Compile Data Set for Download or QSAR
maximum 50k data
Found 336 Enz. Inhib. hit(s) with all data for entry = 10370
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
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LigandPNGBDBM531233((Z)-Methyl 3-(((4-(4-(2-((2-hydroxyethyl)amino)-2-...)
Affinity DataKi:  2.5nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA, 1 mM DTT and 2 mM MnCl2. The inhibitory activities of compoun...More data for this Ligand-Target Pair
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TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
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LigandPNGBDBM445247(US10669235, Example 38 | US11208381, Example 38)
Affinity DataKi:  3.26nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
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LigandPNGBDBM445242(US10669235, Example 33 | US11208381, Example 33)
Affinity DataKi:  3.56nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
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LigandPNGBDBM445257(US10669235, Example 48 | US11208381, Example 48)
Affinity DataKi:  3.68nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
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LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)
Affinity DataKi:  3.80nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
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US Patent
LigandPNGBDBM445255(US10669235, Example 46 | US11208381, Example 46)
Affinity DataKi:  4.15nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
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LigandPNGBDBM445247(US10669235, Example 38 | US11208381, Example 38)
Affinity DataKi:  4.79nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
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LigandPNGBDBM445240(US10669235, Example 31 | US11208381, Example 31)
Affinity DataKi:  4.83nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
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LigandPNGBDBM445240(US10669235, Example 31 | US11208381, Example 31)
Affinity DataKi:  4.96nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
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LigandPNGBDBM531233((Z)-Methyl 3-(((4-(4-(2-((2-hydroxyethyl)amino)-2-...)
Affinity DataKi:  5nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
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LigandPNGBDBM531233((Z)-Methyl 3-(((4-(4-(2-((2-hydroxyethyl)amino)-2-...)
Affinity DataKi:  5nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
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LigandPNGBDBM531233((Z)-Methyl 3-(((4-(4-(2-((2-hydroxyethyl)amino)-2-...)
Affinity DataKi:  5nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
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LigandPNGBDBM445241(US10669235, Example 32 | US11208381, Example 32)
Affinity DataKi:  5.02nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
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LigandPNGBDBM445220(US10669235, Example 11 | US11208381, Example 11)
Affinity DataKi:  5.06nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
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LigandPNGBDBM445226(US10669235, Example 17 | US11208381, Example 17)
Affinity DataKi:  5.31nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA, 1 mM DTT and 2 mM MnCl2. The inhibitory activities of compoun...More data for this Ligand-Target Pair
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TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
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LigandPNGBDBM445223(US10669235, Example 14 | US10669235, Example 50 | ...)
Affinity DataKi:  5.51nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA, 1 mM DTT and 2 mM MnCl2. The inhibitory activities of compoun...More data for this Ligand-Target Pair
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TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
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LigandPNGBDBM445223(US10669235, Example 14 | US10669235, Example 50 | ...)
Affinity DataKi:  5.51nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA, 1 mM DTT and 2 mM MnCl2. The inhibitory activities of compoun...More data for this Ligand-Target Pair
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TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
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LigandPNGBDBM445216(US10669235, Example 7 | US11208381, Example 7)
Affinity DataKi:  5.76nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
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LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)
Affinity DataKi:  5.90nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA, 1 mM DTT and 2 mM MnCl2. The inhibitory activities of compoun...More data for this Ligand-Target Pair
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TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
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LigandPNGBDBM445230(US10669235, Example 21 | US11208381, Example 21)
Affinity DataKi:  6.11nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
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LigandPNGBDBM445221(US10669235, Example 12 | US11208381, Example 12)
Affinity DataKi:  6.38nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
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LigandPNGBDBM445226(US10669235, Example 17 | US11208381, Example 17)
Affinity DataKi:  6.40nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
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LigandPNGBDBM445228(US10669235, Example 19 | US11208381, Example 19)
Affinity DataKi:  6.55nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
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LigandPNGBDBM445255(US10669235, Example 46 | US11208381, Example 46)
Affinity DataKi:  6.65nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
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LigandPNGBDBM445241(US10669235, Example 32 | US11208381, Example 32)
Affinity DataKi:  6.65nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA, 1 mM DTT and 2 mM MnCl2. The inhibitory activities of compoun...More data for this Ligand-Target Pair
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TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
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LigandPNGBDBM445242(US10669235, Example 33 | US11208381, Example 33)
Affinity DataKi:  6.82nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
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LigandPNGBDBM445255(US10669235, Example 46 | US11208381, Example 46)
Affinity DataKi:  6.86nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
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LigandPNGBDBM445212(US10669235, Example 3 | US11208381, Example 3)
Affinity DataKi:  6.86nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
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LigandPNGBDBM445247(US10669235, Example 38 | US11208381, Example 38)
Affinity DataKi:  6.93nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA, 1 mM DTT and 2 mM MnCl2. The inhibitory activities of compoun...More data for this Ligand-Target Pair
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TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
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LigandPNGBDBM445222(US10669235, Example 13 | US10669235, Example 49 | ...)
Affinity DataKi:  7.16nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA, 1 mM DTT and 2 mM MnCl2. The inhibitory activities of compoun...More data for this Ligand-Target Pair
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TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
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LigandPNGBDBM445222(US10669235, Example 13 | US10669235, Example 49 | ...)
Affinity DataKi:  7.16nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA, 1 mM DTT and 2 mM MnCl2. The inhibitory activities of compoun...More data for this Ligand-Target Pair
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TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
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LigandPNGBDBM445215(US10669235, Example 6 | US11208381, Example 6)
Affinity DataKi:  7.35nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA, 1 mM DTT and 2 mM MnCl2. The inhibitory activities of compoun...More data for this Ligand-Target Pair
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TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
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LigandPNGBDBM445241(US10669235, Example 32 | US11208381, Example 32)
Affinity DataKi:  7.38nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
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LigandPNGBDBM445242(US10669235, Example 33 | US11208381, Example 33)
Affinity DataKi:  7.40nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA, 1 mM DTT and 2 mM MnCl2. The inhibitory activities of compoun...More data for this Ligand-Target Pair
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TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
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LigandPNGBDBM445247(US10669235, Example 38 | US11208381, Example 38)
Affinity DataKi:  7.53nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
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LigandPNGBDBM445246(US10669235, Example 37 | US11208381, Example 37)
Affinity DataKi:  7.54nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
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LigandPNGBDBM445241(US10669235, Example 32 | US11208381, Example 32)
Affinity DataKi:  7.56nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
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LigandPNGBDBM445255(US10669235, Example 46 | US11208381, Example 46)
Affinity DataKi:  7.78nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA, 1 mM DTT and 2 mM MnCl2. The inhibitory activities of compoun...More data for this Ligand-Target Pair
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TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
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LigandPNGBDBM445226(US10669235, Example 17 | US11208381, Example 17)
Affinity DataKi:  7.81nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
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LigandPNGBDBM445216(US10669235, Example 7 | US11208381, Example 7)
Affinity DataKi:  7.82nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
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LigandPNGBDBM445218(US10669235, Example 9 | US11208381, Example 9)
Affinity DataKi:  7.89nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
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LigandPNGBDBM531233((Z)-Methyl 3-(((4-(4-(2-((2-hydroxyethyl)amino)-2-...)
Affinity DataKi:  7.90nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
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LigandPNGBDBM445255(US10669235, Example 46 | US11208381, Example 46)
Affinity DataKi:  7.92nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
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LigandPNGBDBM445227(US10669235, Example 18 | US11208381, Example 18)
Affinity DataKi:  7.99nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
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LigandPNGBDBM445239(US10669235, Example 30 | US11208381, Example 30)
Affinity DataKi:  8nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
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LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)
Affinity DataKi:  8nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
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LigandPNGBDBM445213(US10669235, Example 4 | US11208381, Example 4)
Affinity DataKi:  8.07nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA, 1 mM DTT and 2 mM MnCl2. The inhibitory activities of compoun...More data for this Ligand-Target Pair
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TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
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LigandPNGBDBM445217(US10669235, Example 8 | US11208381, Example 8)
Affinity DataKi:  8.12nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
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LigandPNGBDBM445228(US10669235, Example 19 | US11208381, Example 19)
Affinity DataKi:  8.35nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
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LigandPNGBDBM445218(US10669235, Example 9 | US11208381, Example 9)
Affinity DataKi:  8.36nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
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