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Found 16 Enz. Inhib. hit(s) with all data for entry = 618
TargetHistone deacetylase 6(Homo sapiens (Human))
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM249365(US9464073, 002 | US9884850, Compound 2)
Affinity DataIC50:  2.40nMpH: 7.4 T: 2°CAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM249364(US9464073, 001 | US9884850, Compound 1)
Affinity DataIC50:  2.90nMpH: 7.4 T: 2°CAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM249366(US9464073, 003 | US9884850, Compound 3)
Affinity DataIC50:  3.70nMpH: 7.4 T: 2°CAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM249367(US9464073, 004 | US9884850, Compound 4)
Affinity DataIC50:  3.90nMpH: 7.4 T: 2°CAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM249365(US9464073, 002 | US9884850, Compound 2)
Affinity DataIC50:  108nMpH: 7.4 T: 2°CAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM249365(US9464073, 002 | US9884850, Compound 2)
Affinity DataIC50:  117nMpH: 7.4 T: 2°CAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM249365(US9464073, 002 | US9884850, Compound 2)
Affinity DataIC50:  671nMpH: 7.4 T: 2°CAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM249367(US9464073, 004 | US9884850, Compound 4)
Affinity DataIC50:  703nMpH: 7.4 T: 2°CAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM249367(US9464073, 004 | US9884850, Compound 4)
Affinity DataIC50:  833nMpH: 7.4 T: 2°CAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM249364(US9464073, 001 | US9884850, Compound 1)
Affinity DataIC50:  870nMpH: 7.4 T: 2°CAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM249366(US9464073, 003 | US9884850, Compound 3)
Affinity DataIC50:  961nMpH: 7.4 T: 2°CAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM249366(US9464073, 003 | US9884850, Compound 3)
Affinity DataIC50:  982nMpH: 7.4 T: 2°CAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM249364(US9464073, 001 | US9884850, Compound 1)
Affinity DataIC50:  1.04E+3nMpH: 7.4 T: 2°CAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM249367(US9464073, 004 | US9884850, Compound 4)
Affinity DataIC50:  1.82E+3nMpH: 7.4 T: 2°CAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM249366(US9464073, 003 | US9884850, Compound 3)
Affinity DataIC50:  4.38E+3nMpH: 7.4 T: 2°CAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
Acetylon Pharmaceuticals

US Patent
LigandPNGBDBM249364(US9464073, 001 | US9884850, Compound 1)
Affinity DataIC50:  6.20E+3nMpH: 7.4 T: 2°CAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent