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Compile Data Set for Download or QSAR
maximum 50k data
Found
185
Enz. Inhib. hit(s) with all data for entry = 1850
Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM344200
((2R)-1-[3-{[6-(4-acetylpiperazin-1-yl)-2-ethoxypyr...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.5nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM344204
((2R)-2-[3-{[6-(4-acetylpiperazin-1-yl)-2-ethoxypyr...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.5nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM344248
(N-{6-[(3S)-4-acetyl-3-(methoxymethyl)piperazin-1-y...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.80nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM344282
(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.10nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM344241
(N-{6-[(2S)-2-(hydroxymethyl)-4-(morpholin-4-ylcarb...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.30nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM344245
(N-{6-[(2R)-4-acetyl-2-(hydroxymethyl)piperazin-1-y...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.40nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM344277
(N-[6-(4-acetylpiperazin-1-yl)-2-methoxypyridin-3-y...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.90nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM344224
(N-{6-[4-(N′-cyano-N-methylcarbamimidoyl)pipe...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM344222
(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.10nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM344239
(N-{6-[(3S)-4-acetyl-3-(hydroxymethyl)piperazin-1-y...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.30nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM344205
(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.30nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM344290
(N-[6-(1-acetylpiperidin-4-yl)-2-ethoxypyridin-3-yl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.5nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM344279
(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.5nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM344217
(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.90nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM344240
(N-{6-[(2S)-4-acetyl-2-(hydroxymethyl)piperazin-1-y...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.90nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM344264
(N-[4-(4-acetylpiperazin-1-yl)-2-methoxyphenyl]-6,6...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.20nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM344201
(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.30nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM344196
(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.70nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM344281
(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.70nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM344195
(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.70nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM344203
(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.80nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM344289
(N-{6-(4-acetylpiperazin-1-yl)-2-[(1-oxidothietan-3...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.80nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM344285
(N-[6-(4-acetylpiperazin-1-yl)-2-(oxetan-3-yloxy)py...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.90nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM344115
(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.10nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM344280
(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.20nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM344284
(N-[6-(4-acetylpiperazin-1-yl)-2-(2,2,2-trifluoroet...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.20nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM344190
(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.30nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM344223
(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.30nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM344234
(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.40nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM344274
(5,5-dimethyl-N-(2-methyl-2H-indazol-5-yl)-4-oxo-4,...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.90nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM344210
(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM344244
(N-{6-[(3R)-4-acetyl-3-(hydroxymethyl)piperazin-1-y...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6.30nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM344263
(N-[2-methoxy-4-(piperazin-1-yl)phenyl]-6,6-dimethy...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6.40nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM344291
(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6.60nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM344202
((2S)-1-[3-{[6-(4-acetylpiperazin-1-yl)-2-ethoxypyr...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6.70nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM344225
(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6.80nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM344238
(N-{2-isopropoxy-6-[(3aR,6aR)-1-[(4-methylpiperazin...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6.90nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM344213
(N-[2-(2-hydroxy-2-methylpropoxy)-6-(morpholin-4-yl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6.90nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM344197
(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM344220
(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7.20nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM344251
(6-ethoxy-5-({[5-(2-methoxyethyl)-6,6-dimethyl-4-ox...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7.90nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM344221
((6R)¿N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8.5nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM344242
(N-{6-[(3S)-3-(dimethylamino)pyrrolidin-1-yl]-2-iso...)
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IC50: 10.2nM
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Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM344287
(N-{6-(4-acetylpiperazin-1-yl)-2-[(3S)-tetrahydrofu...)
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IC50: 10.2nM
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Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM344265
(N-(2-methyl-2H-indazol-5-yl)-4-oxo-4,7-dihydro-5H-...)
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IC50: 10.3nM
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Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM344246
(N-{6-[bis(2-hydroxyethyl)amino]-2-isopropoxypyridi...)
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IC50: 10.5nM
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Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM344235
(N-{6-[(3 aR,6aR)-hexahydropyrrolo[3,4-b]pyrrol-5(1...)
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IC50: 10.8nM
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US Patent
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Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM344286
(N-[6-(4-acetylpiperazin-1-yl)-2-(tetrahydro-2H-pyr...)
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IC50: 11nM
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Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM344229
(N-{2-methoxy-6-[4-(pyrrolidin-1-ylcarbonyl)piperaz...)
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IC50: 11.9nM
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Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Abbvie
US Patent
Ligand
BDBM344283
(N-[6-(4-acetylpiperazin-1-yl)-2-(2-methoxyethoxyl)...)
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IC50: 12.2nM
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