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maximum 50k data
Found 27 Enz. Inhib. hit(s) with all data for entry = 7030
TargetAurora kinase A(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM47224(US9073917, 2-inventive)
Affinity DataIC50:  1nMAssay Description:Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM47224(US9073917, 2-inventive)
Affinity DataIC50:  1nMAssay Description:The effect of the compounds of the invention on the activity of the enzyme PDE3 was evaluated by the company CEREP (Le bois I'Evêque, 86600 Celle...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM167515(US9073917, 12- comparative)
Affinity DataIC50:  3nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM167510(US9073917, 7- comparative)
Affinity DataIC50:  3nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM167510(US9073917, 7- comparative)
Affinity DataIC50:  4nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM167515(US9073917, 12- comparative)
Affinity DataIC50:  4nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM167506(US9073917, 1-inventive)
Affinity DataIC50:  4nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM167508(US9073917, 5- comparative)
Affinity DataIC50:  6nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM167507(US9073917, 4- comparative)
Affinity DataIC50:  6nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM167506(US9073917, 1-inventive)
Affinity DataIC50:  6nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM167512(US9073917, 11- comparative | US9073917, 9- compara...)
Affinity DataIC50:  8nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM167513(US9073917, 10- comparative)
Affinity DataIC50:  9nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM167516(US9073917, 13- comparative)
Affinity DataIC50:  10nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM167516(US9073917, 13- comparative)
Affinity DataIC50:  11nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM167509(US9073917, 6- comparative)
Affinity DataIC50:  13nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM167512(US9073917, 11- comparative | US9073917, 9- compara...)
Affinity DataIC50:  15nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM167511(US9073917, 8- comparative)
Affinity DataIC50:  21nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM167513(US9073917, 10- comparative)
Affinity DataIC50:  22nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM167508(US9073917, 5- comparative)
Affinity DataIC50:  23nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM167515(US9073917, 12- comparative)
Affinity DataIC50:  68nMAssay Description:The effect of the compounds of the invention on the activity of the enzyme PDE3 was evaluated by the company CEREP (Le bois I'Evêque, 86600 Celle...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM167507(US9073917, 4- comparative)
Affinity DataIC50:  72nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM167511(US9073917, 8- comparative)
Affinity DataIC50:  102nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM167512(US9073917, 11- comparative | US9073917, 9- compara...)
Affinity DataIC50:  107nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM167509(US9073917, 6- comparative)
Affinity DataIC50:  109nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM60452(US9073917, 3-comparative)
Affinity DataIC50:  900nMAssay Description:The effect of the compounds of the invention on the activity of the enzyme PDE3 was evaluated by the company CEREP (Le bois I'Evêque, 86600 Celle...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM167512(US9073917, 11- comparative | US9073917, 9- compara...)
Affinity DataIC50:  1.76E+3nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM60452(US9073917, 3-comparative)
Affinity DataIC50:  3.80E+3nMAssay Description:The effect of the compounds of the invention on the activity of the enzyme PDE3 was evaluated by the company CEREP (Le bois I'Evêque, 86600 Celle...More data for this Ligand-Target Pair
In DepthDetails US Patent