Compile Data Set for Download or QSAR
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Found 243 Enz. Inhib. hit(s) with all data for entry = 7004
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM165905(US9067922, 247)
Affinity DataIC50:  1nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM165898(US9067922, 239)
Affinity DataIC50:  2nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM165900(US9067922, 241)
Affinity DataIC50:  3nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM165745(US9067922, 235 | US9067922, 79)
Affinity DataIC50:  7nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM165896(US9067922, 237)
Affinity DataIC50:  8nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM165893(US9067922, 232)
Affinity DataIC50:  12nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM165667(US9067922, 1)
Affinity DataIC50:  13nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM165745(US9067922, 235 | US9067922, 79)
Affinity DataIC50:  13nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM165769(US9067922, 104)
Affinity DataIC50:  15nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM165744(US9067922, 78)
Affinity DataIC50:  19nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM60431(US9067922, 249)
Affinity DataIC50:  21nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM165780(US9067922, 115)
Affinity DataIC50:  24nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM165736(US9067922, 70)
Affinity DataIC50:  25nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM165728(US9067922, 62)
Affinity DataIC50:  27nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM165737(US9067922, 71)
Affinity DataIC50:  27nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM165764(US9067922, 99)
Affinity DataIC50:  29nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM165863(US9067922, 202)
Affinity DataIC50:  37nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM165864(US9067922, 203)
Affinity DataIC50:  37nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM165797(US9067922, 132)
Affinity DataIC50:  38nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM165727(US9067922, 61)
Affinity DataIC50:  39nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM165809(US9067922, 144)
Affinity DataIC50:  40nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM165806(US9067922, 141)
Affinity DataIC50:  43nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM165743(US9067922, 77)
Affinity DataIC50:  43nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM165677(US9067922, 12)
Affinity DataIC50:  47nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM165713(US9067922, 47)
Affinity DataIC50:  50nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM165817(US9067922, 152)
Affinity DataIC50:  50nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM165832(US9067922, 167)
Affinity DataIC50:  50nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM165822(US9067922, 157)
Affinity DataIC50:  51nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM165709(US9067922, 43)
Affinity DataIC50:  53nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM165861(US9067922, 200)
Affinity DataIC50:  53nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM165892(US9067922, 231)
Affinity DataIC50:  53nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM165813(US9067922, 148)
Affinity DataIC50:  53nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM165704(US9067922, 38)
Affinity DataIC50:  55nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM165685(US9067922, 19)
Affinity DataIC50:  57nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM165742(US9067922, 76)
Affinity DataIC50:  57nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM165692(US9067922, 26)
Affinity DataIC50:  57nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM165772(US9067922, 107)
Affinity DataIC50:  58nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM165891(US9067922, 230)
Affinity DataIC50:  62nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM165673(US9067922, 7)
Affinity DataIC50:  64nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM165779(US9067922, 114)
Affinity DataIC50:  69nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM165679(US9067922, 10)
Affinity DataIC50:  74nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM165776(US9067922, 111)
Affinity DataIC50:  74nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM165862(US9067922, 201)
Affinity DataIC50:  74nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM165807(US9067922, 142)
Affinity DataIC50:  75nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM165738(US9067922, 72)
Affinity DataIC50:  77nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM165697(US9067922, 31)
Affinity DataIC50:  78nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM165808(US9067922, 143)
Affinity DataIC50:  79nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM165705(US9067922, 39)
Affinity DataIC50:  80nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM165700(US9067922, 34)
Affinity DataIC50:  80nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM165678(US9067922, 13)
Affinity DataIC50:  84nMpH: 7.4Assay Description:Assay compound plates were prepared by diluting the compounds of formula (I) with chloride-free buffer (125 mM Na-gluconate, 4.8 mM K-gluconate, 1.3 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
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