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Found 6 Enz. Inhib. hit(s) with all data for entry = 8554
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Ixaltis

US Patent
LigandPNGBDBM50278564(CHEMBL471036 | Litoxetine | US9511061, Compound A)
Affinity DataKi:  200nM IC50:  250nMAssay Description:The affinity of the compound A was evaluated in vitro on 8 cloned human serotoninergic receptors by measuring the specific binding of the ligands to ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Ixaltis

US Patent
LigandPNGBDBM50278564(CHEMBL471036 | Litoxetine | US9511061, Compound A)
Affinity DataKi:  620nM IC50:  1.00E+3nMAssay Description:The affinity of the compound A was evaluated in vitro on 8 cloned human serotoninergic receptors by measuring the specific binding of the ligands to ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Ixaltis

US Patent
LigandPNGBDBM50278564(CHEMBL471036 | Litoxetine | US9511061, Compound A)
Affinity DataKi:  720nM IC50:  1.40E+3nMAssay Description:The affinity of the compound A was evaluated in vitro on 8 cloned human serotoninergic receptors by measuring the specific binding of the ligands to ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Ixaltis

US Patent
LigandPNGBDBM50278564(CHEMBL471036 | Litoxetine | US9511061, Compound A)
Affinity DataKi:  980nM IC50:  1.00E+3nMAssay Description:The affinity of the compound A was evaluated in vitro on 8 cloned human serotoninergic receptors by measuring the specific binding of the ligands to ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetIsoform 5-HT4(E) of 5-hydroxytryptamine receptor 4 (H5-HT4(g))(Homo sapiens (Human))
Ixaltis

US Patent
LigandPNGBDBM50278564(CHEMBL471036 | Litoxetine | US9511061, Compound A)
Affinity DataKi:  1.60E+3nM IC50:  4.70E+3nMAssay Description:The affinity of the compound A was evaluated in vitro on 8 cloned human serotoninergic receptors by measuring the specific binding of the ligands to ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Ixaltis

US Patent
LigandPNGBDBM50278564(CHEMBL471036 | Litoxetine | US9511061, Compound A)
Affinity DataKi:  2.60E+3nM IC50:  7.20E+3nMAssay Description:The affinity of the compound A was evaluated in vitro on 8 cloned human serotoninergic receptors by measuring the specific binding of the ligands to ...More data for this Ligand-Target Pair
In DepthDetails US Patent