Compile Data Set for Download or QSAR
maximum 50k data
Found 71 Enz. Inhib. hit(s) with all data for entry = 8580
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50054344(CHEMBL3319356 | US9522881, 11a-1 L97M74 | US984453...)
Affinity DataIC50:  200nMpH: 7.0Assay Description:The inhibition assays were performed at 25° C. in 50 mM 3,3-dimethylglutarate buffer, pH 7.0, containing 1 mM EDTA with an ionic strength of 0.15M ad...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50054344(CHEMBL3319356 | US9522881, 11a-1 L97M74 | US984453...)
Affinity DataIC50:  200nMAssay Description:For selectivity studies, the PTPs, including LYP, mPTPA, SHP1-D1C, PTP1B, LMPTP, VHR, Laforin and PTPα-D1D2 were expressed and purified from E. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50054344(CHEMBL3319356 | US9522881, 11a-1 L97M74 | US984453...)
Affinity DataIC50:  200nMpH: 7.0Assay Description:The inhibition assays were performed at 25° C. in 50 mM 3,3-dimethylglutarate buffer, pH 7.0, containing 1 mM EDTA with an ionic strength of 0.15M ad...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50054257(CHEMBL3319376 | US9522881, 11a-21 L97L08 | US98445...)
Affinity DataIC50:  220nMpH: 7.0Assay Description:The inhibition assays were performed at 25° C. in 50 mM 3,3-dimethylglutarate buffer, pH 7.0, containing 1 mM EDTA with an ionic strength of 0.15M ad...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50054258(CHEMBL3319377 | US9522881, 11a-22 L97L07 | US98445...)
Affinity DataIC50:  310nMpH: 7.0Assay Description:The inhibition assays were performed at 25° C. in 50 mM 3,3-dimethylglutarate buffer, pH 7.0, containing 1 mM EDTA with an ionic strength of 0.15M ad...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50054259(CHEMBL3319378 | US9522881, 11a-23 L97L03)
Affinity DataIC50:  370nMpH: 7.0Assay Description:The inhibition assays were performed at 25° C. in 50 mM 3,3-dimethylglutarate buffer, pH 7.0, containing 1 mM EDTA with an ionic strength of 0.15M ad...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50054260(CHEMBL3319379 | US9522881, 11a-24 L97L05 | US98445...)
Affinity DataIC50:  380nMpH: 7.0Assay Description:The inhibition assays were performed at 25° C. in 50 mM 3,3-dimethylglutarate buffer, pH 7.0, containing 1 mM EDTA with an ionic strength of 0.15M ad...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50054261(CHEMBL3319380 | US9522881, 11a-25 L97L06 | US98445...)
Affinity DataIC50:  420nMpH: 7.0Assay Description:The inhibition assays were performed at 25° C. in 50 mM 3,3-dimethylglutarate buffer, pH 7.0, containing 1 mM EDTA with an ionic strength of 0.15M ad...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50054406(CHEMBL3319357 | US9522881, 11a-2 (L97N08) | US9844...)
Affinity DataIC50:  620nMpH: 7.0Assay Description:The inhibition assays were performed at 25° C. in 50 mM 3,3-dimethylglutarate buffer, pH 7.0, containing 1 mM EDTA with an ionic strength of 0.15M ad...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50054262(CHEMBL3319381 | US9522881, 11a-26 L97L02 | US98445...)
Affinity DataIC50:  630nMpH: 7.0Assay Description:The inhibition assays were performed at 25° C. in 50 mM 3,3-dimethylglutarate buffer, pH 7.0, containing 1 mM EDTA with an ionic strength of 0.15M ad...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50054405(CHEMBL3319358 | US9522881, 11a-3 (L97M50) | US9844...)
Affinity DataIC50:  660nMpH: 7.0Assay Description:The inhibition assays were performed at 25° C. in 50 mM 3,3-dimethylglutarate buffer, pH 7.0, containing 1 mM EDTA with an ionic strength of 0.15M ad...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50054404(CHEMBL3319359 | US9522881, 11a-4 (L97M61) | US9844...)
Affinity DataIC50:  760nMpH: 7.0Assay Description:The inhibition assays were performed at 25° C. in 50 mM 3,3-dimethylglutarate buffer, pH 7.0, containing 1 mM EDTA with an ionic strength of 0.15M ad...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50054403(CHEMBL3319360 | US9522881, 11a-5 (L97M48) | US9844...)
Affinity DataIC50:  770nMpH: 7.0Assay Description:The inhibition assays were performed at 25° C. in 50 mM 3,3-dimethylglutarate buffer, pH 7.0, containing 1 mM EDTA with an ionic strength of 0.15M ad...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50054402(CHEMBL3319361 | US9522881, 11a-6 (L97M52) | US9844...)
Affinity DataIC50:  860nMpH: 7.0Assay Description:The inhibition assays were performed at 25° C. in 50 mM 3,3-dimethylglutarate buffer, pH 7.0, containing 1 mM EDTA with an ionic strength of 0.15M ad...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 7(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50054344(CHEMBL3319356 | US9522881, 11a-1 L97M74 | US984453...)
Affinity DataIC50:  1.03E+3nMAssay Description:For selectivity studies, the PTPs, including LYP, mPTPA, SHP1-D1C, PTP1B, LMPTP, VHR, Laforin and PTPα-D1D2 were expressed and purified from E. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50054401(CHEMBL3319362 | US9522881, 11a-7 (L97M93) | US9844...)
Affinity DataIC50:  1.05E+3nMpH: 7.0Assay Description:The inhibition assays were performed at 25° C. in 50 mM 3,3-dimethylglutarate buffer, pH 7.0, containing 1 mM EDTA with an ionic strength of 0.15M ad...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50054344(CHEMBL3319356 | US9522881, 11a-1 L97M74 | US984453...)
Affinity DataIC50:  1.05E+3nMAssay Description:For selectivity studies, the PTPs, including LYP, mPTPA, SHP1-D1C, PTP1B, LMPTP, VHR, Laforin and PTPα-D1D2 were expressed and purified from E. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 3(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50054344(CHEMBL3319356 | US9522881, 11a-1 L97M74 | US984453...)
Affinity DataIC50:  1.07E+3nMAssay Description:For selectivity studies, the PTPs, including LYP, mPTPA, SHP1-D1C, PTP1B, LMPTP, VHR, Laforin and PTPα-D1D2 were expressed and purified from E. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein phosphatase 2A activator(Mouse)
Indiana University Research And Technology

US Patent
LigandPNGBDBM50054344(CHEMBL3319356 | US9522881, 11a-1 L97M74 | US984453...)
Affinity DataIC50:  1.09E+3nMAssay Description:For selectivity studies, the PTPs, including LYP, mPTPA, SHP1-D1C, PTP1B, LMPTP, VHR, Laforin and PTPα-D1D2 were expressed and purified from E. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50054400(CHEMBL3319363 | US9522881, 11a-8 (L97M24) | US9844...)
Affinity DataIC50:  1.20E+3nMpH: 7.0Assay Description:The inhibition assays were performed at 25° C. in 50 mM 3,3-dimethylglutarate buffer, pH 7.0, containing 1 mM EDTA with an ionic strength of 0.15M ad...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50054399(CHEMBL3319364 | US9522881, 11a-9 (L97M77))
Affinity DataIC50:  1.25E+3nMpH: 7.0Assay Description:The inhibition assays were performed at 25° C. in 50 mM 3,3-dimethylglutarate buffer, pH 7.0, containing 1 mM EDTA with an ionic strength of 0.15M ad...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRNA polymerase II subunit A C-terminal domain phosphatase SSU72(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50054344(CHEMBL3319356 | US9522881, 11a-1 L97M74 | US984453...)
Affinity DataIC50:  1.30E+3nMAssay Description:For selectivity studies, the PTPs, including LYP, mPTPA, SHP1-D1C, PTP1B, LMPTP, VHR, Laforin and PTPα-D1D2 were expressed and purified from E. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50054350(CHEMBL3319365 | US9522881, 11a-10 (L97N15) | US984...)
Affinity DataIC50:  1.35E+3nMpH: 7.0Assay Description:The inhibition assays were performed at 25° C. in 50 mM 3,3-dimethylglutarate buffer, pH 7.0, containing 1 mM EDTA with an ionic strength of 0.15M ad...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50054344(CHEMBL3319356 | US9522881, 11a-1 L97M74 | US984453...)
Affinity DataIC50:  1.44E+3nMAssay Description:For selectivity studies, the PTPs, including LYP, mPTPA, SHP1-D1C, PTP1B, LMPTP, VHR, Laforin and PTPα-D1D2 were expressed and purified from E. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50054349(CHEMBL3319366 | US9522881, 11a-11 (L97M21) | US984...)
Affinity DataIC50:  1.46E+3nMpH: 7.0Assay Description:The inhibition assays were performed at 25° C. in 50 mM 3,3-dimethylglutarate buffer, pH 7.0, containing 1 mM EDTA with an ionic strength of 0.15M ad...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50054348(CHEMBL3319367 | US9522881, 11a-12 (L97M63) | US984...)
Affinity DataIC50:  1.49E+3nMpH: 7.0Assay Description:The inhibition assays were performed at 25° C. in 50 mM 3,3-dimethylglutarate buffer, pH 7.0, containing 1 mM EDTA with an ionic strength of 0.15M ad...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM260051(US9522881, 7'c-3 (L95M50))
Affinity DataIC50:  1.60E+3nMpH: 7.0Assay Description:The inhibition assays were performed at 25° C. in 50 mM 3,3-dimethylglutarate buffer, pH 7.0, containing 1 mM EDTA with an ionic strength of 0.15M ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50054347(CHEMBL3319368 | US9522881, 11a-13 (L97M30) | US984...)
Affinity DataIC50:  1.76E+3nMpH: 7.0Assay Description:The inhibition assays were performed at 25° C. in 50 mM 3,3-dimethylglutarate buffer, pH 7.0, containing 1 mM EDTA with an ionic strength of 0.15M ad...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50054346(CHEMBL3319369 | US9522881, 11a-14 (L97M73) | US984...)
Affinity DataIC50:  1.79E+3nMpH: 7.0Assay Description:The inhibition assays were performed at 25° C. in 50 mM 3,3-dimethylglutarate buffer, pH 7.0, containing 1 mM EDTA with an ionic strength of 0.15M ad...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50054345(CHEMBL3319370 | US9522881, 11a-15 (L97N95) | US984...)
Affinity DataIC50:  1.84E+3nMpH: 7.0Assay Description:The inhibition assays were performed at 25° C. in 50 mM 3,3-dimethylglutarate buffer, pH 7.0, containing 1 mM EDTA with an ionic strength of 0.15M ad...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50054344(CHEMBL3319356 | US9522881, 11a-1 L97M74 | US984453...)
Affinity DataIC50:  2.29E+3nMAssay Description:For selectivity studies, the PTPs, including LYP, mPTPA, SHP1-D1C, PTP1B, LMPTP, VHR, Laforin and PTPα-D1D2 were expressed and purified from E. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50054264(CHEMBL3319383 | US9522881, 11c-1 (L88M74))
Affinity DataIC50:  2.30E+3nMpH: 7.0Assay Description:The inhibition assays were performed at 25° C. in 50 mM 3,3-dimethylglutarate buffer, pH 7.0, containing 1 mM EDTA with an ionic strength of 0.15M ad...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDual specificity protein phosphatase 23(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50054344(CHEMBL3319356 | US9522881, 11a-1 L97M74 | US984453...)
Affinity DataIC50:  2.30E+3nMAssay Description:For selectivity studies, the PTPs, including LYP, mPTPA, SHP1-D1C, PTP1B, LMPTP, VHR, Laforin and PTPα-D1D2 were expressed and purified from E. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50054206(CHEMBL3319371 | US9522881, 11a-16 (L97N13) | US984...)
Affinity DataIC50:  2.31E+3nMpH: 7.0Assay Description:The inhibition assays were performed at 25° C. in 50 mM 3,3-dimethylglutarate buffer, pH 7.0, containing 1 mM EDTA with an ionic strength of 0.15M ad...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50054344(CHEMBL3319356 | US9522881, 11a-1 L97M74 | US984453...)
Affinity DataIC50:  2.34E+3nMAssay Description:For selectivity studies, the PTPs, including LYP, mPTPA, SHP1-D1C, PTP1B, LMPTP, VHR, Laforin and PTPα-D1D2 were expressed and purified from E. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50054207(CHEMBL3319372 | US9522881, 11a-17 (L97M32) | US984...)
Affinity DataIC50:  2.39E+3nMpH: 7.0Assay Description:The inhibition assays were performed at 25° C. in 50 mM 3,3-dimethylglutarate buffer, pH 7.0, containing 1 mM EDTA with an ionic strength of 0.15M ad...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM260049(US9522881, 7'c-1 (L95M52))
Affinity DataIC50:  2.40E+3nMpH: 7.0Assay Description:The inhibition assays were performed at 25° C. in 50 mM 3,3-dimethylglutarate buffer, pH 7.0, containing 1 mM EDTA with an ionic strength of 0.15M ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein phosphatase gamma(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50054344(CHEMBL3319356 | US9522881, 11a-1 L97M74 | US984453...)
Affinity DataIC50:  2.40E+3nMAssay Description:For selectivity studies, the PTPs, including LYP, mPTPA, SHP1-D1C, PTP1B, LMPTP, VHR, Laforin and PTPα-D1D2 were expressed and purified from E. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50054209(CHEMBL3319373 | US9522881, 11a-18 (L97M18) | US984...)
Affinity DataIC50:  2.73E+3nMpH: 7.0Assay Description:The inhibition assays were performed at 25° C. in 50 mM 3,3-dimethylglutarate buffer, pH 7.0, containing 1 mM EDTA with an ionic strength of 0.15M ad...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDual specificity protein phosphatase 10(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50054344(CHEMBL3319356 | US9522881, 11a-1 L97M74 | US984453...)
Affinity DataIC50:  2.90E+3nMAssay Description:For selectivity studies, the PTPs, including LYP, mPTPA, SHP1-D1C, PTP1B, LMPTP, VHR, Laforin and PTPα-D1D2 were expressed and purified from E. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDual specificity protein phosphatase 3(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50054344(CHEMBL3319356 | US9522881, 11a-1 L97M74 | US984453...)
Affinity DataIC50:  3.19E+3nMAssay Description:For selectivity studies, the PTPs, including LYP, mPTPA, SHP1-D1C, PTP1B, LMPTP, VHR, Laforin and PTPα-D1D2 were expressed and purified from E. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein phosphatase mu(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50054344(CHEMBL3319356 | US9522881, 11a-1 L97M74 | US984453...)
Affinity DataIC50:  3.30E+3nMAssay Description:For selectivity studies, the PTPs, including LYP, mPTPA, SHP1-D1C, PTP1B, LMPTP, VHR, Laforin and PTPα-D1D2 were expressed and purified from E. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50054265(CHEMBL3319384 | US9522881, 11c-2 (L88M49))
Affinity DataIC50:  3.60E+3nMpH: 7.0Assay Description:The inhibition assays were performed at 25° C. in 50 mM 3,3-dimethylglutarate buffer, pH 7.0, containing 1 mM EDTA with an ionic strength of 0.15M ad...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50054344(CHEMBL3319356 | US9522881, 11a-1 L97M74 | US984453...)
Affinity DataIC50:  4.00E+3nMAssay Description:For selectivity studies, the PTPs, including LYP, mPTPA, SHP1-D1C, PTP1B, LMPTP, VHR, Laforin and PTPα-D1D2 were expressed and purified from E. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM260050(US9522881, 7'c-2 (L95N79))
Affinity DataIC50:  4.20E+3nMpH: 7.0Assay Description:The inhibition assays were performed at 25° C. in 50 mM 3,3-dimethylglutarate buffer, pH 7.0, containing 1 mM EDTA with an ionic strength of 0.15M ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50054267(CHEMBL3319386 | US9522881, 11c-4 (L88M52))
Affinity DataIC50:  4.50E+3nMpH: 7.0Assay Description:The inhibition assays were performed at 25° C. in 50 mM 3,3-dimethylglutarate buffer, pH 7.0, containing 1 mM EDTA with an ionic strength of 0.15M ad...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50054211(CHEMBL3319374 | US9522881, 11a-19 (L97N07) | US984...)
Affinity DataIC50:  4.66E+3nMpH: 7.0Assay Description:The inhibition assays were performed at 25° C. in 50 mM 3,3-dimethylglutarate buffer, pH 7.0, containing 1 mM EDTA with an ionic strength of 0.15M ad...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50054266(CHEMBL3319385 | US9522881, 11c-3 (L88M50))
Affinity DataIC50:  5.00E+3nMpH: 7.0Assay Description:The inhibition assays were performed at 25° C. in 50 mM 3,3-dimethylglutarate buffer, pH 7.0, containing 1 mM EDTA with an ionic strength of 0.15M ad...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM260046(US9522881, 7'a-1 (L89M52))
Affinity DataIC50:  5.00E+3nMpH: 7.0Assay Description:The inhibition assays were performed at 25° C. in 50 mM 3,3-dimethylglutarate buffer, pH 7.0, containing 1 mM EDTA with an ionic strength of 0.15M ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 14(Homo sapiens (Human))
Indiana University Research And Technology

US Patent
LigandPNGBDBM50054344(CHEMBL3319356 | US9522881, 11a-1 L97M74 | US984453...)
Affinity DataIC50:  5.30E+3nMAssay Description:For selectivity studies, the PTPs, including LYP, mPTPA, SHP1-D1C, PTP1B, LMPTP, VHR, Laforin and PTPα-D1D2 were expressed and purified from E. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
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