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Found 5 Enz. Inhib. hit(s) with all data for entry = 7431
TargetCoagulation factor X(Homo sapiens (Human))
Portola Pharmaceuticals

US Patent
LigandPNGBDBM194506(US9200268, Table 4, Compound 2)
Affinity DataIC50:  24nMpH: 7.4 T: 2°CAssay Description:All assays, which are performed in 96-well microtiter plates, measure proteolytic activity of the enzyme (factor Xa) by following cleavage of a paran...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCoagulation factor X(Homo sapiens (Human))
Portola Pharmaceuticals

US Patent
LigandPNGBDBM194508(US9200268, Table 4, Compound 4)
Affinity DataIC50:  158nMpH: 7.4 T: 2°CAssay Description:All assays, which are performed in 96-well microtiter plates, measure proteolytic activity of the enzyme (factor Xa) by following cleavage of a paran...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCoagulation factor X(Homo sapiens (Human))
Portola Pharmaceuticals

US Patent
LigandPNGBDBM194505(US9200268, Table 4, Compound 1)
Affinity DataIC50:  227nMpH: 7.4 T: 2°CAssay Description:All assays, which are performed in 96-well microtiter plates, measure proteolytic activity of the enzyme (factor Xa) by following cleavage of a paran...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCoagulation factor X(Homo sapiens (Human))
Portola Pharmaceuticals

US Patent
LigandPNGBDBM194509(US9200268, Table 4, Compound 5)
Affinity DataIC50:  320nMpH: 7.4 T: 2°CAssay Description:All assays, which are performed in 96-well microtiter plates, measure proteolytic activity of the enzyme (factor Xa) by following cleavage of a paran...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCoagulation factor X(Homo sapiens (Human))
Portola Pharmaceuticals

US Patent
LigandPNGBDBM194507(US9200268, Table 4, Compound 3)
Affinity DataIC50:  615nMpH: 7.4 T: 2°CAssay Description:All assays, which are performed in 96-well microtiter plates, measure proteolytic activity of the enzyme (factor Xa) by following cleavage of a paran...More data for this Ligand-Target Pair
In DepthDetails US Patent