Compile Data Set for Download or QSAR
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Found 15 Enz. Inhib. hit(s) with all data for entry = 6870
TargetCytochrome P450 2D6(Homo sapiens (Human))
Epizyme

US Patent
LigandPNGBDBM155255(US10098888, Compound 105 | US11642348, Compound 10...)
Affinity DataIC50:  2.95E+3nMpH: 7.4Assay Description:The potential inhibition of enzyme activities of human cytochromes P450 (CYP) of Compound 1, 2, or 105 was evaluated using pooled human liver microso...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2D6(Homo sapiens (Human))
Epizyme

US Patent
LigandPNGBDBM155253(US10098888, Compound 1 | US9006242, 1)
Affinity DataIC50:  2.29E+4nMpH: 7.4Assay Description:The potential inhibition of enzyme activities of human cytochromes P450 (CYP) of Compound 1, 2, or 105 was evaluated using pooled human liver microso...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2C19(Homo sapiens (Human))
Epizyme

US Patent
LigandPNGBDBM155255(US10098888, Compound 105 | US11642348, Compound 10...)
Affinity DataIC50:  3.37E+4nMpH: 7.4Assay Description:The potential inhibition of enzyme activities of human cytochromes P450 (CYP) of Compound 1, 2, or 105 was evaluated using pooled human liver microso...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2C8(Homo sapiens (Human))
Epizyme

US Patent
LigandPNGBDBM155255(US10098888, Compound 105 | US11642348, Compound 10...)
Affinity DataIC50:  4.74E+4nMpH: 7.4Assay Description:The potential inhibition of enzyme activities of human cytochromes P450 (CYP) of Compound 1, 2, or 105 was evaluated using pooled human liver microso...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2C9(Homo sapiens (Human))
Epizyme

US Patent
LigandPNGBDBM155255(US10098888, Compound 105 | US11642348, Compound 10...)
Affinity DataIC50:  7.57E+4nMpH: 7.4Assay Description:The potential inhibition of enzyme activities of human cytochromes P450 (CYP) of Compound 1, 2, or 105 was evaluated using pooled human liver microso...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2C19(Homo sapiens (Human))
Epizyme

US Patent
LigandPNGBDBM155253(US10098888, Compound 1 | US9006242, 1)
Affinity DataIC50:  8.96E+4nMpH: 7.4Assay Description:The potential inhibition of enzyme activities of human cytochromes P450 (CYP) of Compound 1, 2, or 105 was evaluated using pooled human liver microso...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2C19(Homo sapiens (Human))
Epizyme

US Patent
LigandPNGBDBM155254(US10098888, Compound 2 | US9006242, 2)
Affinity DataIC50: >1.00E+5nMpH: 7.4Assay Description:The potential inhibition of enzyme activities of human cytochromes P450 (CYP) of Compound 1, 2, or 105 was evaluated using pooled human liver microso...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2D6(Homo sapiens (Human))
Epizyme

US Patent
LigandPNGBDBM155254(US10098888, Compound 2 | US9006242, 2)
Affinity DataIC50: >1.00E+5nMpH: 7.4Assay Description:The potential inhibition of enzyme activities of human cytochromes P450 (CYP) of Compound 1, 2, or 105 was evaluated using pooled human liver microso...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2C9(Homo sapiens (Human))
Epizyme

US Patent
LigandPNGBDBM155254(US10098888, Compound 2 | US9006242, 2)
Affinity DataIC50: >1.00E+5nMpH: 7.4Assay Description:The potential inhibition of enzyme activities of human cytochromes P450 (CYP) of Compound 1, 2, or 105 was evaluated using pooled human liver microso...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2C9(Homo sapiens (Human))
Epizyme

US Patent
LigandPNGBDBM155253(US10098888, Compound 1 | US9006242, 1)
Affinity DataIC50: >1.00E+5nMpH: 7.4Assay Description:The potential inhibition of enzyme activities of human cytochromes P450 (CYP) of Compound 1, 2, or 105 was evaluated using pooled human liver microso...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2C8(Homo sapiens (Human))
Epizyme

US Patent
LigandPNGBDBM155254(US10098888, Compound 2 | US9006242, 2)
Affinity DataIC50: >1.00E+5nMpH: 7.4Assay Description:The potential inhibition of enzyme activities of human cytochromes P450 (CYP) of Compound 1, 2, or 105 was evaluated using pooled human liver microso...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2C8(Homo sapiens (Human))
Epizyme

US Patent
LigandPNGBDBM155253(US10098888, Compound 1 | US9006242, 1)
Affinity DataIC50: >1.00E+5nMpH: 7.4Assay Description:The potential inhibition of enzyme activities of human cytochromes P450 (CYP) of Compound 1, 2, or 105 was evaluated using pooled human liver microso...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 1A1(Homo sapiens (Human))
Epizyme

US Patent
LigandPNGBDBM155255(US10098888, Compound 105 | US11642348, Compound 10...)
Affinity DataIC50: >1.00E+5nMpH: 7.4Assay Description:The potential inhibition of enzyme activities of human cytochromes P450 (CYP) of Compound 1, 2, or 105 was evaluated using pooled human liver microso...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 1A1(Homo sapiens (Human))
Epizyme

US Patent
LigandPNGBDBM155253(US10098888, Compound 1 | US9006242, 1)
Affinity DataIC50: >1.00E+5nMpH: 7.4Assay Description:The potential inhibition of enzyme activities of human cytochromes P450 (CYP) of Compound 1, 2, or 105 was evaluated using pooled human liver microso...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 1A1(Homo sapiens (Human))
Epizyme

US Patent
LigandPNGBDBM155254(US10098888, Compound 2 | US9006242, 2)
Affinity DataIC50: >1.00E+5nMpH: 7.4Assay Description:The potential inhibition of enzyme activities of human cytochromes P450 (CYP) of Compound 1, 2, or 105 was evaluated using pooled human liver microso...More data for this Ligand-Target Pair
In DepthDetails US Patent