Compile Data Set for Download or QSAR
maximum 50k data
Found 125 Enz. Inhib. hit(s) with all data for entry = 2384
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM363780(3-Ethyl-6,7-dimethoxy-4-oxo-3,4-dihydro-phthalazin...)
Affinity DataIC50: <100nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM363781(2-(1-Ethyl-propyl)-6,7-dimethoxy-1-oxo-1,2-dihydro...)
Affinity DataIC50: <100nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM363782(2-Ethyl-7-methoxy-1-oxo-6-(2-quinolin-2-yl-ethoxy)...)
Affinity DataIC50: <100nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM363819(2-(1-Ethyl-propyl)-6,7-dimethoxy-1-oxo-1,2-dihydro...)
Affinity DataIC50: <100nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM363820(2-(1-Ethyl-propyl)-6,7-dimethoxy-1-oxo-1,2-dihydro...)
Affinity DataIC50: <100nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM363821(2-(1-Ethyl-propyl)-6,7-dimethoxy-1-oxo-1,2-dihydro...)
Affinity DataIC50: <100nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM363828(2-(1-Ethyl-propyl)-6,7-dimethoxy-1-oxo-1,2-dihydro...)
Affinity DataIC50: <100nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM363831(2-(1-Ethyl-propyl)-6,7-dimethoxy-1-oxo-1,2-dihydro...)
Affinity DataIC50: <100nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM363832(2-(1-Ethyl-propyl)-6,7-dimethoxy-1-oxo-1,2-dihydro...)
Affinity DataIC50: <100nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM363851(6,7-Dimethoxy-N-(5-methyl-2,3-dihydro-1H-inden-1-y...)
Affinity DataIC50: <100nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM363852(6,7-Dimethoxy-N-(4-methyl-2,3-dihydro-1H-inden-1-y...)
Affinity DataIC50: <100nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM363854(6,7-Dimethoxy-N-(6-methoxy-2,3-dihydro-1H-inden-1-...)
Affinity DataIC50: <100nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM363794(2-Ethyl-6,7-dimethoxy-N-(4-methylbenzyl)-1-oxo-1,2...)
Affinity DataIC50: <100nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM363888(N-Butyl-6,7-dimethoxy-1-oxo-2-[2-(2-quinolyl)ethyl...)
Affinity DataIC50: <100nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM363758(2-Ethyl-6,7-dimethoxy-1-oxo-1,2-dihydro-isoquinoli...)
Affinity DataIC50:  150nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM363765(2-Ethyl-6,7-dimethoxy-1-oxo-1,2-dihydro-isoquinoli...)
Affinity DataIC50:  150nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM363775(2-Ethyl-6,7-dimethoxy-1-oxo-1,2-dihydro-isoquinoli...)
Affinity DataIC50:  150nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM363776(2-Ethyl-6,7-dimethoxy-1-oxo-1,2-dihydro-isoquinoli...)
Affinity DataIC50:  150nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM363777(2-Ethyl-6,7-dimethoxy-1-oxo-1,2-dihydro-isoquinoli...)
Affinity DataIC50:  150nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM363778(2-Ethyl-6,7-dimethoxy-1-oxo-1,2-dihydro-isoquinoli...)
Affinity DataIC50:  150nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM363785(2-Ethyl-6,7-dimethoxy-N-(4-morpholinophenyl)-1-oxo...)
Affinity DataIC50:  150nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM363786(N-(3-Chlorobenzyl)-2-ethyl-6,7-dimethoxy-1-oxo-1,2...)
Affinity DataIC50:  150nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM363815(2-(1-Ethyl-propyl)-6,7-dimethoxy-1-oxo-1,2-dihydro...)
Affinity DataIC50:  150nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM363816(2-(1-Ethyl-propyl)-6,7-dimethoxy-1-oxo-1,2-dihydro...)
Affinity DataIC50:  150nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM363817(2-(1-Ethyl-propyl)-6,7-dimethoxy-1-oxo-1,2-dihydro...)
Affinity DataIC50:  150nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM363822(2-(1-Ethyl-propyl)-6,7-dimethoxy-1-oxo-1,2-dihydro...)
Affinity DataIC50:  150nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM363823(2-sec-Butyl-6,7-dimethoxy-1-oxo-1,2-dihydro-isoqui...)
Affinity DataIC50:  150nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM363833(2-(1-Ethyl-propyl)-6,7-dimethoxy-1-oxo-1,2-dihydro...)
Affinity DataIC50:  150nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM363844((S)-N-(1-(4-fluorophenyl)ethyl)-6,7-dimethoxy-1-ox...)
Affinity DataIC50:  150nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM363845(6,7-Dimethoxy-N-((4-methylthiazol-2-yl)methyl)-1-o...)
Affinity DataIC50:  150nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM363846(6,7-Dimethoxy-N-((2-methylthiazol-4-yl)methyl)-1-o...)
Affinity DataIC50:  150nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM363848(6,7-Dimethoxy-N-((5-methylfuran-2-yl)methyl)-1-oxo...)
Affinity DataIC50:  150nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM363850(N-(5-Fluoro-2,3-dihydro-1H-inden-1-yl)-6,7-dimetho...)
Affinity DataIC50:  150nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM363834(2-Ethyl-7-methoxy-1-oxo-1,2-dihydro-[2,6]naphthyri...)
Affinity DataIC50:  150nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM363835(3-(1-Ethyl-propyl)-6,7-dimethoxy-4-oxo-3,4-dihydro...)
Affinity DataIC50:  150nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM363836(6,7-Dimethoxy-1-oxo-2-(pentan-3-yl)-N-(pyridin-3-y...)
Affinity DataIC50:  150nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM363837(6,7-Dimethoxy-N-((5-methylthiophen-2-yl)methyl)-1-...)
Affinity DataIC50:  150nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM363839(N-((3,5-Dimethylisoxazol-4-yl)methyl)-6,7-dimethox...)
Affinity DataIC50:  150nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM363840(6,7-Dimethoxy-N-((5-methylthiazol-2-yl)methyl)-1-o...)
Affinity DataIC50:  150nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM363841(6,7-Dimethoxy-N-((3-methylisoxazol-5-yl)methyl)-1-...)
Affinity DataIC50:  150nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM363789(2-Ethyl-6,7-dimethoxy-N-(3-methoxyphenyl)-1-oxo-1,...)
Affinity DataIC50:  150nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM363794(2-Ethyl-6,7-dimethoxy-N-(4-methylbenzyl)-1-oxo-1,2...)
Affinity DataIC50:  150nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM363795(2-Ethyl-6,7-dimethoxy-N-(2-methylbenzyl)-1-oxo-1,2...)
Affinity DataIC50:  150nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM363797(2-Ethyl-6,7-dimethoxy-1-oxo-N-p-tolyl-1,2-dihydroi...)
Affinity DataIC50:  150nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM363801((S)-2-Ethyl-N-(1-(4-fluorophenyl)ethyl)-6,7-dimeth...)
Affinity DataIC50:  150nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM363806(N-(5,6-Dihydro-4H-cyclopenta[b]thiophen-4-yl)-2-et...)
Affinity DataIC50:  150nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM363812(7-Methoxy-1-oxo-2-(2-quinolin-2-yl-ethyl)-1,2-dihy...)
Affinity DataIC50:  150nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM363813(2-(1-Ethyl-propyl)-6,7-dimethoxy-1-oxo-1,2-dihydro...)
Affinity DataIC50:  150nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM363855(6,7-Dimethoxy-N-((4-methylthiophen-2-yl)methyl)-1-...)
Affinity DataIC50:  150nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland

US Patent
LigandPNGBDBM363856(6,7-Dimethoxy-N-((3-methylthiophen-2-yl)methyl)-1-...)
Affinity DataIC50:  150nMAssay Description:The PDE enzymatic reaction was carried out in assay buffer (20 mM Tris-HCl pH7.5, 10 mM MgCl2, 0.1% bovine serum albumin) containing enzyme and subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Displayed 1 to 50 (of 125 total ) | Next | Last >>
Jump to: