Compile Data Set for Download or QSAR
maximum 50k data
Found 112 Enz. Inhib. hit(s) with all data for entry = 122
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Forma Tm

US Patent
LigandPNGBDBM180912(US9676721, 28 2-cyano-1-({4-[(3,4-difluorobenzene)...)
Affinity DataIC50:  0.800nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Forma Tm

US Patent
LigandPNGBDBM180103(US9676721, 32 2-cyano-1-({4-[(3,5-difluorobenzene)...)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Forma Tm

US Patent
LigandPNGBDBM180915(US9676721, 21 1-{2-[4-(benzenesulfonyl)phenyl]ethy...)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Forma Tm

US Patent
LigandPNGBDBM180921(US9676721, 79 2-cyano-1-{[4-(1-methyl-1H-indazole-...)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Forma Tm

US Patent
LigandPNGBDBM180067(US9676721, 17 1-[(4-{[4-chloro-3-(trifluoromethyl)...)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Forma Tm

US Patent
LigandPNGBDBM180928(US9676721, 97 2-cyano-3-(pyridin-4-yl)-1-{[4-(quin...)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Forma Tm

US Patent
LigandPNGBDBM180918(US9676721, 36 2-cyano-1-({4-[(3-fluoro-4-methoxybe...)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Forma Tm

US Patent
LigandPNGBDBM181033(US9676721, 41 2-cyano-1-({4-[(3-methoxy-4-methylbe...)
Affinity DataIC50:  1.20nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
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TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Forma Tm

US Patent
LigandPNGBDBM180064(US9676721, 64 2-cyano-1-[(4-{[3-(dimethylsulfamoyl...)
Affinity DataIC50:  1.30nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
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TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Forma Tm

US Patent
LigandPNGBDBM180081(US9676721, 88 2-cyano-1-{[4-(6-methylpyridine-3-su...)
Affinity DataIC50:  1.40nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
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TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Forma Tm

US Patent
LigandPNGBDBM180272(US9676721, 42 2-cyano-1-({4-[(3-methoxybenzene)sul...)
Affinity DataIC50:  1.5nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
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TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Forma Tm

US Patent
LigandPNGBDBM181032(US9676721, 75 2-cyano-1-[(4-{[4-(morpholin-4-yl)be...)
Affinity DataIC50:  1.5nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
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TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Forma Tm

US Patent
LigandPNGBDBM180257(US9676721, 78 2-cyano-1-{[4-({3-[(morpholin-4-yl)c...)
Affinity DataIC50:  1.70nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
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TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Forma Tm

US Patent
LigandPNGBDBM180786(US9676721, 34 2-cyano-1-({4-[(3-cyanobenzene)sulfo...)
Affinity DataIC50:  1.70nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
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TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Forma Tm

US Patent
LigandPNGBDBM180095(US9676721, 27 2-cyano-1-({4-[(3,4-dichlorobenzene)...)
Affinity DataIC50:  1.70nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
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TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Forma Tm

US Patent
LigandPNGBDBM180920(US9676721, 39 2-cyano-1-({4-[(3-fluoro-5-methylben...)
Affinity DataIC50:  1.70nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
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TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Forma Tm

US Patent
LigandPNGBDBM180101(US9676721, 20 1-{[4-(2H-1,3-benzodioxole-5-sulfony...)
Affinity DataIC50:  1.80nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
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TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Forma Tm

US Patent
LigandPNGBDBM180049(US9676721, 65 2-cyano-1-[(4-{[3-(ethanesulfonyl)be...)
Affinity DataIC50:  1.80nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
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TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Forma Tm

US Patent
LigandPNGBDBM180260(US9676721, 4 1-({4-[(3-chloro-4-methylbenzene)sulf...)
Affinity DataIC50:  1.90nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Forma Tm

US Patent
LigandPNGBDBM180089(US9676721, 57 2-cyano-1-({4-[6-(morpholin-4-yl)pyr...)
Affinity DataIC50:  1.90nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Forma Tm

US Patent
LigandPNGBDBM180253(US9676721, 90 2-cyano-3-({4-[(4-fluorobenzene)sulf...)
Affinity DataIC50:  2nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Forma Tm

US Patent
LigandPNGBDBM181022(US9676721, 108 3-{[4-(benzenesulfonyl)phenyl]methy...)
Affinity DataIC50:  2nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Forma Tm

US Patent
LigandPNGBDBM181671(US9676721, 11 1-({4-[(4-chloro-3-fluorobenzene)sul...)
Affinity DataIC50:  2nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Forma Tm

US Patent
LigandPNGBDBM181024(US9676721, 80 2-cyano-1-{[4-(1-methyl-1H-indole-2-...)
Affinity DataIC50:  2.10nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Forma Tm

US Patent
LigandPNGBDBM180854(US9676721, 69 2-cyano-1-[(4-{[3-(propane-1-sulfona...)
Affinity DataIC50:  2.10nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Forma Tm

US Patent
LigandPNGBDBM180083(US9676721, 30 2-cyano-1-({4-[(3,4-dimethylbenzene)...)
Affinity DataIC50:  2.20nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Forma Tm

US Patent
LigandPNGBDBM180868(US9676721, 106 3-[(4-{[2-cyano-3-(pyridin-4-yl)car...)
Affinity DataIC50:  2.20nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Forma Tm

US Patent
LigandPNGBDBM180122(US9676721, 85 2-cyano-1-{[4-(4-methylpyridine-3-su...)
Affinity DataIC50:  2.30nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Forma Tm

US Patent
LigandPNGBDBM180255(US9676721, 38 2-cyano-1-({4-[(3-fluoro-5-methoxybe...)
Affinity DataIC50:  2.30nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Forma Tm

US Patent
LigandPNGBDBM181669(US9676721, 23 2-cyano-1-({4-[(2,4-dimethylbenzene)...)
Affinity DataIC50:  2.40nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Forma Tm

US Patent
LigandPNGBDBM181031(US9676721, 92 2-cyano-3-(pyridin-4-yl)-1-[(4-{[3-(...)
Affinity DataIC50:  2.5nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Forma Tm

US Patent
LigandPNGBDBM180922(US9676721, 53 2-cyano-1-({4-[(4-methylbenzene)sulf...)
Affinity DataIC50:  2.5nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Forma Tm

US Patent
LigandPNGBDBM180919(US9676721, 109 3-chloro-5-[(4-{[2-cyano-3-(pyridin...)
Affinity DataIC50:  2.60nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Forma Tm

US Patent
LigandPNGBDBM180065(US9676721, 1 (E)-3-({4-[(3-chlorobenzene)sulfonyl]...)
Affinity DataIC50:  2.60nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
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TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Forma Tm

US Patent
LigandPNGBDBM180091(US9676721, 3 1-({4-[(3-chloro-4-methoxybenzene)sul...)
Affinity DataIC50:  2.60nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Forma Tm

US Patent
LigandPNGBDBM180094(US9676721, 77 2-cyano-1-[(4-{[4-(propan-2-yloxy)be...)
Affinity DataIC50:  2.60nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Forma Tm

US Patent
LigandPNGBDBM180092(US9676721, 67 2-cyano-1-[(4-{[3-(propan-2-yl)benze...)
Affinity DataIC50:  2.90nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
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TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Forma Tm

US Patent
LigandPNGBDBM180102(US9676721, 99 2-cyano-3-(pyridin-4-yl)-1-{[4-(quin...)
Affinity DataIC50:  2.90nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Forma Tm

US Patent
LigandPNGBDBM181028(US9676721, 63 2-cyano-1-[(4-{[3-(3,5-dimethyl-1H-p...)
Affinity DataIC50:  3nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Forma Tm

US Patent
LigandPNGBDBM180259(US9676721, 10 1-({4-[(4-chloro-2-methoxybenzene)su...)
Affinity DataIC50:  3nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Forma Tm

US Patent
LigandPNGBDBM180917(US9676721, 100 2-cyano-3-[(4-{8-oxa-3-azabicyclo[3...)
Affinity DataIC50:  3nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Forma Tm

US Patent
LigandPNGBDBM180258(US9676721, 49 2-cyano-1-({4-[(4-fluoro-3-methylben...)
Affinity DataIC50:  3.10nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Forma Tm

US Patent
LigandPNGBDBM180126(US9676721, 68 2-cyano-1-[(4-{[3-(propan-2-yloxy)be...)
Affinity DataIC50:  3.20nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Forma Tm

US Patent
LigandPNGBDBM180927(US9676721, 40 2-cyano-1-({4-[(3-fluorobenzene)sulf...)
Affinity DataIC50:  3.20nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Forma Tm

US Patent
LigandPNGBDBM180256(US9676721, 33 2-cyano-1-({4-[(3,5-dimethylbenzene)...)
Affinity DataIC50:  3.30nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Forma Tm

US Patent
LigandPNGBDBM180254(US9676721, 8 1-({4-[(3-chloro-5-methylbenzene)sulf...)
Affinity DataIC50:  3.30nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Forma Tm

US Patent
LigandPNGBDBM180252(US9676721, 74 2-cyano-1-[(4-{[4-(1H-pyrazol-1-yl)b...)
Affinity DataIC50:  3.30nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Forma Tm

US Patent
LigandPNGBDBM181670(US9676721, 16 1-[(4-{[3-chloro-5-(trifluoromethyl)...)
Affinity DataIC50:  3.30nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Forma Tm

US Patent
LigandPNGBDBM180123(US9676721, 104 3-[(4-{[2-cyano-3-(pyridin-4-yl)car...)
Affinity DataIC50:  3.40nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Forma Tm

US Patent
LigandPNGBDBM180106(US9676721, 15 1-({4-[3-chloro-2-(morpholin-4-yl)py...)
Affinity DataIC50:  3.40nMpH: 7.5 T: 2°CAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 7.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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