research Hospital

US Patent
LigandPNGBDBM205429( (R)-JQ1 (3) | US10407441, Compound (R)-JQ1 | US10...)
Affinity DataKd:  89nMAssay Description:Binding of compounds to BRD2 was monitored using an ITC200 (Microcal, Piscataway, N.J.). Either Brd2.1 (74-194) or Brd2.2 (348-455) was dialyzed over...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBromodomain-containing protein 2 [74-94](Homo sapiens (Human))
St. Jude Children'S Research Hospital

US Patent
LigandPNGBDBM50452551(CHEMBL4209110 | US11028051, Cmpd 50)
Affinity DataKd:  2.19E+3nMAssay Description:Binding of compounds to BRD2 was monitored using an ITC200 (Microcal, Piscataway, N.J.). Either Brd2.1 (74-194) or Brd2.2 (348-455) was dialyzed over...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetBromodomain-containing protein 2 [74-94](Homo sapiens (Human))
St. Jude Children'S Research Hospital

US Patent
LigandPNGBDBM50452554(CHEMBL4207106 | US11028051, Cmpd 51)
Affinity DataKd:  162nMAssay Description:Binding of compounds to BRD2 was monitored using an ITC200 (Microcal, Piscataway, N.J.). Either Brd2.1 (74-194) or Brd2.2 (348-455) was dialyzed over...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 2 [74-94](Homo sapiens (Human))
St. Jude Children'S Research Hospital

US Patent
LigandPNGBDBM50452552(CHEMBL4205876 | US11028051, Cmpd 52)
Affinity DataKd:  61nMAssay Description:Binding of compounds to BRD2 was monitored using an ITC200 (Microcal, Piscataway, N.J.). Either Brd2.1 (74-194) or Brd2.2 (348-455) was dialyzed over...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 2 [74-94](Homo sapiens (Human))
St. Jude Children'S Research Hospital

US Patent
LigandPNGBDBM50452556(CHEMBL4210405 | US11028051, Cmpd 53)
Affinity DataKd:  72nMAssay Description:Binding of compounds to BRD2 was monitored using an ITC200 (Microcal, Piscataway, N.J.). Either Brd2.1 (74-194) or Brd2.2 (348-455) was dialyzed over...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 2 [74-94](Homo sapiens (Human))
St. Jude Children'S Research Hospital

US Patent
LigandPNGBDBM50452553(CHEMBL4202664 | US11028051, Cmpd 54)
Affinity DataKd:  131nMAssay Description:Binding of compounds to BRD2 was monitored using an ITC200 (Microcal, Piscataway, N.J.). Either Brd2.1 (74-194) or Brd2.2 (348-455) was dialyzed over...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 2 [348-455](Homo sapiens (Human))
St. Jude Children'S Research Hospital

US Patent
LigandPNGBDBM50452557(CHEMBL4206677 | US11028051, Cmpd 55)
Affinity DataKd:  20nMAssay Description:Binding of compounds to BRD2 was monitored using an ITC200 (Microcal, Piscataway, N.J.). Either Brd2.1 (74-194) or Brd2.2 (348-455) was dialyzed over...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 2 [348-455](Homo sapiens (Human))
St. Jude Children'S Research Hospital

US Patent
LigandPNGBDBM205429( (R)-JQ1 (3) | US10407441, Compound (R)-JQ1 | US10...)
Affinity DataKd:  112nMAssay Description:Binding of compounds to BRD2 was monitored using an ITC200 (Microcal, Piscataway, N.J.). Either Brd2.1 (74-194) or Brd2.2 (348-455) was dialyzed over...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBromodomain-containing protein 2 [348-455](Homo sapiens (Human))
St. Jude Children'S Research Hospital

US Patent
LigandPNGBDBM50452551(CHEMBL4209110 | US11028051, Cmpd 50)
Affinity DataKd:  280nMAssay Description:Binding of compounds to BRD2 was monitored using an ITC200 (Microcal, Piscataway, N.J.). Either Brd2.1 (74-194) or Brd2.2 (348-455) was dialyzed over...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetBromodomain-containing protein 2 [348-455](Homo sapiens (Human))
St. Jude Children'S Research Hospital

US Patent
LigandPNGBDBM50452554(CHEMBL4207106 | US11028051, Cmpd 51)
Affinity DataKd:  300nMAssay Description:Binding of compounds to BRD2 was monitored using an ITC200 (Microcal, Piscataway, N.J.). Either Brd2.1 (74-194) or Brd2.2 (348-455) was dialyzed over...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 2 [348-455](Homo sapiens (Human))
St. Jude Children'S Research Hospital

US Patent
LigandPNGBDBM50452552(CHEMBL4205876 | US11028051, Cmpd 52)
Affinity DataKd:  21nMAssay Description:Binding of compounds to BRD2 was monitored using an ITC200 (Microcal, Piscataway, N.J.). Either Brd2.1 (74-194) or Brd2.2 (348-455) was dialyzed over...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 2 [348-455](Homo sapiens (Human))
St. Jude Children'S Research Hospital

US Patent
LigandPNGBDBM50452556(CHEMBL4210405 | US11028051, Cmpd 53)
Affinity DataKd:  17nMAssay Description:Binding of compounds to BRD2 was monitored using an ITC200 (Microcal, Piscataway, N.J.). Either Brd2.1 (74-194) or Brd2.2 (348-455) was dialyzed over...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 2 [348-455](Homo sapiens (Human))
St. Jude Children'S Research Hospital

US Patent
LigandPNGBDBM50452553(CHEMBL4202664 | US11028051, Cmpd 54)
Affinity DataKd:  36nMAssay Description:Binding of compounds to BRD2 was monitored using an ITC200 (Microcal, Piscataway, N.J.). Either Brd2.1 (74-194) or Brd2.2 (348-455) was dialyzed over...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 2 [74-94](Homo sapiens (Human))
St. Jude Children'S Research Hospital

US Patent
LigandPNGBDBM50452557(CHEMBL4206677 | US11028051, Cmpd 55)
Affinity DataKd:  92nMAssay Description:Binding of compounds to BRD2 was monitored using an ITC200 (Microcal, Piscataway, N.J.). Either Brd2.1 (74-194) or Brd2.2 (348-455) was dialyzed over...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent