Compile Data Set for Download or QSAR
maximum 50k data
Found 69 Enz. Inhib. hit(s) with all data for entry = 149
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193784(US9670209, Compound 302 1-((R)-3-((1R,3R,5S)-3-(cy...)
Affinity DataEC50:  1.30nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193784(US9670209, Compound 302 1-((R)-3-((1R,3R,5S)-3-(cy...)
Affinity DataEC50:  25nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193784(US9670209, Compound 302 1-((R)-3-((1R,3R,5S)-3-(cy...)
Affinity DataEC50:  160nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193784(US9670209, Compound 302 1-((R)-3-((1R,3R,5S)-3-(cy...)
Affinity DataEC50:  3.20nMT: 2°CAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 ul/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG3-Gal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193785(US9670209, Compound 303 1-((R)-3-((1R,3R,5S)-3-(2-...)
Affinity DataEC50:  4nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193785(US9670209, Compound 303 1-((R)-3-((1R,3R,5S)-3-(2-...)
Affinity DataEC50:  79nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193787(US9670209, Compound 304 1-((R)-3-(3-(Cyclopropylme...)
Affinity DataEC50:  1.30nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193787(US9670209, Compound 304 1-((R)-3-(3-(Cyclopropylme...)
Affinity DataEC50:  25nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193787(US9670209, Compound 304 1-((R)-3-(3-(Cyclopropylme...)
Affinity DataEC50:  40nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193787(US9670209, Compound 304 1-((R)-3-(3-(Cyclopropylme...)
Affinity DataEC50:  5nMT: 2°CAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 ul/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG3-Gal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193788(US9670209, Compound 305 1-((R)-3-((1R,3R,5S)-3-(Al...)
Affinity DataEC50:  7.90nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193788(US9670209, Compound 305 1-((R)-3-((1R,3R,5S)-3-(Al...)
Affinity DataEC50:  130nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193789(US9670209, Compound 307 1-((R)-3-(3-(Cyclopropylme...)
Affinity DataEC50:  0.320nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193789(US9670209, Compound 307 1-((R)-3-(3-(Cyclopropylme...)
Affinity DataEC50:  20nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193789(US9670209, Compound 307 1-((R)-3-(3-(Cyclopropylme...)
Affinity DataEC50:  50nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193789(US9670209, Compound 307 1-((R)-3-(3-(Cyclopropylme...)
Affinity DataEC50:  10nMT: 2°CAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 ul/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG3-Gal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193790(US9670209, Compound 308 1-((R)-3-(3-(Allyloxy)-8-a...)
Affinity DataEC50:  1.30nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193790(US9670209, Compound 308 1-((R)-3-(3-(Allyloxy)-8-a...)
Affinity DataEC50:  40nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193790(US9670209, Compound 308 1-((R)-3-(3-(Allyloxy)-8-a...)
Affinity DataEC50:  500nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193790(US9670209, Compound 308 1-((R)-3-(3-(Allyloxy)-8-a...)
Affinity DataEC50:  79nMT: 2°CAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 ul/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG3-Gal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193791(US9670209, Compound 309 1-((R)-3-(3-(2-Methoxyethy...)
Affinity DataEC50:  0.400nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193791(US9670209, Compound 309 1-((R)-3-(3-(2-Methoxyethy...)
Affinity DataEC50:  32nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193791(US9670209, Compound 309 1-((R)-3-(3-(2-Methoxyethy...)
Affinity DataEC50:  130nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193791(US9670209, Compound 309 1-((R)-3-(3-(2-Methoxyethy...)
Affinity DataEC50:  50nMT: 2°CAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 ul/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG3-Gal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193795(US9670209, Compound 310 1-((R)-3-((1R,3R,5S)-3-(cy...)
Affinity DataEC50:  32nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193800(US9670209, Compound 311 1-((R)-3-(3-(cyclopropylme...)
Affinity DataEC50:  10nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193800(US9670209, Compound 311 1-((R)-3-(3-(cyclopropylme...)
Affinity DataEC50:  130nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193802(US9670209, Compound 312 1-((R)-3-(3-(cyclopropylme...)
Affinity DataEC50:  0.5nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193802(US9670209, Compound 312 1-((R)-3-(3-(cyclopropylme...)
Affinity DataEC50:  32nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193802(US9670209, Compound 312 1-((R)-3-(3-(cyclopropylme...)
Affinity DataEC50:  500nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193802(US9670209, Compound 312 1-((R)-3-(3-(cyclopropylme...)
Affinity DataEC50:  13nMT: 2°CAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 ul/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG3-Gal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193803(US9670209, Compound 313 1-((R)-3-((1R,3R,58)-3-(2-...)
Affinity DataEC50:  6.30nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193803(US9670209, Compound 313 1-((R)-3-((1R,3R,58)-3-(2-...)
Affinity DataEC50:  50nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193804(US9670209, Compound 314 1-((R)-3-((1R,3R,58)-3-(cy...)
Affinity DataEC50:  4nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193804(US9670209, Compound 314 1-((R)-3-((1R,3R,58)-3-(cy...)
Affinity DataEC50:  50nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193805(US9670209, Compound 315 1-((R)-3-(3-(cyclobutylmet...)
Affinity DataEC50:  7.90nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193805(US9670209, Compound 315 1-((R)-3-(3-(cyclobutylmet...)
Affinity DataEC50:  50nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193806(US9670209, Compound 316 1-((R)-3-(3-(cyclopropylme...)
Affinity DataEC50:  13nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193806(US9670209, Compound 316 1-((R)-3-(3-(cyclopropylme...)
Affinity DataEC50:  250nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193807(US9670209, Compound 317 1-((R)-3-(3-(cyclopropylme...)
Affinity DataEC50:  25nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193807(US9670209, Compound 317 1-((R)-3-(3-(cyclopropylme...)
Affinity DataEC50:  130nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193808(US9670209, Compound 318 1-((R)-3-((1R,3R,5S)-3-(pr...)
Affinity DataEC50:  10nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193808(US9670209, Compound 318 1-((R)-3-((1R,3R,5S)-3-(pr...)
Affinity DataEC50:  63nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193815(US9670209, Compound 319 1-((R)-3-(3-(propoxy)-8-az...)
Affinity DataEC50:  7.90nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193815(US9670209, Compound 319 1-((R)-3-(3-(propoxy)-8-az...)
Affinity DataEC50:  32nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193818(US9670209, Compound 320 1-((R)-3-((1R,3R,58)-3-(2-...)
Affinity DataEC50:  6.30nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193818(US9670209, Compound 320 1-((R)-3-((1R,3R,58)-3-(2-...)
Affinity DataEC50:  63nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193819(US9670209, Compound 321 1-((R)-3-(3-(cyclopropylme...)
Affinity DataEC50:  13nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193819(US9670209, Compound 321 1-((R)-3-(3-(cyclopropylme...)
Affinity DataEC50:  7.90nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Acadia Pharmaceuticals

US Patent
LigandPNGBDBM193820(US9670209, Compound 322 1-((R)-3-((1R,3R,5S)-3-(pr...)
Affinity DataEC50:  10nMAssay Description:NIH-3T3 cells were grown in 96-well tissue culture plates to 70% to 80% confluence. Cells were transfected with plasmid DNAs using Superfect Reagent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Displayed 1 to 50 (of 69 total ) | Next | Last >>
Jump to: