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Found 14 Enz. Inhib. hit(s) with all data for entry = 6732
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM150239(US8980929, Example Compound 7)
Affinity DataIC50:  0.5nMpH: 7.5Assay Description:A continuous fluorometric assay is employed with the substrate Gly-Pro-AMC, which is cleaved by DPP-4 to release the fluorescent AMC leaving group. T...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM150234(US8980929, Example Compound 2)
Affinity DataIC50:  2.20nMpH: 7.5Assay Description:A continuous fluorometric assay is employed with the substrate Gly-Pro-AMC, which is cleaved by DPP-4 to release the fluorescent AMC leaving group. T...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM150233(US8980929, Example Compound 1)
Affinity DataIC50:  2.30nMpH: 7.5Assay Description:A continuous fluorometric assay is employed with the substrate Gly-Pro-AMC, which is cleaved by DPP-4 to release the fluorescent AMC leaving group. T...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM150237(US8980929, Example Compound 5)
Affinity DataIC50:  2.60nMpH: 7.5Assay Description:A continuous fluorometric assay is employed with the substrate Gly-Pro-AMC, which is cleaved by DPP-4 to release the fluorescent AMC leaving group. T...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM150235(US8980929, Example Compound 3)
Affinity DataIC50:  3nMpH: 7.5Assay Description:A continuous fluorometric assay is employed with the substrate Gly-Pro-AMC, which is cleaved by DPP-4 to release the fluorescent AMC leaving group. T...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM150240(US8980929, Example Compound 14 | US8980929, Exampl...)
Affinity DataIC50:  4nMpH: 7.5Assay Description:A continuous fluorometric assay is employed with the substrate Gly-Pro-AMC, which is cleaved by DPP-4 to release the fluorescent AMC leaving group. T...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM150241(US8980929, Example Compound 9)
Affinity DataIC50:  4.10nMpH: 7.5Assay Description:A continuous fluorometric assay is employed with the substrate Gly-Pro-AMC, which is cleaved by DPP-4 to release the fluorescent AMC leaving group. T...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM150238(US8980929, Example Compound 6)
Affinity DataIC50:  5.80nMpH: 7.5Assay Description:A continuous fluorometric assay is employed with the substrate Gly-Pro-AMC, which is cleaved by DPP-4 to release the fluorescent AMC leaving group. T...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM150244(US8980929, Example Compound 12)
Affinity DataIC50:  5.90nMpH: 7.5Assay Description:A continuous fluorometric assay is employed with the substrate Gly-Pro-AMC, which is cleaved by DPP-4 to release the fluorescent AMC leaving group. T...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM150245(US8980929, Example Compound 13)
Affinity DataIC50:  8.10nMpH: 7.5Assay Description:A continuous fluorometric assay is employed with the substrate Gly-Pro-AMC, which is cleaved by DPP-4 to release the fluorescent AMC leaving group. T...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM150236(US8980929, Example Compound 4)
Affinity DataIC50:  8.5nMpH: 7.5Assay Description:A continuous fluorometric assay is employed with the substrate Gly-Pro-AMC, which is cleaved by DPP-4 to release the fluorescent AMC leaving group. T...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM150240(US8980929, Example Compound 14 | US8980929, Exampl...)
Affinity DataIC50:  12.6nMpH: 7.5Assay Description:A continuous fluorometric assay is employed with the substrate Gly-Pro-AMC, which is cleaved by DPP-4 to release the fluorescent AMC leaving group. T...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM150242(US8980929, Example Compound 10)
Affinity DataIC50:  14.3nMpH: 7.5Assay Description:A continuous fluorometric assay is employed with the substrate Gly-Pro-AMC, which is cleaved by DPP-4 to release the fluorescent AMC leaving group. T...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM150243(US8980929, Example Compound 11)
Affinity DataIC50:  21.1nMpH: 7.5Assay Description:A continuous fluorometric assay is employed with the substrate Gly-Pro-AMC, which is cleaved by DPP-4 to release the fluorescent AMC leaving group. T...More data for this Ligand-Target Pair
In DepthDetails US Patent