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Found 26 Enz. Inhib. hit(s) with all data for entry = 6739
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM150313(US8987248, 106)
Affinity DataIC50:  7.05nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM150314(US8987248, 115)
Affinity DataIC50:  11.1nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM150322(US8987248, 156)
Affinity DataIC50:  11.1nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM150319(US8987248, 133)
Affinity DataIC50:  14.6nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM150320(US8987248, 134)
Affinity DataIC50:  15.4nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM150315(US8987248, 119)
Affinity DataIC50:  15.7nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM150317(US8987248, 128)
Affinity DataIC50:  17.0nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM150307(US8987248, 91)
Affinity DataIC50:  17.4nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM150312(US8987248, 105)
Affinity DataIC50:  18.4nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM150305(US8987248, 83)
Affinity DataIC50:  19.7nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM150324(BDBM150325 | US8987248, 170)
Affinity DataIC50:  21.3nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM150323(US8987248, 162)
Affinity DataIC50:  25nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM150301(US8987248, 7)
Affinity DataIC50:  29nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM150318(US8987248, 129)
Affinity DataIC50:  33.6nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM150321(US8987248, 141)
Affinity DataIC50:  53.7nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM150326(US8987248, 178)
Affinity DataIC50:  63nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM150316(US8987248, 121)
Affinity DataIC50:  79.9nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM150324(BDBM150325 | US8987248, 170)
Affinity DataIC50:  81nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM150304(US8987248, 36)
Affinity DataIC50:  98.2nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM150309(US8987248, 97)
Affinity DataIC50:  109nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM150302(US8987248, 8)
Affinity DataIC50:  109nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM150310(US8987248, 102)
Affinity DataIC50:  165nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM150308(US8987248, 95)
Affinity DataIC50:  237nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM150311(US8987248, 104)
Affinity DataIC50:  248nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM150306(US8987248, 90)
Affinity DataIC50:  359nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM150303(US8987248, 18)
Affinity DataIC50:  483nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
In DepthDetails US Patent