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Found 37 Enz. Inhib. hit(s) with all data for entry = 6331
TargetG-protein coupled receptor 4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM123511(US8748435, 36)
Affinity DataIC50:  5nMpH: 8.0Assay Description:Serial dilutions of compounds (stock in 10 mM DMSO) are prepared by first diluting the compounds in DMSO followed by a 1:50 dilution into assay buffe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetG-protein coupled receptor 4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM123488(US8748435, 13)
Affinity DataIC50:  7nMpH: 8.0Assay Description:Serial dilutions of compounds (stock in 10 mM DMSO) are prepared by first diluting the compounds in DMSO followed by a 1:50 dilution into assay buffe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetG-protein coupled receptor 4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM123489(US8748435, 14)
Affinity DataIC50:  10nMpH: 8.0Assay Description:Serial dilutions of compounds (stock in 10 mM DMSO) are prepared by first diluting the compounds in DMSO followed by a 1:50 dilution into assay buffe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetG-protein coupled receptor 4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM123514(US8748435, 39)
Affinity DataIC50:  13nMpH: 8.0Assay Description:Serial dilutions of compounds (stock in 10 mM DMSO) are prepared by first diluting the compounds in DMSO followed by a 1:50 dilution into assay buffe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetG-protein coupled receptor 4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM123513(US8748435, 38)
Affinity DataIC50:  15nMpH: 8.0Assay Description:Serial dilutions of compounds (stock in 10 mM DMSO) are prepared by first diluting the compounds in DMSO followed by a 1:50 dilution into assay buffe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetG-protein coupled receptor 4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM123480(US8748435, 5)
Affinity DataIC50:  15nMpH: 8.0Assay Description:Serial dilutions of compounds (stock in 10 mM DMSO) are prepared by first diluting the compounds in DMSO followed by a 1:50 dilution into assay buffe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetG-protein coupled receptor 4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM123497(US8748435, 22)
Affinity DataIC50:  19nMpH: 8.0Assay Description:Serial dilutions of compounds (stock in 10 mM DMSO) are prepared by first diluting the compounds in DMSO followed by a 1:50 dilution into assay buffe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetG-protein coupled receptor 4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM123484(US8748435, 9)
Affinity DataIC50:  19nMpH: 8.0Assay Description:Serial dilutions of compounds (stock in 10 mM DMSO) are prepared by first diluting the compounds in DMSO followed by a 1:50 dilution into assay buffe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetG-protein coupled receptor 4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM123504(US8748435, 29)
Affinity DataIC50:  21nMpH: 8.0Assay Description:Serial dilutions of compounds (stock in 10 mM DMSO) are prepared by first diluting the compounds in DMSO followed by a 1:50 dilution into assay buffe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetG-protein coupled receptor 4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM123496(US8748435, 21)
Affinity DataIC50:  22nMpH: 8.0Assay Description:Serial dilutions of compounds (stock in 10 mM DMSO) are prepared by first diluting the compounds in DMSO followed by a 1:50 dilution into assay buffe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetG-protein coupled receptor 4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM123481(US8748435, 6)
Affinity DataIC50:  24nMpH: 8.0Assay Description:Serial dilutions of compounds (stock in 10 mM DMSO) are prepared by first diluting the compounds in DMSO followed by a 1:50 dilution into assay buffe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetG-protein coupled receptor 4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM123505(US8748435, 30)
Affinity DataIC50:  26nMpH: 8.0Assay Description:Serial dilutions of compounds (stock in 10 mM DMSO) are prepared by first diluting the compounds in DMSO followed by a 1:50 dilution into assay buffe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetG-protein coupled receptor 4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM123483(US8748435, 8)
Affinity DataIC50:  28nMpH: 8.0Assay Description:Serial dilutions of compounds (stock in 10 mM DMSO) are prepared by first diluting the compounds in DMSO followed by a 1:50 dilution into assay buffe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetG-protein coupled receptor 4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM123492(US8748435, 17)
Affinity DataIC50:  30nMpH: 8.0Assay Description:Serial dilutions of compounds (stock in 10 mM DMSO) are prepared by first diluting the compounds in DMSO followed by a 1:50 dilution into assay buffe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetG-protein coupled receptor 4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM123485(US8748435, 10)
Affinity DataIC50:  33nMpH: 8.0Assay Description:Serial dilutions of compounds (stock in 10 mM DMSO) are prepared by first diluting the compounds in DMSO followed by a 1:50 dilution into assay buffe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetG-protein coupled receptor 4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM123487(US8748435, 12)
Affinity DataIC50:  33nMpH: 8.0Assay Description:Serial dilutions of compounds (stock in 10 mM DMSO) are prepared by first diluting the compounds in DMSO followed by a 1:50 dilution into assay buffe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG-protein coupled receptor 4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM123482(US8748435, 7)
Affinity DataIC50:  34nMpH: 8.0Assay Description:Serial dilutions of compounds (stock in 10 mM DMSO) are prepared by first diluting the compounds in DMSO followed by a 1:50 dilution into assay buffe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetG-protein coupled receptor 4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM123477(US8748435, 2)
Affinity DataIC50:  34nMpH: 8.0Assay Description:Serial dilutions of compounds (stock in 10 mM DMSO) are prepared by first diluting the compounds in DMSO followed by a 1:50 dilution into assay buffe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetG-protein coupled receptor 4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM123498(US8748435, 23)
Affinity DataIC50:  35nMpH: 8.0Assay Description:Serial dilutions of compounds (stock in 10 mM DMSO) are prepared by first diluting the compounds in DMSO followed by a 1:50 dilution into assay buffe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetG-protein coupled receptor 4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM123491(US8748435, 16)
Affinity DataIC50:  35nMpH: 8.0Assay Description:Serial dilutions of compounds (stock in 10 mM DMSO) are prepared by first diluting the compounds in DMSO followed by a 1:50 dilution into assay buffe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetG-protein coupled receptor 4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM123486(US8748435, 11)
Affinity DataIC50:  38nMpH: 8.0Assay Description:Serial dilutions of compounds (stock in 10 mM DMSO) are prepared by first diluting the compounds in DMSO followed by a 1:50 dilution into assay buffe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetG-protein coupled receptor 4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM123508(US8748435, 33)
Affinity DataIC50:  38nMpH: 8.0Assay Description:Serial dilutions of compounds (stock in 10 mM DMSO) are prepared by first diluting the compounds in DMSO followed by a 1:50 dilution into assay buffe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG-protein coupled receptor 4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM123506(US8748435, 31)
Affinity DataIC50:  43nMpH: 8.0Assay Description:Serial dilutions of compounds (stock in 10 mM DMSO) are prepared by first diluting the compounds in DMSO followed by a 1:50 dilution into assay buffe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetG-protein coupled receptor 4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM123501(US8748435, 26)
Affinity DataIC50:  44nMpH: 8.0Assay Description:Serial dilutions of compounds (stock in 10 mM DMSO) are prepared by first diluting the compounds in DMSO followed by a 1:50 dilution into assay buffe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetG-protein coupled receptor 4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM123478(US8748435, 3)
Affinity DataIC50:  44nMpH: 8.0Assay Description:Serial dilutions of compounds (stock in 10 mM DMSO) are prepared by first diluting the compounds in DMSO followed by a 1:50 dilution into assay buffe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetG-protein coupled receptor 4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM123476(US8748435, 1)
Affinity DataIC50:  45nMpH: 8.0Assay Description:Serial dilutions of compounds (stock in 10 mM DMSO) are prepared by first diluting the compounds in DMSO followed by a 1:50 dilution into assay buffe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetG-protein coupled receptor 4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM123479(US8748435, 4)
Affinity DataIC50:  47nMpH: 8.0Assay Description:Serial dilutions of compounds (stock in 10 mM DMSO) are prepared by first diluting the compounds in DMSO followed by a 1:50 dilution into assay buffe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG-protein coupled receptor 4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM123490(US8748435, 15)
Affinity DataIC50:  51nMpH: 8.0Assay Description:Serial dilutions of compounds (stock in 10 mM DMSO) are prepared by first diluting the compounds in DMSO followed by a 1:50 dilution into assay buffe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetG-protein coupled receptor 4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM123499(US8748435, 24)
Affinity DataIC50:  54nMpH: 8.0Assay Description:Serial dilutions of compounds (stock in 10 mM DMSO) are prepared by first diluting the compounds in DMSO followed by a 1:50 dilution into assay buffe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetG-protein coupled receptor 4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM123494(US8748435, 19)
Affinity DataIC50:  54nMpH: 8.0Assay Description:Serial dilutions of compounds (stock in 10 mM DMSO) are prepared by first diluting the compounds in DMSO followed by a 1:50 dilution into assay buffe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG-protein coupled receptor 4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM123515(US8748435, 40)
Affinity DataIC50:  55nMpH: 8.0Assay Description:Serial dilutions of compounds (stock in 10 mM DMSO) are prepared by first diluting the compounds in DMSO followed by a 1:50 dilution into assay buffe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetG-protein coupled receptor 4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM123502(US8748435, 27)
Affinity DataIC50:  59nMpH: 8.0Assay Description:Serial dilutions of compounds (stock in 10 mM DMSO) are prepared by first diluting the compounds in DMSO followed by a 1:50 dilution into assay buffe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetG-protein coupled receptor 4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM123510(US8748435, 35)
Affinity DataIC50:  74nMpH: 8.0Assay Description:Serial dilutions of compounds (stock in 10 mM DMSO) are prepared by first diluting the compounds in DMSO followed by a 1:50 dilution into assay buffe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetG-protein coupled receptor 4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM123509(US8748435, 34)
Affinity DataIC50:  77nMpH: 8.0Assay Description:Serial dilutions of compounds (stock in 10 mM DMSO) are prepared by first diluting the compounds in DMSO followed by a 1:50 dilution into assay buffe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG-protein coupled receptor 4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM123493(US8748435, 18)
Affinity DataIC50:  81nMpH: 8.0Assay Description:Serial dilutions of compounds (stock in 10 mM DMSO) are prepared by first diluting the compounds in DMSO followed by a 1:50 dilution into assay buffe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetG-protein coupled receptor 4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM123500(US8748435, 25)
Affinity DataIC50:  110nMpH: 8.0Assay Description:Serial dilutions of compounds (stock in 10 mM DMSO) are prepared by first diluting the compounds in DMSO followed by a 1:50 dilution into assay buffe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetG-protein coupled receptor 4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM123503(US8748435, 28)
Affinity DataIC50:  118nMpH: 8.0Assay Description:Serial dilutions of compounds (stock in 10 mM DMSO) are prepared by first diluting the compounds in DMSO followed by a 1:50 dilution into assay buffe...More data for this Ligand-Target Pair
In DepthDetails US Patent