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Found 162 Enz. Inhib. hit(s) with all data for entry = 6366
LigandPNGBDBM50403100(CHEMBL2216891 | US8765940, 4-(3,3-dimethyl-6-(4-mo...)
Affinity DataKi:  1.05nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM124797(US8765940, 1-(5,7-difluoro-3-methyl-4-(6'-(4-morph...)
Affinity DataKi:  1.27nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM124781(US8765940, 1-(7-fluoro-3-methyl-2-(2-pyridinyl)-4-...)
Affinity DataKi:  1.37nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
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LigandPNGBDBM124778(US8765940, 1-(5,7-difluoro-3-methyl-4-(6'-(4-m...)
Affinity DataKi:  1.49nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
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LigandPNGBDBM124765(US8765940, 1'-(5,7-difluoro-3-methyl-2-(5-meth...)
Affinity DataKi:  1.51nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
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LigandPNGBDBM124764(US8765940, 2-(2,2-dimethyl-4-morpholinyl)-4-(3,3-d...)
Affinity DataKi:  1.52nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
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LigandPNGBDBM124749(US8765940, 1-(4-(3,3-dimethyl-6-(4-morpholinyl)-2,...)
Affinity DataKi:  1.54nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
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LigandPNGBDBM124759(US8765940, 1-(7-fluoro-3-methyl-4-(6'-(4-morph...)
Affinity DataKi:  1.62nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
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LigandPNGBDBM124767(US8765940, 1-(7-fluoro-3-methyl-2-(4-methyl-2-pyri...)
Affinity DataKi:  1.96nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
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LigandPNGBDBM124766(US8765940, 1-(7-fluoro-3-methyl-2-(2-pyridinyl)-4-...)
Affinity DataKi:  2.22nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
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LigandPNGBDBM124799(US8765940, 4-(3,3-dimethyl-6-(4-morpholinyl)-2,3-d...)
Affinity DataKi:  2.24nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
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LigandPNGBDBM124783(US8765940, 4-(3,3-dimethyl-6-(4-morpholinyl)-2,3-d...)
Affinity DataKi:  2.30nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
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LigandPNGBDBM124798(US8765940, 1-(5,7-difluoro-3-methyl-4-(6'-(4-morph...)
Affinity DataKi:  2.30nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
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LigandPNGBDBM124743(US8765940, 4-(3,3-dimethyl-6-(4-morpholinyl)-2,3-d...)
Affinity DataKi:  2.34nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
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LigandPNGBDBM124775(US8765940, 4-(3,3-dimethyl-6-(4-morpholinyl)-2,3-d...)
Affinity DataKi:  2.36nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
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LigandPNGBDBM124758(US8765940, 1-(5,7-difluoro-3-methyl-4-(6'-(4-morph...)
Affinity DataKi:  2.36nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
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LigandPNGBDBM124676(US8765940, 4-(1-(7-fluoro-3-methyl-2-(2-(methylsul...)
Affinity DataKi:  2.44nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
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LigandPNGBDBM124734(US8765940, 3-((4-(3,3-dimethyl-6-(4-morpholinyl)-2...)
Affinity DataKi:  2.68nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
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LigandPNGBDBM124757(US8765940, 1'-(8-chloro-2,3-dimethyl-4-quinoli...)
Affinity DataKi:  2.68nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
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LigandPNGBDBM124779(US8765940, tert-butyl 4-(5,7-difluoro-3-methyl-4-(...)
Affinity DataKi:  2.70nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
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LigandPNGBDBM124731(US8765940, 4-(3,3-dimethyl-6-(4-morpholinyl)-2,3-d...)
Affinity DataKi:  2.77nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
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LigandPNGBDBM124732(US8765940, 4-(3,3-dimethyl-6-(4-morpholinyl)-2,3-d...)
Affinity DataKi:  2.87nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
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LigandPNGBDBM124728(US8765940, 4-(3,3-dimethyl-6-(4-morpholinyl)-2,3-d...)
Affinity DataKi:  2.90nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
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LigandPNGBDBM124747(US8765940, 4-(3,3-dimethyl-6-(4-morpholinyl)-2,3-d...)
Affinity DataKi:  3nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
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LigandPNGBDBM124777(US8765940, methyl 4-(5,7-difluoro-3-methyl-4-(6...)
Affinity DataKi:  3.11nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
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LigandPNGBDBM124742(US8765940, 1-(4-(3,3-dimethyl-6-(4-morpholinyl)-2,...)
Affinity DataKi:  3.14nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
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LigandPNGBDBM124796(US8765940, 4-(5,7-difluoro-3-methyl-4-(6'-(4-morph...)
Affinity DataKi:  3.16nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
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LigandPNGBDBM124727(US8765940, 2-benzyl-4-(3,3-dimethyl-6-(4-morpholin...)
Affinity DataKi:  3.20nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
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LigandPNGBDBM50396616(CHEMBL2171930 | US8765940, 4-(1-(7-fluoro-3-methyl...)
Affinity DataKi:  3.32nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
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LigandPNGBDBM124683(US8765940, 4-(3,3-dimethyl-6-(4-morpholinyl)-2,3-d...)
Affinity DataKi:  3.33nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
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LigandPNGBDBM124667(US8765940, 4-(3,3-dimethyl-6-(4-morpholinyl)-2,3-d...)
Affinity DataKi:  4.07nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
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LigandPNGBDBM124688(US8765940, 4-(3,3-dimethyl-6-(4-morpholinyl)-2,3-d...)
Affinity DataKi:  4.07nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
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LigandPNGBDBM124741(US8765940, 4-(3,3-dimethyl-6-(4-morpholinyl)-2,3-d...)
Affinity DataKi:  4.17nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
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LigandPNGBDBM124786(US8765940, 1'-(3-methyl-2-phenyl-1,8-naphthyri...)
Affinity DataKi:  4.36nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
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LigandPNGBDBM124675(US8765940, 4-(3,3-dimethyl-6-(4-morpholinyl)-2,3-d...)
Affinity DataKi:  4.43nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
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LigandPNGBDBM124755(US8765940, 1'-(5,7-difluoro-3-methyl-2-(2-(met...)
Affinity DataKi:  4.51nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
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LigandPNGBDBM124756(US8765940, 1-(5,7-difluoro-3-methyl-4-(6-(4-morpho...)
Affinity DataKi:  4.64nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM124761(US8765940, 1'-(7-fluoro-3-methyl-2-(4-methyl-2...)
Affinity DataKi:  5.19nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
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LigandPNGBDBM124746(US8765940, 4-(3,3-dimethyl-6-(4-morpholinyl)-2,3-d...)
Affinity DataKi:  5.21nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
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LigandPNGBDBM124801(US8765940, 4-(3,3-dimethyl-6-(4-morpholinyl)-2,3-d...)
Affinity DataKi:  5.37nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
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LigandPNGBDBM124784(US8765940, 1'-(2-(3-fluorophenyl)-3-methyl-1,8...)
Affinity DataKi:  5.38nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
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LigandPNGBDBM124763(US8765940, 1'-(2-(2,2-dimethyl-4-morpholinyl)-...)
Affinity DataKi:  5.40nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
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LigandPNGBDBM124751(US8765940, 1-(5,7-difluoro-3-methyl-4-(6'-(4-m...)
Affinity DataKi:  5.51nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
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LigandPNGBDBM124665(US8765940, 4-(3,3-dimethyl-6-(4-morpholinyl)-2,3-d...)
Affinity DataKi:  5.87nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
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LigandPNGBDBM124736(US8765940, 4-(6-(3,6-dihydro-2H-pyran-4-yl)-3,3-di...)
Affinity DataKi:  6.47nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM124753(US8765940, 1'-(5-fluoro-3-methyl-2-(2-pyridiny...)
Affinity DataKi:  6.48nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
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LigandPNGBDBM50396610(CHEMBL2171929 | US8765940, 4-(3,3-dimethyl-6-(4-mo...)
Affinity DataKi:  6.76nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
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LigandPNGBDBM124762(US8765940, 1'-(5,7-difluoro-2-(2-methoxy-4-pyr...)
Affinity DataKi:  6.89nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
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LigandPNGBDBM124769(US8765940, 1-(7-fluoro-3-methyl-4-(6'-(4-morpholin...)
Affinity DataKi:  7.64nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
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LigandPNGBDBM50396613(CHEMBL2171924 | US8765940, 1-(7-fluoro-3-methyl-2-...)
Affinity DataKi:  7.75nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
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