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Found 10 Enz. Inhib. hit(s) with all data for entry = 7185
TargetD(2) dopamine receptor(Homo sapiens (Human))
Neurogastrx

US Patent
LigandPNGBDBM179867(US11147820, Compound Metopimazine | US9132134, Met...)
Affinity DataKi:  0.0700nMAssay Description:The pharmacological profile of metopimazine, metopimazine acid (MPZA), domperidone, and metoclopramide were assessed by radioligand binding and by a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Neurogastrx

US Patent
LigandPNGBDBM179867(US11147820, Compound Metopimazine | US9132134, Met...)
Affinity DataKi:  0.610nMAssay Description:The pharmacological profile of metopimazine, metopimazine acid (MPZA), domperidone, and metoclopramide were assessed by radioligand binding and by a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
Neurogastrx

US Patent
LigandPNGBDBM50241107(1-(3-(4-(5-chloro-2-oxo-2,3-dihydrobenzo[d]imidazo...)
Affinity DataKi:  1.30nMAssay Description:The pharmacological profile of metopimazine, metopimazine acid (MPZA), domperidone, and metoclopramide were assessed by radioligand binding and by a ...More data for this Ligand-Target Pair
In DepthDetails US PatentDrugBank

TargetD(3) dopamine receptor(Homo sapiens (Human))
Neurogastrx

US Patent
LigandPNGBDBM50241107(1-(3-(4-(5-chloro-2-oxo-2,3-dihydrobenzo[d]imidazo...)
Affinity DataKi:  7.5nMAssay Description:The pharmacological profile of metopimazine, metopimazine acid (MPZA), domperidone, and metoclopramide were assessed by radioligand binding and by a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H1 receptor(Homo sapiens (Human))
Neurogastrx

US Patent
LigandPNGBDBM179867(US11147820, Compound Metopimazine | US9132134, Met...)
Affinity DataKi:  8.40nMAssay Description:The pharmacological profile of metopimazine, metopimazine acid (MPZA), domperidone, and metoclopramide were assessed by radioligand binding and by a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
Neurogastrx

US Patent
LigandPNGBDBM179868(US11147820, Compound Metopimazine acid | US9132134...)
Affinity DataKi:  14nMAssay Description:The pharmacological profile of metopimazine, metopimazine acid (MPZA), domperidone, and metoclopramide were assessed by radioligand binding and by a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(3) dopamine receptor(Homo sapiens (Human))
Neurogastrx

US Patent
LigandPNGBDBM48320(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Affinity DataKi:  16nMAssay Description:The pharmacological profile of metopimazine, metopimazine acid (MPZA), domperidone, and metoclopramide were assessed by radioligand binding and by a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
Neurogastrx

US Patent
LigandPNGBDBM48320(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)
Affinity DataKi:  64nMAssay Description:The pharmacological profile of metopimazine, metopimazine acid (MPZA), domperidone, and metoclopramide were assessed by radioligand binding and by a ...More data for this Ligand-Target Pair
In DepthDetails US PatentDrugBank

TargetD(3) dopamine receptor(Homo sapiens (Human))
Neurogastrx

US Patent
LigandPNGBDBM179868(US11147820, Compound Metopimazine acid | US9132134...)
Affinity DataKi: >100nMAssay Description:The pharmacological profile of metopimazine, metopimazine acid (MPZA), domperidone, and metoclopramide were assessed by radioligand binding and by a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistamine H1 receptor(Homo sapiens (Human))
Neurogastrx

US Patent
LigandPNGBDBM179868(US11147820, Compound Metopimazine acid | US9132134...)
Affinity DataKi:  140nMAssay Description:The pharmacological profile of metopimazine, metopimazine acid (MPZA), domperidone, and metoclopramide were assessed by radioligand binding and by a ...More data for this Ligand-Target Pair
In DepthDetails US Patent