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Found 8 Enz. Inhib. hit(s) with all data for entry = 6741
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM150692(US8987254, 7)
Affinity DataIC50:  0.358nMpH: 4.6 T: 2°CAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20x in KH2PO4 buffer. Ten uL of each dilution is ad...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM150690(US8987254, 5)
Affinity DataIC50:  0.450nMpH: 4.6 T: 2°CAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20x in KH2PO4 buffer. Ten uL of each dilution is ad...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM150687(US8987254, 2)
Affinity DataIC50:  0.482nMpH: 4.6 T: 2°CAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20x in KH2PO4 buffer. Ten uL of each dilution is ad...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM150688(US8987254, 3 | US9999624, 3)
Affinity DataIC50:  0.554nMpH: 4.6 T: 2°CAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20x in KH2PO4 buffer. Ten uL of each dilution is ad...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM150689(US8987254, 4)
Affinity DataIC50:  0.569nMpH: 4.6 T: 2°CAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20x in KH2PO4 buffer. Ten uL of each dilution is ad...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM150686(US8987254, 1 | US9999624, 1)
Affinity DataIC50:  0.610nMpH: 4.6 T: 2°CAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20x in KH2PO4 buffer. Ten uL of each dilution is ad...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM150693(US8987254, 8 | US9999624, 9)
Affinity DataIC50:  0.730nMpH: 4.6 T: 2°CAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20x in KH2PO4 buffer. Ten uL of each dilution is ad...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM150691(US8987254, 6 | US9999624, 7)
Affinity DataIC50:  0.739nMpH: 4.6 T: 2°CAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20x in KH2PO4 buffer. Ten uL of each dilution is ad...More data for this Ligand-Target Pair
In DepthDetails US Patent