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Found 8 Enz. Inhib. hit(s) with all data for entry = 7240
TargetCytochrome P450 3A4(Homo sapiens (Human))
Innocrin Pharmaceuticals

US Patent
LigandPNGBDBM60666(US9150527, Ketoconazole)
Affinity DataIC50:  150nMAssay Description:CYP17 activity was assayed according to the following procedure. Solutions of each test compound and isozyme inhibitor (ketoconazole) were separately...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Innocrin Pharmaceuticals

US Patent
LigandPNGBDBM50015370(CHEMBL3264599 | US9150527, 2)
Affinity DataIC50:  290nMAssay Description:CYP17 activity was assayed according to the following procedure. Solutions of each test compound and isozyme inhibitor (ketoconazole) were separately...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Innocrin Pharmaceuticals

US Patent
LigandPNGBDBM60666(US9150527, Ketoconazole)
Affinity DataIC50:  400nMAssay Description:CYP17 activity was assayed according to the following procedure. Solutions of each test compound and isozyme inhibitor (ketoconazole) were separately...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 3A4(Homo sapiens (Human))
Innocrin Pharmaceuticals

US Patent
LigandPNGBDBM50015370(CHEMBL3264599 | US9150527, 2)
Affinity DataIC50:  770nMAssay Description:CYP17 activity was assayed according to the following procedure. Solutions of each test compound and isozyme inhibitor (ketoconazole) were separately...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2C19(Homo sapiens (Human))
Innocrin Pharmaceuticals

US Patent
LigandPNGBDBM50015370(CHEMBL3264599 | US9150527, 2)
Affinity DataIC50:  3.00E+3nMAssay Description:CYP17 activity was assayed according to the following procedure. Solutions of each test compound and isozyme inhibitor (ketoconazole) were separately...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2C19(Homo sapiens (Human))
Innocrin Pharmaceuticals

US Patent
LigandPNGBDBM60666(US9150527, Ketoconazole)
Affinity DataIC50:  1.90E+4nMAssay Description:CYP17 activity was assayed according to the following procedure. Solutions of each test compound and isozyme inhibitor (ketoconazole) were separately...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2C9(Homo sapiens (Human))
Innocrin Pharmaceuticals

US Patent
LigandPNGBDBM50015370(CHEMBL3264599 | US9150527, 2)
Affinity DataIC50:  3.30E+4nMAssay Description:CYP17 activity was assayed according to the following procedure. Solutions of each test compound and isozyme inhibitor (ketoconazole) were separately...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2C9(Homo sapiens (Human))
Innocrin Pharmaceuticals

US Patent
LigandPNGBDBM60666(US9150527, Ketoconazole)
Affinity DataIC50:  4.00E+4nMAssay Description:CYP17 activity was assayed according to the following procedure. Solutions of each test compound and isozyme inhibitor (ketoconazole) were separately...More data for this Ligand-Target Pair
In DepthDetails US Patent