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Found 18 Enz. Inhib. hit(s) with all data for entry = 624
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Kainos Medicine

US Patent
LigandPNGBDBM283120((R)-(6-(4-chlorophenyl)-1-methyl-8-(1-methyl-1H-py...)
Affinity DataIC50:  87nMAssay Description:Bromodomain binding assays were carried out in Reaction Biology (PA, USA) to test the degrees of the inventive compounds in inhibiting the human BRD4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Kainos Medicine

US Patent
LigandPNGBDBM283124((R)-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[...)
Affinity DataIC50:  100nMAssay Description:Bromodomain binding assays were carried out in Reaction Biology (PA, USA) to test the degrees of the inventive compounds in inhibiting the human BRD4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Kainos Medicine

US Patent
LigandPNGBDBM283122(US9884874, Compound 13)
Affinity DataIC50:  110nMAssay Description:Bromodomain binding assays were carried out in Reaction Biology (PA, USA) to test the degrees of the inventive compounds in inhibiting the human BRD4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Kainos Medicine

US Patent
LigandPNGBDBM283121(US9884874, Compound 12)
Affinity DataIC50:  110nMAssay Description:Bromodomain binding assays were carried out in Reaction Biology (PA, USA) to test the degrees of the inventive compounds in inhibiting the human BRD4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Kainos Medicine

US Patent
LigandPNGBDBM283127((R)-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[...)
Affinity DataIC50:  160nMAssay Description:Bromodomain binding assays were carried out in Reaction Biology (PA, USA) to test the degrees of the inventive compounds in inhibiting the human BRD4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Kainos Medicine

US Patent
LigandPNGBDBM283109((R)-(6-(4-chlorophenyl)-8-methoxy-1-methyl-4H-benz...)
Affinity DataIC50:  190nMAssay Description:Bromodomain binding assays were carried out in Reaction Biology (PA, USA) to test the degrees of the inventive compounds in inhibiting the human BRD4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Kainos Medicine

US Patent
LigandPNGBDBM283117((R)-(6-(4-chlorophenyl)-8-methoxy-1-methyl-4H-benz...)
Affinity DataIC50:  220nMAssay Description:Bromodomain binding assays were carried out in Reaction Biology (PA, USA) to test the degrees of the inventive compounds in inhibiting the human BRD4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Kainos Medicine

US Patent
LigandPNGBDBM283110((R)-(6-(4-chlorophenyl)-8-methoxy-1-methyl-4H-benz...)
Affinity DataIC50:  220nMAssay Description:Bromodomain binding assays were carried out in Reaction Biology (PA, USA) to test the degrees of the inventive compounds in inhibiting the human BRD4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Kainos Medicine

US Patent
LigandPNGBDBM283115((R)-(6-(4-cyanophenyl)-8-methoxy-1-methyl-4H-benzo...)
Affinity DataIC50:  230nMAssay Description:Bromodomain binding assays were carried out in Reaction Biology (PA, USA) to test the degrees of the inventive compounds in inhibiting the human BRD4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Kainos Medicine

US Patent
LigandPNGBDBM283125((R)-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[...)
Affinity DataIC50:  250nMAssay Description:Bromodomain binding assays were carried out in Reaction Biology (PA, USA) to test the degrees of the inventive compounds in inhibiting the human BRD4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Kainos Medicine

US Patent
LigandPNGBDBM283118((R)-(6-(4-chlorophenyl)-8-methoxy-1-methyl-4H-benz...)
Affinity DataIC50:  280nMAssay Description:Bromodomain binding assays were carried out in Reaction Biology (PA, USA) to test the degrees of the inventive compounds in inhibiting the human BRD4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Kainos Medicine

US Patent
LigandPNGBDBM283123((R)-(6-(4-chlorophenyl)-8-((2-hydroxyethyl)carbamo...)
Affinity DataIC50:  380nMAssay Description:Bromodomain binding assays were carried out in Reaction Biology (PA, USA) to test the degrees of the inventive compounds in inhibiting the human BRD4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Kainos Medicine

US Patent
LigandPNGBDBM283111((R)-(6-(4-chlorophenyl)-8-methoxy-1-methyl-4H-benz...)
Affinity DataIC50:  390nMAssay Description:Bromodomain binding assays were carried out in Reaction Biology (PA, USA) to test the degrees of the inventive compounds in inhibiting the human BRD4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Kainos Medicine

US Patent
LigandPNGBDBM283119((R)-(6-(4-chlorophenyl)-8-methoxy-1-methyl-4H-benz...)
Affinity DataIC50:  400nMAssay Description:Bromodomain binding assays were carried out in Reaction Biology (PA, USA) to test the degrees of the inventive compounds in inhibiting the human BRD4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Kainos Medicine

US Patent
LigandPNGBDBM283112((R)-(6-(4-chlorophenyl)-8-methoxy-1-methyl-4H-benz...)
Affinity DataIC50:  420nMAssay Description:Bromodomain binding assays were carried out in Reaction Biology (PA, USA) to test the degrees of the inventive compounds in inhibiting the human BRD4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Kainos Medicine

US Patent
LigandPNGBDBM283113((R)-(6-(4-chlorophenyl)-8-methoxy-1-methyl-4H-benz...)
Affinity DataIC50:  900nMAssay Description:Bromodomain binding assays were carried out in Reaction Biology (PA, USA) to test the degrees of the inventive compounds in inhibiting the human BRD4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Kainos Medicine

US Patent
LigandPNGBDBM283126((R)-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[...)
Affinity DataIC50:  900nMAssay Description:Bromodomain binding assays were carried out in Reaction Biology (PA, USA) to test the degrees of the inventive compounds in inhibiting the human BRD4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Kainos Medicine

US Patent
LigandPNGBDBM283114((R)-(6-(4-chlorophenyl)-1-methyl-4H-benzo[f][1,2,4...)
Affinity DataIC50:  1.41E+3nMAssay Description:Bromodomain binding assays were carried out in Reaction Biology (PA, USA) to test the degrees of the inventive compounds in inhibiting the human BRD4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent