Compile Data Set for Download or QSAR
maximum 50k data
Found 21 Enz. Inhib. hit(s) with all data for entry = 199
TargetMAP kinase-interacting serine/threonine-protein kinase 1 [1-424](Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM227732(3-bromo-n-(6-isopropoxy-1h-indazol-5-yl)-1h-pyrazo...)
Affinity DataIC50:  1nMpH: 7.5Assay Description:TBDA recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accessio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 1 [1-424](Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM227719(3-bromo-n-(6-methoxy-1h-indazol-5-yl)-1h-pyrazolo[...)
Affinity DataIC50:  1nMpH: 7.5Assay Description:TBDA recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accessio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 1 [1-424](Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM227719(3-bromo-n-(6-methoxy-1h-indazol-5-yl)-1h-pyrazolo[...)
Affinity DataIC50:  2nMpH: 7.5Assay Description:TBDA recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accessio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 1 [1-424](Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM227728(3-(4-fluorophenyl)-n-(6-methoxy-1h-indazol-5-yl)-1...)
Affinity DataIC50:  2nMpH: 7.5Assay Description:TBDA recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accessio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 1 [1-424](Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM227719(3-bromo-n-(6-methoxy-1h-indazol-5-yl)-1h-pyrazolo[...)
Affinity DataIC50:  3nMpH: 7.5Assay Description:TBDA recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accessio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 1 [1-424](Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM227719(3-bromo-n-(6-methoxy-1h-indazol-5-yl)-1h-pyrazolo[...)
Affinity DataIC50:  6nMpH: 7.5Assay Description:TBDA recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accessio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 1 [1-424](Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM227721(3-bromo-n-(1h-indazol-5-yl)-1h-pyrazolo[3,4-d]pyri...)
Affinity DataIC50:  8nMpH: 7.5Assay Description:TBDA recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accessio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 1 [1-424](Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM227720(3-bromo-n-(6-fluoro-1h-indazol-5-yl)-1h-pyrazolo[3...)
Affinity DataIC50:  8nMpH: 7.5Assay Description:TBDA recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accessio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 1 [1-424](Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM227727(3-(4-fluorophenyl)-n-(1h-indazol-5-yl)-1h-pyrazolo...)
Affinity DataIC50:  12nMpH: 7.5Assay Description:TBDA recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accessio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 1 [1-424](Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM227720(3-bromo-n-(6-fluoro-1h-indazol-5-yl)-1h-pyrazolo[3...)
Affinity DataIC50:  12nMpH: 7.5Assay Description:TBDA recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accessio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 1 [1-424](Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM227729(US9556181, 14 | n-(6-fluoro-1h-indazol-5-yl)-3-(4-...)
Affinity DataIC50:  12nMpH: 7.5Assay Description:TBDA recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accessio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 1 [1-424](Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM227721(3-bromo-n-(1h-indazol-5-yl)-1h-pyrazolo[3,4-d]pyri...)
Affinity DataIC50:  14nMpH: 7.5Assay Description:TBDA recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accessio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 1 [1-424](Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM227720(3-bromo-n-(6-fluoro-1h-indazol-5-yl)-1h-pyrazolo[3...)
Affinity DataIC50:  15nMpH: 7.5Assay Description:TBDA recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accessio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 1 [1-424](Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM227732(3-bromo-n-(6-isopropoxy-1h-indazol-5-yl)-1h-pyrazo...)
Affinity DataIC50:  19nMpH: 7.5Assay Description:TBDA recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accessio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 1 [1-424](Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM227734(3-(4-fluorophenyl)-n-(6-isopropoxy-1h-indazol-5-yl...)
Affinity DataIC50:  26nMpH: 7.5Assay Description:TBDA recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accessio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 1 [1-424](Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM227721(3-bromo-n-(1h-indazol-5-yl)-1h-pyrazolo[3,4-d]pyri...)
Affinity DataIC50:  26nMpH: 7.5Assay Description:TBDA recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accessio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 1 [1-424](Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM227732(3-bromo-n-(6-isopropoxy-1h-indazol-5-yl)-1h-pyrazo...)
Affinity DataIC50:  27nMpH: 7.5Assay Description:TBDA recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accessio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 1 [1-424](Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM227717(US9556181, 2 | n-(6-methoxy-1h-indazol-5-yl)-h-pyr...)
Affinity DataIC50:  49nMpH: 7.5Assay Description:TBDA recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accessio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 1 [1-424](Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM227732(3-bromo-n-(6-isopropoxy-1h-indazol-5-yl)-1h-pyrazo...)
Affinity DataIC50:  63nMpH: 7.5Assay Description:TBDA recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accessio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 1 [1-424](Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM227714(US9556181, 1 | n-(1h-indazol-5-yl)-1h-pyrazolo[3,4...)
Affinity DataIC50:  117nMpH: 7.5Assay Description:TBDA recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accessio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 1 [1-424](Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM227718(US9556181, 3 | n-[6-(propan-2-yloxy)-1h-indazol-5-...)
Affinity DataIC50:  531nMpH: 7.5Assay Description:TBDA recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accessio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent