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Found 9 Enz. Inhib. hit(s) with all data for entry = 7070
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Thesan Pharmaceuticals

US Patent
LigandPNGBDBM172452(US9090625, 4 | US9260450, 4 | US9938289, 4)
Affinity DataIC50:  4.33nMAssay Description:Pharmacol 2002, 62 58-62) The compounds named in the specified Examples were tested as follows for inhibition of ALK-5 autophosphorylation activity a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Thesan Pharmaceuticals

US Patent
LigandPNGBDBM172455(US9090625, 7 | US9260450, 7 | US9938289, 7)
Affinity DataIC50:  6.65nMAssay Description:Pharmacol 2002, 62 58-62) The compounds named in the specified Examples were tested as follows for inhibition of ALK-5 autophosphorylation activity a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Thesan Pharmaceuticals

US Patent
LigandPNGBDBM172457(US9090625, 12 | US9260450, 12 | US9938289, 12)
Affinity DataIC50:  7.94nMAssay Description:Pharmacol 2002, 62 58-62) The compounds named in the specified Examples were tested as follows for inhibition of ALK-5 autophosphorylation activity a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Thesan Pharmaceuticals

US Patent
LigandPNGBDBM172453(US9090625, 5 | US9260450, 5 | US9938289, 5)
Affinity DataIC50:  12.9nMAssay Description:Pharmacol 2002, 62 58-62) The compounds named in the specified Examples were tested as follows for inhibition of ALK-5 autophosphorylation activity a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Thesan Pharmaceuticals

US Patent
LigandPNGBDBM172458(US9090625, 13 | US9260450, 13 | US9938289, 13)
Affinity DataIC50:  18.9nMAssay Description:Pharmacol 2002, 62 58-62) The compounds named in the specified Examples were tested as follows for inhibition of ALK-5 autophosphorylation activity a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Thesan Pharmaceuticals

US Patent
LigandPNGBDBM172449(US9090625, 1 | US9260450, 1 | US9938289, 1)
Affinity DataIC50:  23.4nMAssay Description:Pharmacol 2002, 62 58-62) The compounds named in the specified Examples were tested as follows for inhibition of ALK-5 autophosphorylation activity a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Thesan Pharmaceuticals

US Patent
LigandPNGBDBM172454(US9090625, 6 | US9260450, 6 | US9938289, 6)
Affinity DataIC50:  35.2nMAssay Description:Pharmacol 2002, 62 58-62) The compounds named in the specified Examples were tested as follows for inhibition of ALK-5 autophosphorylation activity a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Thesan Pharmaceuticals

US Patent
LigandPNGBDBM172450(US9090625, 2 | US9260450, 2 | US9938289, 2)
Affinity DataIC50:  94.1nMAssay Description:Pharmacol 2002, 62 58-62) The compounds named in the specified Examples were tested as follows for inhibition of ALK-5 autophosphorylation activity a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Thesan Pharmaceuticals

US Patent
LigandPNGBDBM172451(US9090625, 3 | US9260450, 3 | US9938289, 3)
Affinity DataIC50:  108nMAssay Description:Pharmacol 2002, 62 58-62) The compounds named in the specified Examples were tested as follows for inhibition of ALK-5 autophosphorylation activity a...More data for this Ligand-Target Pair
In DepthDetails US Patent