Compile Data Set for Download or QSAR
maximum 50k data
Found 10 Enz. Inhib. hit(s) with all data for entry = 6163
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM50314762(5-methyl-2-(methylthio)-3-(phenylsulfonyl)-6,7,8,9...)
Affinity DataKi:  0.440nM ΔG°:  -54.3kJ/mole IC50:  0.948nMpH: 7.4 T: 2°CAssay Description:Determination of tested compounds binding with 5-HT6 receptors was carried out according to the method described in [Monsma F J Jr, Shen Y, Ward R P,...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM50314759(2-(methylthio)-3-(phenylsulfonyl)-7,8-dihydro-6H-c...)
Affinity DataKi:  0.458nM ΔG°:  -54.2kJ/mole IC50:  0.986nMpH: 7.4 T: 2°CAssay Description:Determination of tested compounds binding with 5-HT6 receptors was carried out according to the method described in [Monsma F J Jr, Shen Y, Ward R P,...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM50314760(2-(methylthio)-3-(phenylsulfonyl)-6,7,8,9-tetrahyd...)
Affinity DataKi:  0.549nM ΔG°:  -53.7kJ/mole IC50:  1.18nMpH: 7.4 T: 2°CAssay Description:Determination of tested compounds binding with 5-HT6 receptors was carried out according to the method described in [Monsma F J Jr, Shen Y, Ward R P,...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM50314763(9-methyl-2-(methylthio)-3-(phenylsulfonyl)-5,6,7,8...)
Affinity DataKi:  0.680nM ΔG°:  -53.2kJ/mole IC50:  1.46nMpH: 7.4 T: 2°CAssay Description:Determination of tested compounds binding with 5-HT6 receptors was carried out according to the method described in [Monsma F J Jr, Shen Y, Ward R P,...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM50314761(2-Methylsulfanyl-3-phenylsulfonyl-5,6,7,8-tetrahyd...)
Affinity DataKi:  7.97nM ΔG°:  -47.0kJ/mole IC50:  17.2nMpH: 7.4 T: 2°CAssay Description:Determination of tested compounds binding with 5-HT6 receptors was carried out according to the method described in [Monsma F J Jr, Shen Y, Ward R P,...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM50314763(9-methyl-2-(methylthio)-3-(phenylsulfonyl)-5,6,7,8...)
Affinity DataIC50:  7.80nMAssay Description:Compounds of general formulas 1 and 2 were tested for their ability to prevent 5-HT6 receptors activation by serotonin. HEK 293 cells (cells of human...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM50314759(2-(methylthio)-3-(phenylsulfonyl)-7,8-dihydro-6H-c...)
Affinity DataIC50:  27nMAssay Description:Compounds of general formulas 1 and 2 were tested for their ability to prevent 5-HT6 receptors activation by serotonin. HEK 293 cells (cells of human...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM50314762(5-methyl-2-(methylthio)-3-(phenylsulfonyl)-6,7,8,9...)
Affinity DataIC50:  32nMAssay Description:Compounds of general formulas 1 and 2 were tested for their ability to prevent 5-HT6 receptors activation by serotonin. HEK 293 cells (cells of human...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM50314760(2-(methylthio)-3-(phenylsulfonyl)-6,7,8,9-tetrahyd...)
Affinity DataIC50:  35nMAssay Description:Compounds of general formulas 1 and 2 were tested for their ability to prevent 5-HT6 receptors activation by serotonin. HEK 293 cells (cells of human...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM50314761(2-Methylsulfanyl-3-phenylsulfonyl-5,6,7,8-tetrahyd...)
Affinity DataIC50:  479nMAssay Description:Compounds of general formulas 1 and 2 were tested for their ability to prevent 5-HT6 receptors activation by serotonin. HEK 293 cells (cells of human...More data for this Ligand-Target Pair
In DepthDetails US Patent