Affinity Data by Patent

Patent code US11040984

Found 22 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
EGFR (del 746-750) (Homo sapiens (Human))	BDBM504402 (US11040984, Compound 2) Show SMILES Show InChI	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	16.5	n/a	n/a	n/a	n/a	n/a	n/a
MEDSHINE DISCOVERY INC. US Patent					Assay Description Buffer formulation: a buffer consisted of 50 mM HEPES (pH 7.5), 0.01% BSA, 5 mM MgCl2, 0.1 mM Orthovanadate. After the buffer was formulated, an enzy...				US Patent US11040984 (2021)
MEDSHINE DISCOVERY INC. US Patent					More data for this Ligand-Target Pair
EGFR (del 746-750) (Homo sapiens (Human))	BDBM504415 (US11040984, Compound 30) Show SMILES Show InChI	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0520	n/a	n/a	n/a	n/a	n/a	n/a
MEDSHINE DISCOVERY INC. US Patent					Assay Description Buffer formulation: a buffer consisted of 50 mM HEPES (pH 7.5), 0.01% BSA, 5 mM MgCl2, 0.1 mM Orthovanadate. After the buffer was formulated, an enzy...				US Patent US11040984 (2021)
MEDSHINE DISCOVERY INC. US Patent					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM504415 (US11040984, Compound 30) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0210	n/a	n/a	n/a	n/a	n/a	n/a
MEDSHINE DISCOVERY INC. US Patent					Assay Description Buffer formulation: a buffer consisted of 50 mM HEPES (pH 7.5), 0.01% BSA, 5 mM MgCl2, 0.1 mM Orthovanadate. After the buffer was formulated, an enzy...				US Patent US11040984 (2021)
MEDSHINE DISCOVERY INC. US Patent					More data for this Ligand-Target Pair
EGFR (del 746-750) (Homo sapiens (Human))	BDBM504411 (US11040984, Compound 13) Show SMILES Show InChI	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0520	n/a	n/a	n/a	n/a	n/a	n/a
MEDSHINE DISCOVERY INC. US Patent					Assay Description Buffer formulation: a buffer consisted of 50 mM HEPES (pH 7.5), 0.01% BSA, 5 mM MgCl2, 0.1 mM Orthovanadate. After the buffer was formulated, an enzy...				US Patent US11040984 (2021)
MEDSHINE DISCOVERY INC. US Patent					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM504416 (US11040984, Compound 33) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.114	n/a	n/a	n/a	n/a	n/a	n/a
MEDSHINE DISCOVERY INC. US Patent					Assay Description Buffer formulation: a buffer consisted of 50 mM HEPES (pH 7.5), 0.01% BSA, 5 mM MgCl2, 0.1 mM Orthovanadate. After the buffer was formulated, an enzy...				US Patent US11040984 (2021)
MEDSHINE DISCOVERY INC. US Patent					More data for this Ligand-Target Pair
EGFR (del 746-750) (Homo sapiens (Human))	BDBM504405 (US11040984, Compound 4) Show SMILES Show InChI	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	55.4	n/a	n/a	n/a	n/a	n/a	n/a
MEDSHINE DISCOVERY INC. US Patent					Assay Description Buffer formulation: a buffer consisted of 50 mM HEPES (pH 7.5), 0.01% BSA, 5 mM MgCl2, 0.1 mM Orthovanadate. After the buffer was formulated, an enzy...				US Patent US11040984 (2021)
MEDSHINE DISCOVERY INC. US Patent					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM504412 (US11040984, Compound 18) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.0150	n/a	n/a	n/a	n/a	n/a	n/a
MEDSHINE DISCOVERY INC. US Patent					Assay Description Buffer formulation: a buffer consisted of 50 mM HEPES (pH 7.5), 0.01% BSA, 5 mM MgCl2, 0.1 mM Orthovanadate. After the buffer was formulated, an enzy...				US Patent US11040984 (2021)
MEDSHINE DISCOVERY INC. US Patent					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM504413 (US11040984, Compound 23) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0380	n/a	n/a	n/a	n/a	n/a	n/a
MEDSHINE DISCOVERY INC. US Patent					Assay Description Buffer formulation: a buffer consisted of 50 mM HEPES (pH 7.5), 0.01% BSA, 5 mM MgCl2, 0.1 mM Orthovanadate. After the buffer was formulated, an enzy...				US Patent US11040984 (2021)
MEDSHINE DISCOVERY INC. US Patent					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM504410 (US11040984, Compound 12) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0170	n/a	n/a	n/a	n/a	n/a	n/a
MEDSHINE DISCOVERY INC. US Patent					Assay Description Buffer formulation: a buffer consisted of 50 mM HEPES (pH 7.5), 0.01% BSA, 5 mM MgCl2, 0.1 mM Orthovanadate. After the buffer was formulated, an enzy...				US Patent US11040984 (2021)
MEDSHINE DISCOVERY INC. US Patent					More data for this Ligand-Target Pair
EGFR (del 746-750) (Homo sapiens (Human))	BDBM504412 (US11040984, Compound 18) Show SMILES Show InChI	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0500	n/a	n/a	n/a	n/a	n/a	n/a
MEDSHINE DISCOVERY INC. US Patent					Assay Description Buffer formulation: a buffer consisted of 50 mM HEPES (pH 7.5), 0.01% BSA, 5 mM MgCl2, 0.1 mM Orthovanadate. After the buffer was formulated, an enzy...				US Patent US11040984 (2021)
MEDSHINE DISCOVERY INC. US Patent					More data for this Ligand-Target Pair
EGFR (del 746-750) (Homo sapiens (Human))	BDBM504416 (US11040984, Compound 33) Show SMILES Show InChI	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.290	n/a	n/a	n/a	n/a	n/a	n/a
MEDSHINE DISCOVERY INC. US Patent					Assay Description Buffer formulation: a buffer consisted of 50 mM HEPES (pH 7.5), 0.01% BSA, 5 mM MgCl2, 0.1 mM Orthovanadate. After the buffer was formulated, an enzy...				US Patent US11040984 (2021)
MEDSHINE DISCOVERY INC. US Patent					More data for this Ligand-Target Pair
Epidermal growth factor receptor(L858R) (Homo sapiens (Human))	BDBM504403 (US11040984, Compound 3) Show SMILES Show InChI	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
MEDSHINE DISCOVERY INC. US Patent					Assay Description Buffer formulation: a buffer consisted of 50 mM HEPES (pH 7.5), 0.01% BSA, 5 mM MgCl2, 0.1 mM Orthovanadate. After the buffer was formulated, an enzy...				US Patent US11040984 (2021)
MEDSHINE DISCOVERY INC. US Patent					More data for this Ligand-Target Pair
Epidermal growth factor receptor(L858R) (Homo sapiens (Human))	BDBM504405 (US11040984, Compound 4) Show SMILES Show InChI	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	30.1	n/a	n/a	n/a	n/a	n/a	n/a
MEDSHINE DISCOVERY INC. US Patent					Assay Description Buffer formulation: a buffer consisted of 50 mM HEPES (pH 7.5), 0.01% BSA, 5 mM MgCl2, 0.1 mM Orthovanadate. After the buffer was formulated, an enzy...				US Patent US11040984 (2021)
MEDSHINE DISCOVERY INC. US Patent					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM504408 (US11040984, Compound 6) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.0150	n/a	n/a	n/a	n/a	n/a	n/a
MEDSHINE DISCOVERY INC. US Patent					Assay Description Buffer formulation: a buffer consisted of 50 mM HEPES (pH 7.5), 0.01% BSA, 5 mM MgCl2, 0.1 mM Orthovanadate. After the buffer was formulated, an enzy...				US Patent US11040984 (2021)
MEDSHINE DISCOVERY INC. US Patent					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM504411 (US11040984, Compound 13) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0160	n/a	n/a	n/a	n/a	n/a	n/a
MEDSHINE DISCOVERY INC. US Patent					Assay Description Buffer formulation: a buffer consisted of 50 mM HEPES (pH 7.5), 0.01% BSA, 5 mM MgCl2, 0.1 mM Orthovanadate. After the buffer was formulated, an enzy...				US Patent US11040984 (2021)
MEDSHINE DISCOVERY INC. US Patent					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM504414 (US11040984, Compound 25) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0220	n/a	n/a	n/a	n/a	n/a	n/a
MEDSHINE DISCOVERY INC. US Patent					Assay Description Buffer formulation: a buffer consisted of 50 mM HEPES (pH 7.5), 0.01% BSA, 5 mM MgCl2, 0.1 mM Orthovanadate. After the buffer was formulated, an enzy...				US Patent US11040984 (2021)
MEDSHINE DISCOVERY INC. US Patent					More data for this Ligand-Target Pair
EGFR (del 746-750) (Homo sapiens (Human))	BDBM504414 (US11040984, Compound 25) Show SMILES Show InChI	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0690	n/a	n/a	n/a	n/a	n/a	n/a
MEDSHINE DISCOVERY INC. US Patent					Assay Description Buffer formulation: a buffer consisted of 50 mM HEPES (pH 7.5), 0.01% BSA, 5 mM MgCl2, 0.1 mM Orthovanadate. After the buffer was formulated, an enzy...				US Patent US11040984 (2021)
MEDSHINE DISCOVERY INC. US Patent					More data for this Ligand-Target Pair
Epidermal growth factor receptor(L858R) (Homo sapiens (Human))	BDBM504402 (US11040984, Compound 2) Show SMILES Show InChI	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	48.1	n/a	n/a	n/a	n/a	n/a	n/a
MEDSHINE DISCOVERY INC. US Patent					Assay Description Buffer formulation: a buffer consisted of 50 mM HEPES (pH 7.5), 0.01% BSA, 5 mM MgCl2, 0.1 mM Orthovanadate. After the buffer was formulated, an enzy...				US Patent US11040984 (2021)
MEDSHINE DISCOVERY INC. US Patent					More data for this Ligand-Target Pair
EGFR (del 746-750) (Homo sapiens (Human))	BDBM504408 (US11040984, Compound 6) Show SMILES Show InChI	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0700	n/a	n/a	n/a	n/a	n/a	n/a
MEDSHINE DISCOVERY INC. US Patent					Assay Description Buffer formulation: a buffer consisted of 50 mM HEPES (pH 7.5), 0.01% BSA, 5 mM MgCl2, 0.1 mM Orthovanadate. After the buffer was formulated, an enzy...				US Patent US11040984 (2021)
MEDSHINE DISCOVERY INC. US Patent					More data for this Ligand-Target Pair
EGFR (del 746-750) (Homo sapiens (Human))	BDBM504410 (US11040984, Compound 12) Show SMILES Show InChI	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0850	n/a	n/a	n/a	n/a	n/a	n/a
MEDSHINE DISCOVERY INC. US Patent					Assay Description Buffer formulation: a buffer consisted of 50 mM HEPES (pH 7.5), 0.01% BSA, 5 mM MgCl2, 0.1 mM Orthovanadate. After the buffer was formulated, an enzy...				US Patent US11040984 (2021)
MEDSHINE DISCOVERY INC. US Patent					More data for this Ligand-Target Pair
EGFR (del 746-750) (Homo sapiens (Human))	BDBM504413 (US11040984, Compound 23) Show SMILES Show InChI	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.170	n/a	n/a	n/a	n/a	n/a	n/a
MEDSHINE DISCOVERY INC. US Patent					Assay Description Buffer formulation: a buffer consisted of 50 mM HEPES (pH 7.5), 0.01% BSA, 5 mM MgCl2, 0.1 mM Orthovanadate. After the buffer was formulated, an enzy...				US Patent US11040984 (2021)
MEDSHINE DISCOVERY INC. US Patent					More data for this Ligand-Target Pair
EGFR (del 746-750) (Homo sapiens (Human))	BDBM504403 (US11040984, Compound 3) Show SMILES Show InChI	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0200	n/a	n/a	n/a	n/a	n/a	n/a
MEDSHINE DISCOVERY INC. US Patent					Assay Description Buffer formulation: a buffer consisted of 50 mM HEPES (pH 7.5), 0.01% BSA, 5 mM MgCl2, 0.1 mM Orthovanadate. After the buffer was formulated, an enzy...				US Patent US11040984 (2021)
MEDSHINE DISCOVERY INC. US Patent					More data for this Ligand-Target Pair

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* indicates data uncertainty>20%