Compile Data Set for Download or QSAR
maximum 50k data
Found 8 Enz. Inhib. hit(s) with all data for entry = 6330
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM123468(US8748626, 1)
Affinity DataIC50:  0.840nMpH: 7.5 T: 2°CAssay Description:This example provides a representative in vitro assay for determining KSP activity in vitro. Purified microtubules obtained from bovine brain were pu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM123472(US8748626, 5)
Affinity DataIC50:  2.54nMpH: 7.5 T: 2°CAssay Description:This example provides a representative in vitro assay for determining KSP activity in vitro. Purified microtubules obtained from bovine brain were pu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM123470(US8748626, 3)
Affinity DataIC50:  2.60nMpH: 7.5 T: 2°CAssay Description:This example provides a representative in vitro assay for determining KSP activity in vitro. Purified microtubules obtained from bovine brain were pu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM123471(US8748626, 4)
Affinity DataIC50:  7.18nMpH: 7.5 T: 2°CAssay Description:This example provides a representative in vitro assay for determining KSP activity in vitro. Purified microtubules obtained from bovine brain were pu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM123469(US8748626, 2)
Affinity DataIC50:  10nMpH: 7.5 T: 2°CAssay Description:This example provides a representative in vitro assay for determining KSP activity in vitro. Purified microtubules obtained from bovine brain were pu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM123475(US8748626, 8)
Affinity DataIC50:  216nMpH: 7.5 T: 2°CAssay Description:This example provides a representative in vitro assay for determining KSP activity in vitro. Purified microtubules obtained from bovine brain were pu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM123474(US8748626, 7)
Affinity DataIC50:  631nMpH: 7.5 T: 2°CAssay Description:This example provides a representative in vitro assay for determining KSP activity in vitro. Purified microtubules obtained from bovine brain were pu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM123473(US8748626, 6)
Affinity DataIC50:  1.00E+3nMpH: 7.5 T: 2°CAssay Description:This example provides a representative in vitro assay for determining KSP activity in vitro. Purified microtubules obtained from bovine brain were pu...More data for this Ligand-Target Pair
In DepthDetails US Patent