Found 60 Enz. Inhib. hit(s) with all data for entry = 8179 TargetD(2) dopamine receptor(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataKi: 0.5nM ΔG°: -54.0kJ/mole IC50: 2.56nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataKi: 1.24nM ΔG°: -51.7kJ/mole IC50: 2.52nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataKi: 2.53nM ΔG°: -49.9kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds to D1 and D2 dopamine receptors were determined by competition binding assays. Membrane homogenates of HEK293T cells were s...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataKi: 2.94nM ΔG°: -49.5kJ/mole IC50: 5.67nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataKi: 3.70nM ΔG°: -48.9kJ/mole IC50: 7.22nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataKi: 3.70nM ΔG°: -48.9kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds to D1 and D2 dopamine receptors were determined by competition binding assays. Membrane homogenates of HEK293T cells were s...More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataKi: 4.20nM ΔG°: -48.6kJ/mole IC50: 8.19nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataKi: 5.18nM ΔG°: -48.1kJ/mole IC50: 9.85nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataKi: 6.72nM ΔG°: -47.4kJ/mole IC50: 13.3nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataKi: 6.72nM ΔG°: -47.4kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds to D1 and D2 dopamine receptors were determined by competition binding assays. Membrane homogenates of HEK293T cells were s...More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataKi: 7.51nM ΔG°: -47.1kJ/mole IC50: 14.7nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataKi: 17.3nM ΔG°: -45.0kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds to D1 and D2 dopamine receptors were determined by competition binding assays. Membrane homogenates of HEK293T cells were s...More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataKi: 23.6nM ΔG°: -44.3kJ/mole IC50: 47.9nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataKi: 23.6nM ΔG°: -44.3kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds to D1 and D2 dopamine receptors were determined by competition binding assays. Membrane homogenates of HEK293T cells were s...More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataKi: 25.3nM ΔG°: -44.1kJ/mole IC50: 49.2nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataKi: 28.9nM ΔG°: -43.8kJ/mole IC50: 56.4nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataKi: 28.9nM ΔG°: -43.8kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds to D1 and D2 dopamine receptors were determined by competition binding assays. Membrane homogenates of HEK293T cells were s...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataKi: 32.2nM ΔG°: -43.5kJ/mole IC50: 91.1nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataKi: 40.6nM ΔG°: -42.9kJ/mole IC50: 51.5nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataKi: 50.1nM ΔG°: -42.4kJ/mole IC50: 101nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataKi: 64.1nM ΔG°: -41.7kJ/mole IC50: 114nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataKi: 64.1nM ΔG°: -41.7kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds to D1 and D2 dopamine receptors were determined by competition binding assays. Membrane homogenates of HEK293T cells were s...More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataKi: 74.5nM ΔG°: -41.4kJ/mole IC50: 142nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataKi: 74.5nM ΔG°: -41.4kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds to D1 and D2 dopamine receptors were determined by competition binding assays. Membrane homogenates of HEK293T cells were s...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataKi: 147nM ΔG°: -39.7kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds to D1 and D2 dopamine receptors were determined by competition binding assays. Membrane homogenates of HEK293T cells were s...More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataKi: 148nM ΔG°: -39.6kJ/mole IC50: 300nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataKi: 161nM ΔG°: -39.4kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds to D1 and D2 dopamine receptors were determined by competition binding assays. Membrane homogenates of HEK293T cells were s...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataKi: 161nM ΔG°: -39.4kJ/mole IC50: 456nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataKi: 182nM ΔG°: -39.1kJ/mole IC50: 324nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataKi: 208nM ΔG°: -38.8kJ/mole IC50: 416nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataKi: 224nM ΔG°: -38.6kJ/mole IC50: 1.16E+3nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataKi: 240nM ΔG°: -38.4kJ/mole IC50: 1.24E+3nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataKi: 247nM ΔG°: -38.3kJ/mole IC50: 370nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataKi: 248nM ΔG°: -38.3kJ/mole IC50: 484nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataKi: 320nM ΔG°: -37.7kJ/mole IC50: 648nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataKi: 334nM ΔG°: -37.6kJ/mole IC50: 1.73E+3nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataKi: 338nM ΔG°: -37.6kJ/mole IC50: 684nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataKi: 377nM ΔG°: -37.3kJ/mole IC50: 763nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataKi: 485nM ΔG°: -36.6kJ/mole IC50: 2.51E+3nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataKi: 493nM ΔG°: -36.6kJ/mole IC50: 626nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataKi: 497nM ΔG°: -36.6kJ/mole IC50: 631nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataKi: 498nM ΔG°: -36.6kJ/mole IC50: 1.01E+3nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataKi: 522nM ΔG°: -36.5kJ/mole IC50: 1.06E+3nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataKi: 600nM ΔG°: -36.1kJ/mole IC50: 758nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataKi: 730nM ΔG°: -35.6kJ/mole IC50: 922nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataKi: 741nM ΔG°: -35.6kJ/mole IC50: 1.50E+3nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataKi: 1.00E+3nM ΔG°: -34.8kJ/mole IC50: 2.03E+3nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataKi: 1.44E+3nM ΔG°: -33.9kJ/mole IC50: 2.92E+3nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataIC50: 462nMT: 2°CAssay Description:Each medicament was dissolved in serum-free F12 culture medium containing 100 μM of IBMX. CHO cells which can stably express D2 receptor were pre-...More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
US Patent
Affinity DataIC50: 740nMpH: 7.5Assay Description:For detecting the agonism action of the compounds, the [35S]GTPγS binding assay was performed at 30° C. for 40 mins in reaction buffer containin...More data for this Ligand-Target Pair
