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Found 39 Enz. Inhib. hit(s) with all data for entry = 6346
TargetD(3) dopamine receptor(Homo sapiens (Human))
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services

US Patent
LigandPNGBDBM50378001(CHEMBL1627321 | US8748608, 36)
Affinity DataKi:  0.260nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services

US Patent
LigandPNGBDBM50378018(CHEMBL1627322 | US8748608, 37)
Affinity DataKi:  0.5nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services

US Patent
LigandPNGBDBM123847(US8748608, 21)
Affinity DataKi:  0.5nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services

US Patent
LigandPNGBDBM50219117(CHEMBL244562 | N-(4-(4-(2,3-dichlorophenyl)piperaz...)
Affinity DataKi:  0.600nM IC50:  1nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services

US Patent
LigandPNGBDBM123854(US8748608, 47)
Affinity DataKi:  0.650nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services

US Patent
LigandPNGBDBM123850(US8748608, 34 | US8748608, 34 Enantiomer A | US874...)
Affinity DataKi:  0.900nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services

US Patent
LigandPNGBDBM50378006(CHEMBL1627316 | US8748608, 42)
Affinity DataKi:  0.980nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services

US Patent
LigandPNGBDBM123856(US8748608, 49)
Affinity DataKi:  1nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services

US Patent
LigandPNGBDBM123840(US8748608, 12)
Affinity DataKi:  1.10nM IC50:  1.20nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services

US Patent
LigandPNGBDBM123850(US8748608, 34 | US8748608, 34 Enantiomer A | US874...)
Affinity DataKi:  1.10nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services

US Patent
LigandPNGBDBM123849(US8748608, 23)
Affinity DataKi:  1.30nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services

US Patent
LigandPNGBDBM123855(US8748608, 48)
Affinity DataKi:  1.30nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services

US Patent
LigandPNGBDBM50378014(CHEMBL1627308 | US8748608, 35)
Affinity DataKi:  1.37nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services

US Patent
LigandPNGBDBM50219102(CHEMBL398175 | N-(4-(4-(2,3-dichlorophenyl)piperaz...)
Affinity DataKi:  1.40nM IC50:  6.70nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services

US Patent
LigandPNGBDBM50219114(CHEMBL244773 | N-(4-(4-(2,3-dichlorophenyl)piperaz...)
Affinity DataKi:  1.60nM IC50:  25.6nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services

US Patent
LigandPNGBDBM123853(US8748608, 46)
Affinity DataKi:  1.60nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services

US Patent
LigandPNGBDBM123845(US8748608, 19)
Affinity DataKi:  1.80nM IC50:  3.90nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services

US Patent
LigandPNGBDBM123843(US8748608, 17)
Affinity DataKi:  1.80nM IC50:  42nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services

US Patent
LigandPNGBDBM50378003(CHEMBL1627319 | US8748608, 44)
Affinity DataKi:  2.20nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services

US Patent
LigandPNGBDBM123848(US8748608, 22)
Affinity DataKi:  2.5nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services

US Patent
LigandPNGBDBM123844(US8748608, 18)
Affinity DataKi:  2.80nM IC50:  12.8nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services

US Patent
LigandPNGBDBM50219107(CHEMBL394541 | N-(4-(4-(2-methoxyphenyl)piperazin-...)
Affinity DataKi:  2.90nM IC50:  42.6nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services

US Patent
LigandPNGBDBM123842(US8748608, 16)
Affinity DataKi:  3nM IC50:  1nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services

US Patent
LigandPNGBDBM50378004(CHEMBL1627318 | US8748608, 45)
Affinity DataKi:  3.5nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services

US Patent
LigandPNGBDBM50378002(CHEMBL1627320 | US8748608, 39)
Affinity DataKi:  4.60nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services

US Patent
LigandPNGBDBM50378005(CHEMBL1627317 | US8748608, 43)
Affinity DataKi:  5.40nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services

US Patent
LigandPNGBDBM123846(US8748608, 20)
Affinity DataKi:  11.7nM IC50:  5.40nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services

US Patent
LigandPNGBDBM50219113(CHEMBL244989 | N-(4-(4-(2-methoxyphenyl)piperazin-...)
Affinity DataKi:  12nM IC50:  18.9nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services

US Patent
LigandPNGBDBM123850(US8748608, 34 | US8748608, 34 Enantiomer A | US874...)
Affinity DataKi:  16.5nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services

US Patent
LigandPNGBDBM123841(US8748608, 13)
Affinity DataKi:  49.2nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services

US Patent
LigandPNGBDBM50378013(CHEMBL1627309 | US8748608, 38)
Affinity DataKi:  62.1nMAssay Description:Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services

US Patent
LigandPNGBDBM123842(US8748608, 16)
Affinity DataIC50:  15.8nMT: 2°CAssay Description:To measure D2 and D3 stimulation of mitogenesis (agonist assay) or D2 and D3 inhibition of quinpirole stimulation of mitogenesis (antagonist assay), ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services

US Patent
LigandPNGBDBM123840(US8748608, 12)
Affinity DataIC50:  22.9nMT: 2°CAssay Description:To measure D2 and D3 stimulation of mitogenesis (agonist assay) or D2 and D3 inhibition of quinpirole stimulation of mitogenesis (antagonist assay), ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services

US Patent
LigandPNGBDBM50219117(CHEMBL244562 | N-(4-(4-(2,3-dichlorophenyl)piperaz...)
Affinity DataIC50:  41nMT: 2°CAssay Description:To measure D2 and D3 stimulation of mitogenesis (agonist assay) or D2 and D3 inhibition of quinpirole stimulation of mitogenesis (antagonist assay), ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services

US Patent
LigandPNGBDBM123847(US8748608, 21)
Affinity DataIC50:  88.3nMT: 2°CAssay Description:To measure D2 and D3 stimulation of mitogenesis (agonist assay) or D2 and D3 inhibition of quinpirole stimulation of mitogenesis (antagonist assay), ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services

US Patent
LigandPNGBDBM50219107(CHEMBL394541 | N-(4-(4-(2-methoxyphenyl)piperazin-...)
Affinity DataIC50:  175nMT: 2°CAssay Description:To measure D2 and D3 stimulation of mitogenesis (agonist assay) or D2 and D3 inhibition of quinpirole stimulation of mitogenesis (antagonist assay), ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services

US Patent
LigandPNGBDBM50219113(CHEMBL244989 | N-(4-(4-(2-methoxyphenyl)piperazin-...)
Affinity DataIC50:  179nMT: 2°CAssay Description:To measure D2 and D3 stimulation of mitogenesis (agonist assay) or D2 and D3 inhibition of quinpirole stimulation of mitogenesis (antagonist assay), ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services

US Patent
LigandPNGBDBM50219114(CHEMBL244773 | N-(4-(4-(2,3-dichlorophenyl)piperaz...)
Affinity DataIC50:  368nMT: 2°CAssay Description:To measure D2 and D3 stimulation of mitogenesis (agonist assay) or D2 and D3 inhibition of quinpirole stimulation of mitogenesis (antagonist assay), ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services

US Patent
LigandPNGBDBM50219102(CHEMBL398175 | N-(4-(4-(2,3-dichlorophenyl)piperaz...)
Affinity DataIC50:  1.30E+3nMT: 2°CAssay Description:To measure D2 and D3 stimulation of mitogenesis (agonist assay) or D2 and D3 inhibition of quinpirole stimulation of mitogenesis (antagonist assay), ...More data for this Ligand-Target Pair
In DepthDetails US Patent