Compile Data Set for Download or QSAR
maximum 50k data
Found 24 Enz. Inhib. hit(s) with all data for entry = 6666
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Canada

US Patent
LigandPNGBDBM144433(US8969394, 5)
Affinity DataKi:  0.470nM ΔG°:  -53.2kJ/molepH: 6.0 T: 2°CAssay Description:Transfected HEK 293(ebna) cells are maintained in culture, harvested and membranes are prepared by differential centrifugation, following lysis of th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Canada

US Patent
LigandPNGBDBM50308131(4-{1-[({2,5-Dimethyl-4-[4-(trifluoromethyl)benzyl]...)
Affinity DataKi:  0.5nM ΔG°:  -53.1kJ/molepH: 6.0 T: 2°CAssay Description:Transfected HEK 293(ebna) cells are maintained in culture, harvested and membranes are prepared by differential centrifugation, following lysis of th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Canada

US Patent
LigandPNGBDBM144440(US8969394, 14)
Affinity DataKi:  0.600nM ΔG°:  -52.6kJ/molepH: 6.0 T: 2°CAssay Description:Transfected HEK 293(ebna) cells are maintained in culture, harvested and membranes are prepared by differential centrifugation, following lysis of th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Canada

US Patent
LigandPNGBDBM144447(US8969394, 26)
Affinity DataKi:  0.700nM ΔG°:  -52.3kJ/molepH: 6.0 T: 2°CAssay Description:Transfected HEK 293(ebna) cells are maintained in culture, harvested and membranes are prepared by differential centrifugation, following lysis of th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Canada

US Patent
LigandPNGBDBM144432(US8969394, 4)
Affinity DataKi:  0.710nM ΔG°:  -52.2kJ/molepH: 6.0 T: 2°CAssay Description:Transfected HEK 293(ebna) cells are maintained in culture, harvested and membranes are prepared by differential centrifugation, following lysis of th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Canada

US Patent
LigandPNGBDBM50308130(4-{1-[({2,5-Dimethyl-4-[3-(trifluoromethyl)benzyl]...)
Affinity DataKi:  0.800nM ΔG°:  -51.9kJ/molepH: 6.0 T: 2°CAssay Description:Transfected HEK 293(ebna) cells are maintained in culture, harvested and membranes are prepared by differential centrifugation, following lysis of th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Canada

US Patent
LigandPNGBDBM144445(US8969394, 21)
Affinity DataKi:  0.800nM ΔG°:  -51.9kJ/molepH: 6.0 T: 2°CAssay Description:Transfected HEK 293(ebna) cells are maintained in culture, harvested and membranes are prepared by differential centrifugation, following lysis of th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Canada

US Patent
LigandPNGBDBM50308134(4-[({[2,5-Dichloro-4-(3-chlorobenzyl)-3-thienyl]ca...)
Affinity DataKi:  0.900nM ΔG°:  -51.6kJ/molepH: 6.0 T: 2°CAssay Description:Transfected HEK 293(ebna) cells are maintained in culture, harvested and membranes are prepared by differential centrifugation, following lysis of th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Canada

US Patent
LigandPNGBDBM50308133(4-[(1R)-1-({[2,5-Dichloro-4-(3-chlorobenzyl)-3-thi...)
Affinity DataKi:  0.900nM ΔG°:  -51.6kJ/molepH: 6.0 T: 2°CAssay Description:Transfected HEK 293(ebna) cells are maintained in culture, harvested and membranes are prepared by differential centrifugation, following lysis of th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Canada

US Patent
LigandPNGBDBM50308125(4-[(1S)-1-({[2,5-Dichloro-4-(3-chlorobenzyl)-3-thi...)
Affinity DataKi:  1.30nM ΔG°:  -50.7kJ/molepH: 6.0 T: 2°CAssay Description:Transfected HEK 293(ebna) cells are maintained in culture, harvested and membranes are prepared by differential centrifugation, following lysis of th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Canada

US Patent
LigandPNGBDBM50308129(4-{(1S)-1-[({2,5-Dimethyl-4-[4-(trifluoromethyl)be...)
Affinity DataKi:  1.40nM ΔG°:  -50.5kJ/molepH: 6.0 T: 2°CAssay Description:Transfected HEK 293(ebna) cells are maintained in culture, harvested and membranes are prepared by differential centrifugation, following lysis of th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Canada

US Patent
LigandPNGBDBM144436(US8969394, 9)
Affinity DataKi:  1.80nM ΔG°:  -49.9kJ/molepH: 6.0 T: 2°CAssay Description:Transfected HEK 293(ebna) cells are maintained in culture, harvested and membranes are prepared by differential centrifugation, following lysis of th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Canada

US Patent
LigandPNGBDBM50308127(4-{(1S)-1-[({2,5-Dimethyl-4-[3-(trifluoromethyl)be...)
Affinity DataKi:  2.40nM ΔG°:  -49.2kJ/molepH: 6.0 T: 2°CAssay Description:Transfected HEK 293(ebna) cells are maintained in culture, harvested and membranes are prepared by differential centrifugation, following lysis of th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Canada

US Patent
LigandPNGBDBM144431(US8969394, 2)
Affinity DataKi:  2.60nM ΔG°:  -49.0kJ/molepH: 6.0 T: 2°CAssay Description:Transfected HEK 293(ebna) cells are maintained in culture, harvested and membranes are prepared by differential centrifugation, following lysis of th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Canada

US Patent
LigandPNGBDBM50308126(4-[(1S)-1-({[4-(3-Chlorobenzyl)-2,5-dimethyl-3-thi...)
Affinity DataKi:  3.10nM ΔG°:  -48.6kJ/molepH: 6.0 T: 2°CAssay Description:Transfected HEK 293(ebna) cells are maintained in culture, harvested and membranes are prepared by differential centrifugation, following lysis of th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Canada

US Patent
LigandPNGBDBM50308128(4-[(1S)-1-({[4-(4-Chlorobenzyl)-2,5-dimethyl-3-thi...)
Affinity DataKi:  3.40nM ΔG°:  -48.3kJ/molepH: 6.0 T: 2°CAssay Description:Transfected HEK 293(ebna) cells are maintained in culture, harvested and membranes are prepared by differential centrifugation, following lysis of th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Canada

US Patent
LigandPNGBDBM144430(US8969394, 1)
Affinity DataKi:  5.20nM ΔG°:  -47.3kJ/molepH: 6.0 T: 2°CAssay Description:Transfected HEK 293(ebna) cells are maintained in culture, harvested and membranes are prepared by differential centrifugation, following lysis of th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Canada

US Patent
LigandPNGBDBM144437(US8969394, 10)
Affinity DataKi:  7.40nM ΔG°:  -46.4kJ/molepH: 6.0 T: 2°CAssay Description:Transfected HEK 293(ebna) cells are maintained in culture, harvested and membranes are prepared by differential centrifugation, following lysis of th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Canada

US Patent
LigandPNGBDBM50308124(4-[(1S)-1-({[4-(3-Chlorobenzyl)-3-thienyl]carbonyl...)
Affinity DataKi:  7.90nM ΔG°:  -46.2kJ/molepH: 6.0 T: 2°CAssay Description:Transfected HEK 293(ebna) cells are maintained in culture, harvested and membranes are prepared by differential centrifugation, following lysis of th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Canada

US Patent
LigandPNGBDBM144446(US8969394, 25)
Affinity DataKi:  30nM ΔG°:  -42.9kJ/molepH: 6.0 T: 2°CAssay Description:Transfected HEK 293(ebna) cells are maintained in culture, harvested and membranes are prepared by differential centrifugation, following lysis of th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Canada

US Patent
LigandPNGBDBM144435(US8969394, 8)
Affinity DataKi:  51nM ΔG°:  -41.6kJ/molepH: 6.0 T: 2°CAssay Description:Transfected HEK 293(ebna) cells are maintained in culture, harvested and membranes are prepared by differential centrifugation, following lysis of th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Canada

US Patent
LigandPNGBDBM144434(US8969394, 6)
Affinity DataKi:  124nM ΔG°:  -39.4kJ/molepH: 6.0 T: 2°CAssay Description:Transfected HEK 293(ebna) cells are maintained in culture, harvested and membranes are prepared by differential centrifugation, following lysis of th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Canada

US Patent
LigandPNGBDBM144444(US8969394, 19)
Affinity DataKi:  133nM ΔG°:  -39.2kJ/molepH: 6.0 T: 2°CAssay Description:Transfected HEK 293(ebna) cells are maintained in culture, harvested and membranes are prepared by differential centrifugation, following lysis of th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Canada

US Patent
LigandPNGBDBM144443(US8969394, 18)
Affinity DataKi:  308nM ΔG°:  -37.2kJ/molepH: 6.0 T: 2°CAssay Description:Transfected HEK 293(ebna) cells are maintained in culture, harvested and membranes are prepared by differential centrifugation, following lysis of th...More data for this Ligand-Target Pair
In DepthDetails US Patent